Associations of ESR1 and ESR2 gene polymorphisms with metabolic syndrome and its components in postmenopausal women

Maturitas ◽  
2018 ◽  
Vol 115 ◽  
pp. 97-102 ◽  
Author(s):  
Karolina Kuźbicka ◽  
Dominik Rachoń ◽  
Anna Woziwodzka ◽  
Magda Rybicka ◽  
Krzysztof Piotr Bielawski
Keyword(s):  
Metabolic Syndrome ◽  
Postmenopausal Women ◽  
Gene Polymorphisms ◽  
Esr2 Gene

scholarly journals Association between ESR1 and ESR2 gene polymorphisms and hyperlipidemia in Chinese Han postmenopausal women

2009 ◽  
Vol 55 (1) ◽  
pp. 50-54 ◽  
Author(s):  
Teng Zhao ◽  
Di Zhang ◽  
Yun Liu ◽  
Daizhan Zhou ◽  
Zhuo Chen ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Gene Polymorphisms ◽  
Chinese Han ◽  
Esr2 Gene

scholarly journals Retraction Note: Associations between VDR Gene Polymorphisms and Osteoporosis Risk and Bone Mineral Density in Postmenopausal Women: A systematic review and Meta-Analysis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Liang Zhang ◽  
Xin Yin ◽  
Jingcheng Wang ◽  
Daolinag Xu ◽  
Yongxiang Wang ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Systematic Review ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Gene Polymorphisms ◽  
Meta Analysis ◽  
Mineral Density ◽  
Vdr Gene ◽  
Vdr Gene Polymorphisms ◽  
Osteoporosis Risk

Editor's Note: this Article has been retracted; the Retraction Note is available at https://doi.org/10.1038/s41598-021-88654-1.

scholarly journals No Interaction Effect between Interleukin-6 Polymorphisms and Acid Ash Diet with Bone Resorption Marker in Postmenopausal Women

2021 ◽  
Vol 18 (2) ◽  
pp. 827
Author(s):  
Sook Yee Lim ◽  
Yoke Mun Chan ◽  
Vasudevan Ramachandran ◽  
Zalilah Mohd Shariff ◽  
Yit Siew Chin ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Postmenopausal Women ◽  
Interaction Effect ◽  
Interleukin 6 ◽  
Gene Polymorphisms ◽  
Bone Resorption Marker ◽  
Dietary Intakes ◽  
Dietary Acid Load ◽  
Dietary Acid ◽  
Acid Load

Background: Evidence is growing that a high-acid diet might accelerate the rate of bone loss, and gene polymorphisms such as Interleukin 6 (IL6) -174G/C and -572G/C are related to bone deterioration. However, no study of the interaction between diet and IL6 polymorphisms has been conducted among Asians. Thus, the objective of this study was to determine whether IL6 gene polymorphisms modified the association between dietary acidity and the rate of bone resorption. Methods: This cross-sectional study recruited 203 postmenopausal women (age ranged from 51 to 85 years old) in community settings. The dietary intakes of the participants were assessed using a validated interviewer-administered semi-quantitative food frequency questionnaire (FFQ), while dietary acid load (DAL) was estimated using net endogenous acid production (NEAP). Agena® MassARRAY genotyping analysis and serum collagen type 1 cross-linked C-telopeptide (CTX1) were used to identify the IL6 genotype and as a bone resorption marker, respectively. The interactions between diet and single-nucleotide polymorphisms (SNPs) were assessed using linear regressions. Results: A total of 203 healthy postmenopausal women aged between 51 and 85 years participated in this study. The mean BMI of the participants was 24.3 kg/m2. In IL6 -174 G/C, all the participants carried the GG genotype, while the C allele was absent. Approximately 40% of the participants had a high dietary acid load. Dietary acid load (B = 0.15, p = 0.031) and the IL6 -572 CC genotype group (B = 0.14, p = 0.044) were positively associated with a higher bone resorption. However, there was no moderating effect of the IL6 genetic polymorphism on the relationship between and acid ash diet and bone resorption markers among the postmenopausal women (p = 0.79). Conclusion: High consumption of an acid ash diet and the IL6 -572 C allele seem to attribute to high bone resorption among postmenopausal women. However, our finding does not support the interaction effect of dietary acidity and IL6 (-174G/C and -572G/C) polymorphisms on the rate of bone resorption. Taken together, these results have given scientific research other candidate genes to focus on which may interact with DAL on bone resorption, to enhance planning for preventing or delaying the onset of osteoporosis among postmenopausal women.

scholarly journals Metabolic syndrome in premenopausal and postmenopausal women with type 2 diabetes: loss of protective effects of premenopausal status

2014 ◽  
Vol 13 (1) ◽  
Author(s):  
Manouchehr Nakhjavani ◽  
Mehrnaz Imani ◽  
Mehrdad Larry ◽  
Arash Aghajani-Nargesi ◽  
Afsaneh Morteza ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Postmenopausal Women ◽  
Protective Effects

The metabolic syndrome is associated with carotid atherosclerosis and arterial stiffness in asymptomatic, nondiabetic postmenopausal women

2017 ◽  
Vol 34 (1) ◽  
pp. 78-82 ◽  
Author(s):  
Irene Lambrinoudaki ◽  
Aikaterini Kazani ◽  
Eleni Armeni ◽  
Demetrios Rizos ◽  
Areti Augoulea ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Arterial Stiffness ◽  
Postmenopausal Women ◽  
Carotid Atherosclerosis ◽  
The Metabolic Syndrome
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