Modifiable factors associated with symptomatic knee osteoarthritis: The Murakami cohort study

Maturitas ◽  
2019 ◽  
Vol 128 ◽  
pp. 53-59 ◽  
Author(s):  
Ryoya Takiguchi ◽  
Rintaro Komatsu ◽  
Kaori Kitamura ◽  
Yumi Watanabe ◽  
Akemi Takahashi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Knee Osteoarthritis ◽  
Factors Associated ◽  
Modifiable Factors ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee

scholarly journals Factors Associated with Functional Mobility in Women with Symptomatic Knee Osteoarthritis

2021 ◽  
Vol 24 (2) ◽  
pp. 121-126
Author(s):  
Gökşen GÖKŞENOĞLU ◽  
Nurdan PAKER ◽  
Derya BUĞDAYCI ◽  
Yelda SOLUK ÖZDEMİR ◽  
Sedef ERSOY ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Functional Mobility ◽  
Factors Associated ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee

scholarly journals Long-Term Effectiveness of Polymerized-Type I Collagen Intra-Articular Injections in Patients with Symptomatic Knee Osteoarthritis: Clinical and Radiographic Evaluation in a Cohort Study

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Adrián Borja-Flores ◽  
Salvador I. Macías-Hernández ◽  
Gabriela Hernández-Molina ◽  
Andric Perez-Ortiz ◽  
Eloy Reyes-Martínez ◽  
...  
Keyword(s):  
Cohort Study ◽  
Knee Osteoarthritis ◽  
Therapeutic Effect ◽  
Type I Collagen ◽  
Joint Space Width ◽  
Joint Space ◽  
Type I ◽  
Replacement Surgery ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee

Objective. Polymerized-type I collagen (polymerized-collagen) is a downregulator of inflammation and a tissue regenerator. The aim was to evaluate the effect of intra-articular injections (IAIs) of polymerized-collagen among patients with symptomatic knee osteoarthritis (OA) in delaying or preventing joint replacement surgery. Patients and Methods. This was a cohort study of 309 patients with knee OA. Patients with mild-to-moderate disease were treated weekly with IAIs of 2 mL of polymerized-collagen for six weeks (n = 309). Follow-up was for 6–60 months. The primary endpoints included the following determinations: (1) therapeutic effect; (2) survival from total knee replacement surgery (TKR); (3) Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and pain (visual analogue scale, VAS). Clinical improvement was defined as a decrease in pain exceeding 20 mm on the VAS and the achievement of at least 20% improvement from baseline with respect to the WOMAC score. Radiographic analysis was performed at baseline and 60 months. The joint space width in the medial, lateral, and patellofemoral compartments was calculated. Results. Patients who received IAIs of polymerized-collagen had a statistically significant improvement in the primary criteria (p<0.05). Kaplan–Meier survival analysis of the therapeutic effect demonstrated 98.8% survival at 60 months with TKR as the endpoint. There was no significant reduction in joint space in any compartment based on the analyzed radiographs. No serious adverse events were recorded. Conclusion. Polymerized-collagen increased the time to TKR by at least 60 months, modifying the disease course, improving functional disability, and decreasing pain.

scholarly journals Prevalence and factors associated with self-reported fatigue in individuals with symptomatic knee osteoarthritis: the most study

2018 ◽  
Vol 26 ◽  
pp. S217
Author(s):  
H.O. Fawole ◽  
J.L. Riskowski ◽  
A. Dell'Isola ◽  
M.P. Steultjens ◽  
S.F. Chastin ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Factors Associated ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee
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