Inhibition of estrogen actions in human cancer ? current status and the future: A tribute to the late Professor Michael Reed

2011 ◽  
Vol 340 (2) ◽  
pp. 119
Author(s):  
Hironobu Sasano
Keyword(s):  
Human Cancer ◽  
Current Status ◽  
Late Professor ◽  
The Future

Nonmuscle-Invasive Bladder Cancer: What's Changing and What has Changed

2017 ◽  
Vol 84 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Ramanitharan Manikandan ◽  
Oscar Rodriguez ◽  
Rubén Parada ◽  
Joan Palou Redorta
Keyword(s):  
Bladder Cancer ◽  
Best Practice ◽  
Disease Recurrence ◽  
Invasive Bladder Cancer ◽  
Current Status ◽  
Optimal Care ◽  
Medline Search ◽  
Select Group ◽  
The Future ◽  
Nonmuscle Invasive Bladder Cancer

Purpose Nonmuscle-invasive bladder cancer (NMIBC) is a challenging disease to manage primarily due to its varied clinical course. The management of NMIBC has witnessed a widespread change with respect to its diagnosis and treatment. Although transurethral resection (TUR) and adjuvant bacillus Calmette–Guerin (BCG) stills remain the cornerstone, newer protocols has come into vogue to achieve optimal care. On the basis of a literature review, we aimed to establish ‘what changes has already occurred and what is expected in the future’ in NMIBC. Methods A Medline search was performed to identify the published literature with respect to diagnosis, treatment and future perspectives on NMIBC. Particular emphasis was directed to determinants such as the quality of TUR and the newer modifications, Re-TUR, current status of newer macroscopic and microscopic imaging, role of urinary biomarkers, clinical, histologic and molecular predictors of high-risk disease, administration of intravesical agents, salvage therapy in BCG recurrence and the current best practice guidelines were analyzed. Results and Conclusions Optimal TUR, restaging in select group, incorporation of newer endoscopic imaging and judicious administration of intravesical chemo-immunotherapeutic agents can contribute to better patient care. Although there is a plethora of urinary markers, there is insufficient evidence for their use in isolation. The future probably lies in identification of genetic markers to determine disease recurrence, nonresponders to standard treatment and early institution of alternative/targeted therapy.

Application of Probabilistic and Interactive Information in Verifying Machine System and Kernels Based on Relational Modality

2010 ◽  
Vol 143-144 ◽  
pp. 67-71 ◽  
Author(s):  
Dong Ping Li ◽  
Zhi Ming Qu
Keyword(s):  
World Wide Web ◽  
World Wide ◽  
Position Paper ◽  
Current Status ◽  
Moore’S Law ◽  
Moore's Law ◽  
Machine System ◽  
The World ◽  
The Future

The networking approach to the World Wide Web is defined not only by the exploration of architecture, but also by the confirmed need for interrupts. Given the current status of authenticated archetypes, steganographers dubiously desire the analysis of scatter/gather I/O. the focus in this position paper is not on whether Moore's Law can be made concurrent, distributed, and pervasive, but rather on proposing an analysis of 32 bit architectures (Grange). It is concluded that, using probabilistic and interactive information and based on relational modality, the machine system and kernels are verified, which is widely used in the future.

State-of-the-art literature review on inventory models for perishable products

2018 ◽  
Vol 15 (3) ◽  
pp. 306-346 ◽  
Author(s):  
Vaibhav Chaudhary ◽  
Rakhee Kulshrestha ◽  
Srikanta Routroy
Keyword(s):  
Inventory Management ◽  
Systemic Review ◽  
Current Status ◽  
Future Research ◽  
Inventory Models ◽  
Research Gaps ◽  
Content Type ◽  
Perishable Items ◽  
Perishable Inventory ◽  
The Future

PurposeThe purpose of this paper is to review and analyze the perishable inventory models along various dimensions such as its evolution, scope, demand, shelf life, replenishment policy, modeling techniques and research gaps.Design/methodology/approachIn total, 418 relevant and scholarly articles of various researchers and practitioners during 1990-2016 were reviewed. They were critically analyzed along author profile, nature of perishability, research contributions of different countries, publication along time, research methodologies adopted, etc. to draw fruitful conclusions. The future research for perishable inventory modeling was also discussed and suggested.FindingsThere are plethora of perishable inventory studies with divergent objectives and scope. Besides demand and perishable rate in perishable inventory models, other factors such as price discount, allow shortage or not, inflation, time value of money and so on were found to be combined to make it more realistic. The modeling of inventory systems with two or more perishable items is limited. The multi-echelon inventory with centralized decision and information sharing is acquiring lot of importance because of supply chain integration in the competitive market.Research limitations/implicationsOnly peer-reviewed journals and conference papers were analyzed, whereas the manuals, reports, white papers and blood-related articles were excluded. Clustering of literature revealed that future studies should focus on stochastic modeling.Practical implicationsStress had been laid to identify future research gaps that will help in developing realistic models. The present work will form a guideline to choose the appropriate methodology(s) and mathematical technique(s) in different situations with perishable inventory.Originality/valueThe current review analyzed 419 research papers available in the literature on perishable inventory modeling to summarize its current status and identify its potential future directions. Also the future research gaps were uncovered. This systemic review is strongly felt to fill the gap in the perishable inventory literature and help in formulating effective strategies to design of an effective and efficient inventory management system for perishable items.

