Role of vitamin D in risk factors of patients with type 2 diabetes mellitus

2020 ◽  
Vol 154 (5) ◽  
pp. 151-156 ◽  
Author(s):  
Qingqing Zhang ◽  
Yucheng Wu ◽  
Yu Lu ◽  
Xiaoqiang Fei
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus

Role of vitamin D in risk factors of patients with type 2 diabetes mellitus

2020 ◽  
Vol 154 (5) ◽  
pp. 151-156
Author(s):  
Qingqing Zhang ◽  
Yucheng Wu ◽  
Yu Lu ◽  
Xiaoqiang Fei
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus

Assessment of the Role of Serum 25-Hydroxy Vitamin D Level on Coronary Heart Disease Risk With Stratification Among Patients With Type 2 Diabetes Mellitus

Angiology ◽  
2020 ◽  
Vol 72 (1) ◽  
pp. 86-92
Author(s):  
Abdülbari Bener ◽  
Abdulla O. A. A. Al-Hamaq ◽  
Susu M. Zughaier ◽  
Mustafa Öztürk ◽  
Abdülkadir Ömer
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Coronary Heart Disease ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
25 Hydroxy Vitamin D

We investigated the role of vitamin D on glycemic regulation and cardiac complications in patients with type 2 diabetes mellitus (T2DM). A total of 1139 patients (49.3% males vs 50.7% females) were included. Information on sociodemographic lifestyle, family history, blood pressure (BP), and coronary heart disease (CHD) complications was collected. Significant differences were found between males and females regarding age-groups ( P = .002), body mass index (BMI; P = .008), physical activity ( P = .010), sheesha smoking ( P = .016), cigarette smoking ( P = .002), hypertension ( P = .050), metabolic syndrome ( P = .026), and CHD ( P = .020). There were significant differences between vitamin D deficiency, insufficiency, and sufficiency in relation to age-group ( P = .002), income ( P = .002), waist circumference ( P = .002), hip circumference ( P = .028), waist–hip ratio ( P = .002), and BMI ( P = .002). Further, mean values of hemoglobin, magnesium, creatinine, hemoglobin A1c (HbA1c), total cholesterol, uric acid, and diastolic BP were significantly higher among patients with vitamin D deficiency compared with those with insufficiency and sufficiency. Multiple logistic regression analysis revealed that 25-hydroxy vitamin D, 25(OH)D, HbA1c, waist circumference, uric acid, duration of T2DM, total cholesterol, systolic and diastolic BP, and BMI were strong predictor risk factors for CHD among patients with T2DM. The present study supports that 25(OH)D may have a direct effect on CHD and on its risk factors.

scholarly journals Associations between Vitamin D and Type 2 Diabetes Mellitus: The Role of Vitamin D Receptor and Binding Protein

2020 ◽  
Vol 10 (04) ◽  
pp. 222-235
Author(s):  
Eman S. Arafat ◽  
Inass M. Taha ◽  
Shahad W. Kattan ◽  
Nouf Abubakr Babteen ◽  
Iman Fawzy
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Vitamin D Receptor ◽  
Binding Protein

scholarly journals Role of vitamin D in energy and bone metabolism in postmenopausal women with type 2 diabetes mellitus: A 6-month follow-up evaluation

2017 ◽  
Vol 9 (1) ◽  
pp. 211-222 ◽  
Author(s):  
Makiko Ogata ◽  
Naoko Iwasaki ◽  
Risa Ide ◽  
Miho Takizawa ◽  
Mizuho Tanaka ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Bone Metabolism ◽  
Postmenopausal Women

scholarly journals Role of vitamin D receptor (VDR) genetic polymorphism in onset of type 2 diabetes mellitus: A Review

2019 ◽  
Vol 4 (1) ◽  
pp. 1-9
Author(s):  
Naila Abdul Sattar ◽  
◽  
Fatma Hussain ◽  
Kathleen Gillespie ◽  
Siraj Udin Sajid ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Genetic Polymorphism ◽  
Vitamin D Receptor

The role of vitamin D deficiency and elevated inflammatory biomarkers as risk factors for the progression of diabetic nephropathy in patients with type 2 diabetes mellitus

2021 ◽  
Vol 19 (1) ◽  
pp. 1183-1192
Author(s):  
Ahmad El Askary ◽  
Amal F. Gharib ◽  
Mazen Almehmadi ◽  
Maha Mahfouz Bakhuraysah ◽  
Abdulaziz Ali Al Hajjiahmed ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Nephropathy ◽  
Vitamin D Deficiency ◽  
Diabetic Patients ◽  
Tnf Α

Abstract Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide. Albuminuria is the most sensitive marker for the early recognition of DN. Therefore, we aimed to study the risk factors of albuminuria as a marker of DN among diabetic patients. The study included 41 patients with type 2 diabetes mellitus (T2DM), 50 type 2 diabetic nephropathy (T2DN) patients with macroalbuminuria, 43 T2DN patients with microalbuminuria and 38 healthy controls. Logistic regression was used to detect the most significant risk factors for albuminuria. A high statistically significant difference was found between the groups regarding age, sex, body mass index (BMI), diabetes mellitus (DM) duration, glucose, glycated haemoglobin (HbA1c), creatinine, glomerular filtration rate (GFR), lipid profile, tumour necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), C-reactive protein (CRP), the albumin–creatinine ratio (ACR), vitamin D, total parathyroid hormone (PTH), urea, total calcium and chemerin (p < 0.001). It was found that the duration of DM, BMI, glucose, GFR, total cholesterol (TC), low-density lipoprotein (LDL), TNF-α, IL-6, CRP, ACR, vitamin D, PTH and chemerin are significant albuminuria risk factors in DN. Vitamin D deficiency and associated inflammatory mediators such as chemerin, TNF-α, IL-6 and CRP are the most essential risk factors for albuminuria in T2DM patients.

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