Distribution of clinical risk factors for fracture in a Brussels cohort of postmenopausal women: The FRISBEE study and comparison with other major cohort studies

Maturitas ◽  
2017 ◽  
Vol 106 ◽  
pp. 1-7 ◽  
Author(s):  
S.I. Cappelle ◽  
I. Ramon ◽  
C. Dekelver ◽  
S. Rozenberg ◽  
F. Baleanu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Studies ◽  
Postmenopausal Women ◽  
Clinical Risk Factors ◽  
Clinical Risk

scholarly journals Pelvic Organ Prolapse and Relationship with Skeletal Integrity

2009 ◽  
Vol 5 (3) ◽  
pp. 325-333 ◽  
Author(s):  
Lubna Pal
Keyword(s):  
Risk Factors ◽  
Pelvic Organ Prolapse ◽  
Fracture Risk ◽  
Postmenopausal Women ◽  
Pelvic Organ ◽  
Clinical Risk Factors ◽  
Mineral Density ◽  
Female Population ◽  
Clinical Risk ◽  
Age Related

Health burden related to osteoporotic fractures in an aging female population far exceeds that imposed by other chronic disorders such as cardiovascular disease and breast cancer. Bone mineral density assessment and clinical risk factors provide independent insights into fracture risk in individuals. A finite list of clinical risk factors are identified as prognostic of fracture risk, namely among aging women, including low body mass, compromised reproductive physiology (e.g., prolonged periods of amenorrhea and early menopause), parental and personal histories of fracture, and alcohol and tobacco use. Pelvic organ prolapse is a common gynecologic entity and a contributor to age-related morbidities. The purpose of this review is to communicate data identifying pelvic organ prolapse as another clinical risk factor for fracture risk in postmenopausal women and to increase the caregiver's vigilance in anticipating and instituting preventive care strategies to a population (i.e., postmenopausal women with clinically appreciable pelvic organ prolapse) that may be at an enhanced lifetime risk for skeletal fractures.

scholarly journals Fracture risk prediction using BMD and clinical risk factors in early postmenopausal women: Sensitivity of the WHO FRAX tool

2010 ◽  
Vol 25 (5) ◽  
pp. 1002-1009 ◽  
Author(s):  
Florence A Trémollieres ◽  
Jean-Michel Pouillès ◽  
Nicolas Drewniak ◽  
Jacques Laparra ◽  
Claude A Ribot ◽  
...  
Keyword(s):  
Risk Factors ◽  
Fracture Risk ◽  
Postmenopausal Women ◽  
Risk Prediction ◽  
Clinical Risk Factors ◽  
Clinical Risk ◽  
Early Postmenopausal Women ◽  
Fracture Risk Prediction

scholarly journals Clinical risk factors for Achilles tendinopathy: a systematic review

2019 ◽  
Vol 53 (21) ◽  
pp. 1352-1361 ◽  
Author(s):  
Arco C van der Vlist ◽  
Stephan J Breda ◽  
Edwin H G Oei ◽  
Jan A N Verhaar ◽  
Robert-Jan de Vos
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Cohort Studies ◽  
Achilles Tendinopathy ◽  
Activity Level ◽  
Clinical Risk Factors ◽  
Cochrane Library ◽  
Plantar Flexor ◽  
Clinical Risk ◽  
Flexor Strength

BackgroundAchilles tendinopathy is a common problem, but its exact aetiology remains unclear.ObjectiveTo evaluate the association between potential clinical risk factors and Achilles tendinopathy.DesignSystematic review.Data sourcesThe databases Embase, MEDLINE Ovid, Web of Science, Cochrane Library and Google Scholar were searched up to February 2018.Eligibility criteriaTo answer our research question, cohort studies investigating risk factors for Achilles tendinopathy in humans were included. We restricted our search to potential clinical risk factors (imaging studies were excluded).ResultsWe included 10 cohort studies, all with a high risk of bias, from 5111 publications identified. There is limited evidence for nine risk factors: (1) prior lower limb tendinopathy or fracture, (2) use of ofloxacin (quinolone) antibiotics, (3) an increased time between heart transplantation and initiation of quinolone treatment for infectious disease, (4) moderate alcohol use, (5) training during cold weather, (6) decreased isokinetic plantar flexor strength, (7) abnormal gait pattern with decreased forward progression of propulsion, (8) more lateral foot roll-over at the forefoot flat phase and (9) creatinine clearance of <60 mL/min in heart transplant patients. Twenty-six other putative risk factors were not associated with Achilles tendinopathy, including being overweight, static foot posture and physical activity level.ConclusionFrom an ocean of studies with high levels of bias, we extracted nine clinical risk factors that may increase a person’s risk of Achilles tendinopathy. Clinicians may consider ofloxacin use, alcohol consumption and a reduced plantar flexor strength as modifiable risk factors when treating patients with Achilles tendinopathy.Trial registration numberCRD42017053258.

Use of clinical risk factors to identify postmenopausal women with vertebral fractures

2006 ◽  
Vol 18 (1) ◽  
pp. 35-43 ◽  
Author(s):  
J. H. Tobias ◽  
A. P. Hutchinson ◽  
L. P. Hunt ◽  
E. V. McCloskey ◽  
M. D. Stone ◽  
...  
Keyword(s):  
Risk Factors ◽  
Postmenopausal Women ◽  
Vertebral Fractures ◽  
Clinical Risk Factors ◽  
Clinical Risk

scholarly journals Effects of soya isoflavones and exercise on body composition and clinical risk factors of cardiovascular diseases in overweight postmenopausal women: a 6-month double-blind controlled trial

2010 ◽  
Vol 105 (8) ◽  
pp. 1199-1209 ◽  
Author(s):  
Stéphane Choquette ◽  
Éléonor Riesco ◽  
Éric Cormier ◽  
Tommy Dion ◽  
Mylène Aubertin-Leheudre ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Composition ◽  
Postmenopausal Women ◽  
Synergistic Effects ◽  
Controlled Trial ◽  
Assessment Model ◽  
Clinical Risk Factors ◽  
Mineral Density ◽  
Double Blind ◽  
Clinical Risk

Results from a pilot project indicate that isoflavones and exercise could have an additive effect on body composition and clinical risk factors of CVD in postmenopausal women. The objective of the present study was to assess the combined effect of exercise and isoflavones in overweight-to-obese postmenopausal women. In this double-blind randomised controlled trial, 100 overweight-to-obese (BMI 29·9 (sd 3·2) kg/m2) postmenopausal women were assigned to four groups: (1) placebo (PLA); (2) isoflavones (ISO); (3) exercise and placebo (Ex+PLA); (4) exercise and isoflavones (Ex+ISO). The supplementation contained 70 mg/d of isoflavones. Exercise consisted of three weekly sessions of resistance training and aerobics. Outcome measures included fat mass (FM), lean body mass (LBM), bone mineral density, lipid profile, fasting glucose, fasting insulin and insulin resistance (homeostasis assessment model). The main effects of exercise were observed for total FM (P = 0·02), FM% (P < 0·01), trunk FM% (P = 0·05), arm FM% (P < 0·01), leg FM% (P = 0·02), arm LBM (P < 0·01), leg LBM (P = 0·02) and C-reactive protein (P < 0·01). A main effect was detected for isoflavones in improving leg FM% (P = 0·05). No interactions were observed between isoflavones and exercise. In conclusion, it was observed that 6 months of exercise brought favourable changes in total FM, FM% and LBM in overweight postmenopausal women. No synergistic effects were observed between exercise and isoflavones. However, isoflavones could have a beneficial effect on leg FM%.

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