scholarly journals Pediatric cardiovascular care in Uganda: Current status, challenges, and opportunities for the future

2017 ◽  
Vol 10 (1) ◽  
pp. 50 ◽  
Author(s):  
TwalibOlega Aliku ◽  
Sulaiman Lubega ◽  
Judith Namuyonga ◽  
Tom Mwambu ◽  
Michael Oketcho ◽  
...  
Keyword(s):  
Current Status ◽  
The Future ◽  
Challenges And Opportunities ◽  
Cardiovascular Care

scholarly journals Redesigning Scenarios and Defining Business Opportunities

2016 ◽  
Vol 6 (4) ◽  
pp. 01
Author(s):  
Hakan BÜTÜNER
Keyword(s):  
Environmental Analysis ◽  
Current Status ◽  
Competitive Advantages ◽  
Business Opportunities ◽  
The Future ◽  
The Status

<p>The purpose of this paper is to help businesses to define their business opportunities that are most attractive and feasible for them by using newly developed practical techniques. It is intended to find the factors that would affect and change the outlook mostly in the current status and anticipated future, based on the results obtained from environmental analysis. In short, using the trends to be revealed by the environmental analysis, it is possible to anticipate how the field of business in which we operate or plan to enter will evolve in the future. The status is reviewed according to the assumptions and the results to be obtained are evaluated. Thus, assumptions are grouped under various scenarios, their potential impacts on the industry are identified, and the potential status in the industry is defined. In conclusion, taking into consideration the characteristics of the business that offer competitive advantages, the potential opportunities for the business in the industry are identified. Another intention here is to provide strategic planners an easily understandable and applicable comprehensive procedure by assembling the disconnected and disorderly ideas, processes and techniques.</p>

scholarly journals Next Generation European Research Vessels: Current Status and Foreseeable Evolution

2019 ◽  
Author(s):  
Per Nieuwejaar ◽  
Valerie Mazauric ◽  
Christian Betzler ◽  
Mafalda Carapuco ◽  
Andre Cattrijsse ◽  
...  
Keyword(s):  
Position Paper ◽  
Research Vessel ◽  
Current Status ◽  
Marine Science ◽  
European Research ◽  
Human Capabilities ◽  
Policy Makers ◽  
The Future ◽  
Science Community ◽  
High Level

This position paper provides a review of the current European research vessel fleet, its capabilities and equipment, assessing its ability to support marine science across the globe now and into the future. It particularly looks at current and future capabilities in the context of deep sea and Polar research. It also takes a wider vision, assessing the importance of these vessels in the ocean and earth observing landscape. This review includes not only technological but also human capabilities, looking at training needs for crew and technicians to ensure they can continue to deliver on critical science needs. It also considers the ways in which the current European fleet is managed.This Position Paper sets out recommendations for how the fleet will need to develop in the future to ensure that it will continue to provide the same high level of support to science globally, as well as highlighting ways in which management could be made more efficient. It is aimed at national- and European-level policy makers and funders, as well as the marine science community and the research vessel operator community.

scholarly journals OVERVIEW OF RESEARCH OF MUSHROOMS IN SRI LANKA

2017 ◽  
Vol 40 (4) ◽  
pp. 399-403
Author(s):  
Samantha C. Karunarathna ◽  
Peter E. Mortimer ◽  
Jianchu Xu ◽  
Kevin D. Hyde
Keyword(s):  
Sri Lanka ◽  
Future Development ◽  
Native Species ◽  
Ornamental Plants ◽  
Current Status ◽  
Sri Lankan ◽  
Mycological Research ◽  
The Future ◽  
Available Information

According to recent estimates the mycota of Sri Lanka is highly diverse, yet it has been relatively little studied and remains poorly understood. Sri Lanka may contain up to 25,000 species of fungi, of which only a little more than 2000 are presently known, and this estimate does not take into account the large number of exotics introduced along with food, plantation, and ornamental plants. Mycological research in Sri Lanka has been limited to certain parts of the country, and the available information is widely dispersed, difficult to access, and plagued by synonymy. Commercially cultivable mushrooms were first introduced to Sri Lanka in 1985, and today both endemic and non-native species are cultivated. This paper addresses the current status of Sri Lankan mushroom research, and suggests measures which are needed to support the future development of Sri Lankan mycology.

scholarly journals Past, present and future of thermal gasification of biomass and waste

2020 ◽  
pp. 5-20
Author(s):  
Jitka Hrbek
Keyword(s):  
The Netherlands ◽  
Coal Gasification ◽  
Current Status ◽  
The Past ◽  
The Future ◽  
Future Potential ◽  
Waste Gasification

The thermal gasification has been used for nearly 200 years. At the beginning coal or peat were used as a feedstock to produce gas for cooking and lighting. Nowadays, the coal gasification is still actual, anyway, in times without fossils the biomass and waste gasification becomes more important. In this paper, the past, present and future of the biomass and waste gasification (BWG) is discussed. The current status of BWG in Austria, Denmark, Germany, Italy, the Netherlands, Sweden and USA is detailed described and the future potential of the technology is outlined.

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