Idiopathic retroperitoneal fibrosis (Ormond's disease) as a transient risk factor for venous thromboembolism

2020 ◽  
Author(s):  
Rubén Alonso-Beato ◽  
Francisco Galeano-Valle ◽  
Pablo Demelo-Rodriguez
Keyword(s):  
Risk Factor ◽  
Venous Thromboembolism ◽  
Retroperitoneal Fibrosis ◽  
Idiopathic Retroperitoneal Fibrosis ◽  
Ormond’S Disease

Ormond's disease: Definizione e cenni anatomici del retroperitoneo: Ormond's disease: Definition and anatomic outlines of the retroperitoneum

1998 ◽  
Vol 65 (2) ◽  
pp. 253-256
Author(s):  
D. Schiavone ◽  
G. Carluccio
Keyword(s):  
Connective Tissue ◽  
Retroperitoneal Fibrosis ◽  
Idiopathic Retroperitoneal Fibrosis ◽  
Ormond’S Disease ◽  
Disease Definition

A presentation is given of the stages through which Ormond in 1962 managed to define Idiopathic Retroperitoneal Fibrosis (RPF), thereby giving it a precise clinical identity while the disease became known with his name. In the following years Ormond examined some etiopathogenetic hypotheses and showed that the etiology of RPF was still unknown, even if in some cases the cause had been traced to some medicines, such as methysergide, which were thought to act as haptens. The anatomical limits of the retroperitoneum and its structures are then outlined, in particular the retroperitoneal connective tissue.

Ormond's disease: Aspetti anatomo-patologici: Ormond's disease: Histopathological features

1998 ◽  
Vol 65 (2) ◽  
pp. 267-271
Author(s):  
M. Chilosi ◽  
G. Mariuzzi
Keyword(s):  
Differential Diagnosis ◽  
Retroperitoneal Fibrosis ◽  
Idiopathic Retroperitoneal Fibrosis ◽  
Clinical Role ◽  
Ormond’S Disease ◽  
Histopathological Features ◽  
Pathologic Features ◽  
Cell Components ◽  
Histopathological Studies

Histopathological studies have significantly contributed to clarifing the pathogenetic mechanisms of idiopathic retroperitoneal fibrosis (Ormond's disease), confirming in most cases its inflammatory nature. In this review we describe the principal pathologic features of the lesion, describing the different inflammatory and fibrogenic cell components. In addition, the differential diagnosis of Ormond's disease and the clinical role of histopathology and immunophenotypical analysis are briefly discussed.

scholarly journals Ormond’s disease accompanied by ankylosing spondylitis – a case report

2020 ◽  
Vol 66 (3) ◽  
Author(s):  
Paulina Żukowska ◽  
Jerzy Świerkot ◽  
Magdalena Szmyrka ◽  
Renata Sokolik ◽  
Piotr Wiland ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Ankylosing Spondylitis ◽  
Retroperitoneal Fibrosis ◽  
Clinical Symptoms ◽  
Fibrous Tissue ◽  
Late Presentation ◽  
Retroperitoneal Space ◽  
Idiopathic Retroperitoneal Fibrosis ◽  
Tissue Mass ◽  
Ormond’S Disease

Idiopathic retroperitoneal fibrosis, or Ormond’s disease, is a rare syndrome which is in essence the deposition of pathological fibrous tissue in the retroperitoneal space. In most cases, it is initially asymptomatic, but as the disease progresses, clinical symptoms develop. The main complaint are abdominal pain and symptoms resulting from the involvement of ureters, arterial and venous vessels. Diagnosis is based on computed tomography or magnetic resonance imaging, demonstrating a fibrotic tissue mass accumulated in the retroperitoneal space. Due to the typically late presentation of clinical symptoms, a diagnosis is difficult and is often made after complications occur. In our article, we present the case of a 71-year-old patient in whom coexisting ankylosing spondylitis and retroperitoneal fibrosis were diagnosed 15 years after non-specific abdominal pain occurred.

A case of idiopathic retroperitoneal fibrosis

2020 ◽  
Vol 8 (1) ◽  
pp. 101-107
Author(s):  
S.V. Shchekaturov ◽  
◽  
M.M. Kaabak ◽  
A.K. Zokoev ◽  
E.R. Charchyan ◽  
...  
Keyword(s):  
Retroperitoneal Fibrosis ◽  
Idiopathic Retroperitoneal Fibrosis

Anticoagulant dosing in renal impairment

Phlebologie ◽  
2015 ◽  
Vol 44 (06) ◽  
pp. 316-319 ◽  
Author(s):  
S. Harder
Keyword(s):  
Risk Factor ◽  
Venous Thromboembolism ◽  
Renal Impairment ◽  
Anticoagulant Therapy ◽  
Severe Renal Impairment ◽  
Dabigatran Etexilate ◽  
The Elderly ◽  
Thrombin Inhibitor ◽  
Safety And Efficacy ◽  
Direct Acting

SummaryAnticoagulants are widely used for prophylaxis and treatment of venous thromboembolism in the elderly, who commonly have renal impairment and other comorbidities. Renal impairment is a risk factor for bleeding and thrombosis during anticoagulant therapy and can influence the balance between the safety and efficacy of such agents. Some anticoagulants, such as fondaparinux and the direct acting oral thrombin inhibitor dabigatran etexilate are contraindicated for use in patients with severe renal impairment (eGFR <30 ml/min). However, also the direct acting oral FXa-inhibitors rivaroxaban, edoxaban and apixaban need caution regarding dosing advice or contraindications when used in patients with renal impairment.

scholarly journals Variable Symptomatology in Idiopathic Retroperitoneal Fibrosis

1983 ◽  
Vol 76 (12) ◽  
pp. 1023-1025 ◽  
Author(s):  
C D M Fletcher ◽  
P E M Jarrett
Keyword(s):  
Retroperitoneal Fibrosis ◽  
District Hospital ◽  
Differential Diagnoses ◽  
General Surgeon ◽  
Idiopathic Retroperitoneal Fibrosis

Idiopathic retroperitoneal fibrosis is uncommon enough to be placed low down on a list of differential diagnoses of any problem facing a general surgeon in a district hospital. In this paper, 4 cases of retroperitoneal fibrosis are described, all of whom presented within a 5-year period to the same surgeon; each described a different symptomatology. This paper serves to reiterate the diversity of presenting features in retroperitoneal fibrosis and to demonstrate that this condition may not be as rare as is widely believed.

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