Metabolic risk factors and recurrence of pelvic organ prolapse after primary repair in post-menopausal women

Maturitas ◽  
2019 ◽  
Vol 124 ◽  
pp. 140-141
Author(s):  
Giulia Gava ◽  
Renato Seracchioli ◽  
Maria Cristina Meriggiola
Keyword(s):  
Risk Factors ◽  
Pelvic Organ Prolapse ◽  
Primary Repair ◽  
Pelvic Organ ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Menopausal Women ◽  
Post Menopausal

scholarly journals A cohurt study on association and inflammatiory markers of cardio metabolic risk factors in pre and post menopausal women

2021 ◽  
Vol 9 (2) ◽  
pp. 112-115
Author(s):  
D. Jayarajan ◽  
V. Abirami
Keyword(s):  
Risk Factors ◽  
Plasma Lipids ◽  
Vascular Inflammation ◽  
Premenopausal Women ◽  
Fat Distribution ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Cvd Risk ◽  
Menopausal Women ◽  
Post Menopausal

Pre and post menopause were the complications faced by women globally that not only interferes in physical health but also in mental health of a woman. The menopause factors includes many traditional CVD risk factors, including changes in body fat distribution from agynoid to an android pattern, reduced glucose tolerance, abnormal plasma lipids, increased blood pressure, increased sympathetic tone, endothelial dysfunction and vascular inflammation . Menopause is a risk factor for (CVD) because estrogen withdrawal has a detrimental effect on cardiovascular function and metabolism .The present study aimed for inflammatory markers of cardio metabolic risk factors in post menopausal women and premenopausal women and the results recorded the significant level of elevation in all parameters compared with case and control samples and the significance was given as student’s t test(p<0.001).

scholarly journals Geriatric gynecology: need and spectrum

2020 ◽  
Vol 9 (6) ◽  
pp. 2556
Author(s):  
Mridula Singh ◽  
Sudha Chourasia
Keyword(s):  
Pelvic Organ Prolapse ◽  
Screening Program ◽  
Early Stage ◽  
Medical Science ◽  
Developed Countries ◽  
Pelvic Organ ◽  
Cross Sectional ◽  
Menopausal Women ◽  
Night Sweats ◽  
Post Menopausal

Background: Geriatric gynaecology deals with gynaecological pathologies essential in post-menopausal women aged 65 years and above. The spectrum of geriatric gynaecological disorders in India differs from those in developed countries as there are no effective screening program for early detection of cancer and the burden of ignorance and taboos. In this study we aim to find the spectrum of gynaecological disorders in geriatric women and establish the need of dedicated geriatric unit.Methods: A cross-sectional comparative study was conducted on menopausal women of age 45 years or above who attended gynecology OPD for general counselling about menopause or treatment of menopausal problems over the period of 6 months duration. All these menopausal women attending OPD during this interval were evaluated on the basis of pretested questionnaire.Results: Out of 234 post-menopausal women who entered the study, 29% women belong to geriatric group. Post-menopausal bleeding due to both malignant and benign causes and pelvic organ prolapse are the major problems in geriatric women whereas somatic complaints like flushing, night sweats are more common in younger menopausal women.Conclusions: Where the medical science has successfully increased the life expectancy, focused approach to geriatric gynecology around us is our responsibility, where female still hesitate to come out. The need for dedicated geriatric gynecology unit in India on urgent basis is emphasized by this study wherein cancers can be screened in early stage and severe lifestyle hampering conditions like pelvic organ prolapse can be treated timely.

scholarly journals Risk Profile of Uterovaginal Prolapse

2018 ◽  
Vol 1 (2) ◽  
pp. 42-46
Author(s):  
Una Pant ◽  
R. Pradhan ◽  
B. Aryal
Keyword(s):  
Risk Factors ◽  
Socioeconomic Status ◽  
Pelvic Organ Prolapse ◽  
Low Socioeconomic Status ◽  
Genital Prolapse ◽  
Pelvic Organ ◽  
Home Delivery ◽  
Uterovaginal Prolapse ◽  
The Mean ◽  
Post Menopausal

