Essential role of toll-like receptor 4 in Acinetobacter baumannii-induced immune responses in immune cells

2013 ◽  
Vol 54 ◽  
pp. 20-25 ◽  
Author(s):  
Chang-Hwan Kim ◽  
Yu-Jin Jeong ◽  
Junglim Lee ◽  
Soo-Jin Jeon ◽  
Se-Ra Park ◽  
...  
Keyword(s):  
Immune Responses ◽  
Acinetobacter Baumannii ◽  
Immune Cells ◽  
Essential Role ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4

scholarly journals Toll-Like Receptor 4 Is Required for Optimal Development of Th2 Immune Responses: Role of Dendritic Cells

2002 ◽  
Vol 168 (9) ◽  
pp. 4524-4530 ◽  
Author(s):  
Karim Dabbagh ◽  
Martin E. Dahl ◽  
Pamela Stepick-Biek ◽  
David B. Lewis
Keyword(s):  
Dendritic Cells ◽  
Immune Responses ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Optimal Development

Essential role of MD-2 in B-cell responses to lipopolysaccharide and Toll-like receptor 4 distribution

2002 ◽  
Vol 8 (6) ◽  
pp. 449-452 ◽  
Author(s):  
Kensuke Miyake ◽  
Yoshinori Nagai ◽  
Sachiko Akashi ◽  
Masakazu Nagafuku ◽  
Masato Ogata ◽  
...  
Keyword(s):  
B Cell ◽  
Essential Role ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Cell Responses ◽  
B Cell Responses

scholarly journals Mechanisms of TLR4-Mediated Autophagy and Nitroxidative Stress

2021 ◽  
Vol 11 ◽  
Author(s):  
Kunli Zhang ◽  
Qiuyan Huang ◽  
Shoulong Deng ◽  
Yecheng Yang ◽  
Jianhao Li ◽  
...  
Keyword(s):  
Public Health ◽  
Immune Cells ◽  
Reactive Nitrogen Species ◽  
Oxygen Species ◽  
Nitrogen Species ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Nitroxidative Stress ◽  
Recognition Receptor

Pathogenic infections have badly affected public health and the development of the breeding industry. Billions of dollars are spent every year fighting against these pathogens. The immune cells of a host produce reactive oxygen species and reactive nitrogen species which promote the clearance of these microbes. In addition, autophagy, which is considered an effective method to promote the destruction of pathogens, is involved in pathological processes. As research continues, the interplay between autophagy and nitroxidative stress has become apparent. Autophagy is always intertwined with nitroxidative stress. Autophagy regulates nitroxidative stress to maintain homeostasis within an appropriate range. Intracellular oxidation, in turn, is a strong inducer of autophagy. Toll-like receptor 4 (TLR4) is a pattern recognition receptor mainly involved in the regulation of inflammation during infectious diseases. Several studies have suggested that TLR4 is also a key regulator of autophagy and nitroxidative stress. In this review, we describe the role of TLR4 in autophagy and oxidation, and focus on its function in influencing autophagy-nitroxidative stress interactions.

Essential role of MD-2 in B-cell responses to lipopolysaccharide and Toll-like receptor 4 distribution

2002 ◽  
Vol 8 (6) ◽  
pp. 449-452 ◽  
Author(s):  
Kensuke Miyake ◽  
Yoshinori Nagai ◽  
Sachiko Akashi ◽  
Masakazu Nagafuku ◽  
Masato Ogata ◽  
...  
Keyword(s):  
B Cell ◽  
Essential Role ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Cell Responses ◽  
B Cell Responses

The essential role of toll like receptor-4 in the control ofAggregatibacter actinomycetemcomitansinfection in mice

2010 ◽  
Vol 37 (3) ◽  
pp. 248-254 ◽  
Author(s):  
Hayana Ramos Lima ◽  
Valéria Gelani ◽  
Ana Paula Fernandes ◽  
Thaís Helena Gasparoto ◽  
Sérgio Aparecido Torres ◽  
...  
Keyword(s):  
Essential Role ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4
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