Burkholderia pseudomallei-induced cell fusion in U937 macrophages can be inhibited by monoclonal antibodies against host cell surface molecules

2011 ◽  
Vol 13 (12-13) ◽  
pp. 1006-1011 ◽  
Author(s):  
Supaporn Suparak ◽  
Veerachat Muangsombut ◽  
Donporn Riyapa ◽  
Joanne M. Stevens ◽  
Mark P. Stevens ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Cell Surface ◽  
Host Cell ◽  
Cell Fusion ◽  
Burkholderia Pseudomallei ◽  
Cell Surface Molecules ◽  
Surface Molecules ◽  
Host Cell Surface

scholarly journals Generation of Monoclonal Antibodies Specific for Cell Surface Molecules Expressed on Early Mouse Endoderm

Stem Cells ◽  
2009 ◽  
Vol 27 (9) ◽  
pp. 2103-2113 ◽  
Author(s):  
Paul Gadue ◽  
Valerie Gouon-Evans ◽  
Xin Cheng ◽  
Ewa Wandzioch ◽  
Kenneth S Zaret ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Cell Surface ◽  
Cell Surface Molecules ◽  
Surface Molecules ◽  
Early Mouse

Characterization of Monoclonal Antibodies Against Cell Surface Molecules Associated with Cytotoxic Activity of Natural and Activated Killer Cells and Cloned CTL Lines

Hybridoma ◽  
1983 ◽  
Vol 2 (4) ◽  
pp. 423-437 ◽  
Author(s):  
HERGEN SPITS ◽  
GERRIT KEIZER ◽  
JANNIE BORST ◽  
COX TERHORST ◽  
ANNEMARIE HEKMAN ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Cell Surface ◽  
Cytotoxic Activity ◽  
Cell Surface Molecules ◽  
Killer Cells ◽  
Surface Molecules

scholarly journals Antibodies as antigens. The use of mouse monoclonal antibodies to focus human T cells against selected targets.

1988 ◽  
Vol 167 (2) ◽  
pp. 345-352 ◽  
Author(s):  
A Lanzavecchia ◽  
S Abrignani ◽  
D Scheidegger ◽  
R Obrist ◽  
B Dörken ◽  
...  
Keyword(s):  
T Cells ◽  
Monoclonal Antibodies ◽  
Cell Surface ◽  
Mhc Class Ii ◽  
Class Ii ◽  
Cell Surface Molecules ◽  
Tumor Patients ◽  
Surface Molecules ◽  
Human T Cells ◽  
Positive Target

We found that three tumor patients treated with mouse mAbs have T cells that recognize processed mouse Ig on autologous APC in a class II-restricted fashion, and we have shown that mouse mAbs directed against various cell surface molecules can be used as antigens to focus these T cells on an MHC class II-positive target of choice.

scholarly journals Infectious Keratitis: Secreted Bacterial Proteins That Mediate Corneal Damage

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Mary E. Marquart ◽  
Richard J. O'Callaghan
Keyword(s):  
Host Cell ◽  
Bacterial Infections ◽  
Cell Surface Molecules ◽  
Bacterial Proteins ◽  
Surface Molecules ◽  
Host Cell Death ◽  
Common Causes ◽  
Host Cell Surface ◽  
Stromal Collagen ◽  
Corneal Damage

Ocular bacterial infections are universally treated with antibiotics, which can eliminate the organism but cannot reverse the damage caused by bacterial products already present. The three very common causes of bacterial keratitis—Pseudomonas aeruginosa,Staphylococcus aureus, andStreptococcus pneumoniae—all produce proteins that directly or indirectly cause damage to the cornea that can result in reduced vision despite antibiotic treatment. Most, but not all, of these proteins are secreted toxins and enzymes that mediate host cell death, degradation of stromal collagen, cleavage of host cell surface molecules, or induction of a damaging inflammatory response. Studies of these bacterial pathogens have determined the proteins of interest that could be targets for future therapeutic options for decreasing corneal damage.

Analysis of Cell Surface Molecules on Human Platelets with Monoclonal Antibodies

1986 ◽  
Vol 75 (3) ◽  
pp. 141-146 ◽  
Author(s):  
Kiyotaka Hayashi ◽  
Koichi Furukawa ◽  
Shigeru Takamoto ◽  
Hiroshi Shiku ◽  
Kazumasa Yamada
Keyword(s):  
Monoclonal Antibodies ◽  
Cell Surface ◽  
Human Platelets ◽  
Cell Surface Molecules ◽  
Surface Molecules

scholarly journals Cholesterol and host cell surface proteins contribute to cell-cell fusion induced by the Burkholderia type VI secretion system 5

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0185715 ◽  
Author(s):  
Liam Whiteley ◽  
Maria Haug ◽  
Kristina Klein ◽  
Matthias Willmann ◽  
Erwin Bohn ◽  
...  
Keyword(s):  
Cell Surface ◽  
Host Cell ◽  
Cell Fusion ◽  
Secretion System ◽  
Surface Proteins ◽  
Type Vi Secretion System ◽  
Cell Surface Proteins ◽  
Type Vi Secretion ◽  
Host Cell Surface ◽  
Cell Cell
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