Introduction: Pelvic Organ Prolapse is a common problem in Nepal. The aim of this study was to assess the magnitude of pelvic organ prolapse and risk factors associated with it. Methods: This hospital based retrospective descriptive study was conducted in gynecological Out Patient Department of College of Medical Sciences Teaching Hospital, Bharatpur, Chitwan from October 2011 and September 2013.The data were retrieved from the records and analyzed. Women who were earlier subjected for surgical correction of prolapses Cases with pregnancy were excluded from study. Results: There were total 375 cases of genital prolapse out of total 2075 cases of total gynecological admission i.e. 18% incidence. The mean age of patients was 56.79 years with the mean parity of 5.67. 72% cases developed prolapse during their post-menopausal years. Majority of them (84%) lived in hilly area and (57.3%) cases were involved with heavy occupational activities. 50.7% of genital prolapse were from the lower socioeconomic status. Proplase was seen with patients with higher BMI (26-30). Risk factors identified were unsupervised home delivery, rapid succession of pregnancies, and no rest after delivery. Most common clinical presentation of Pelvis Organ Prolapse was mass per vagina (60%). Conclusions: Prolapse is common among rural, farmers, multiparous and post-menopausal women where most of them delivered at home with prolonged labor. Age, low socioeconomic status and heavy manual activities were associated with the prolapse.

Abstract MP44: Leukocyte Telomere Length and Risks of Incident Coronary Heart Disease and Mortality in a Racially Diverse Population

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Cara L Carty ◽  
Jingmin Liu ◽  
Charles Kooperberg ◽  
Megan Skinner Herndon ◽  
Andrea LaCroix ◽  
...  
Keyword(s):  
Risk Factors ◽  
Total Mortality ◽  
Metabolic Risk ◽  
Leukocyte Telomere Length ◽  
Diverse Population ◽  
Racially Diverse ◽  
Current Smoking ◽  
Menopausal Women ◽  
Race Ethnicity ◽  
Post Menopausal

Background: Telomeres are nucleotide repeat regions at the ends of chromosomes that maintain chromosomal structural integrity and genomic stability. Telomeres from circulating leukocytes can be readily measured; mean leukocyte telomere length (LTL) tends to decrease with age, vary by race/ ethnicity and is a putative marker of cellular aging. In studies of mainly white populations, shorter LTL has been associated with cardio-metabolic risk factors and increased risks of mortality and coronary heart disease (CHD), yet it is not clear whether these findings extend to other race/ethnicity groups. We sought to assess the relationship of LTL with risks of incident CHD and total mortality in a racially diverse population of post-menopausal women. Methods: Using a nested case-cohort design, African American (AA) and white women with incident CHD or mortality during a maximal follow-up of 19.4 years were randomly selected from the Women’s Health Initiative. LTL from baseline blood samples was assayed by Southern blotting. Race-stratified and risk factor-adjusted Cox proportional hazards models, weighted to account for the sampling scheme, were used to estimate the hazard of CHD or mortality. Results: A total of 1,525 women (858 whites and 667 AA) were included in the analyses. In whites, there were 367 incident CHD (292 mortality) events, while AA experienced 269 incident CHD (265 mortality) events. Cross-sectional LTL associations (p<0.05) with age, current smoking, and US recruitment region were observed in AA, whereas in whites, LTL was associated with age, current smoking and HDL cholesterol. Whites with longer LTL at baseline were less likely to have incident CHD, HR=0.58 (95%CI: 0.40-0.84), p=0.004, yet no significant association was observed in AA, HR=1.07 (95%CI: 0.71-1.61), p=0.74. This LTL-CHD association varied significantly by race/ethnicity, p=0.028. Similar trends were observed for total mortality, with longer LTL associated with reduced hazard in whites, HR=0.70 (95%CI: 0.46-1.06), but a slightly increased hazard in AA, HR=1.10 (95%CI: 0.80-1.53), though neither association was significant. In exploratory analyses of cause-specific mortality, increased LTL was associated with an increased, but non-significant hazard of cancer mortality in both AA and whites, p=0.17 and 0.28 respectively. Conclusion: We describe LTL associations with incident mortality, CHD and cardiovascular risk factors in post-menopausal women; these findings appear to vary by race/ethnicity. As a marker of chronic inflammation and cellular stress, LTL is robustly associated with CHD in whites, even after adjustment for cardio-metabolic risk factors including C-reactive protein, yet it does not appear to be associated with CHD in AA. Future studies exploring these race-specific differences may be warranted.

WITHDRAWN: Assessment of serum leptin and resistin levels in association with the metabolic risk factors of pre- and post-menopausal rural women in South India

2013 ◽  
Vol 7 (4) ◽  
pp. 233-237 ◽  
Author(s):  
Tanu Priya ◽  
Minakshi G. Chowdhury ◽  
Karunamoorthy Vasanth ◽  
Thangavel Mahalingam Vijayakumar ◽  
Kaliappan Ilango ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rural Women ◽  
South India ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Serum Leptin ◽  
Post Menopausal
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