Serum ferritin level is positively associated with insulin resistance and metabolic syndrome in postmenopausal women: A nationwide population-based study

Maturitas ◽  
2017 ◽  
Vol 103 ◽  
pp. 3-7 ◽  
Author(s):  
Mi-Ra Cho ◽  
Jin-Kyung Park ◽  
Won-Jun Choi ◽  
A-Ra Cho ◽  
Yong-Jae Lee
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Postmenopausal Women ◽  
Serum Ferritin ◽  
Serum Ferritin Level ◽  
Ferritin Level ◽  
Population Based ◽  
Population Based Study

scholarly journals Metabolic syndrome and serum ferritin level in postmenopausal women in urban cities in Enugu State, Nigeria

2016 ◽  
Vol 2 (9) ◽  
pp. 215 ◽  
Author(s):  
Ekene E. Chukwukelu ◽  
Lawrence U.S. Ezeanyika ◽  
Jane E. Onyia-Pat ◽  
Edwin N. Okafor
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
High Density Lipoprotein ◽  
Postmenopausal Women ◽  
High Blood Pressure ◽  
Serum Ferritin ◽  
High Density Lipoprotein Cholesterol ◽  
Serum Ferritin Level ◽  
Ferritin Level ◽  
Density Lipoprotein

<p class="abstract"><strong>Background:</strong> Physiological and biochemical changes that alter the general health of women are seen in menopause which include increase in adiposity and elevated serum ferritin. There is a dearth of information on the prevalence and common risk factors of MS and their association with iron stores of the body among postmenopausal women (POMW) in Enugu. Hence, this study was carried out to determine the prevalence of metabolic syndrome, the most prevalent components of metabolic syndrome and its relationship with serum ferritin level in postmenopausal women in Enugu, Nigeria.</p><p class="abstract"><strong>Methods:</strong> The study was a cross sectional study, carried out from February to August 2013 among two hundred and twenty four (224) apparently healthy postmenopausal women aged 40 to 83 years. Metabolic syndrome was defined using National Cholesterol Education Programme, Adult Treatment Panel III criteria.  </p><p class="abstract"><strong>Results:</strong> The most frequent components of metabolic syndrome (MS) seen among the subjects were high waist circumference (WC) (70.1%), high blood pressure (66.5%) and low high density lipoprotein cholesterol (25.4%). The prevalence of metabolic syndrome among the women was 29.0% while the mean level of serum ferritin of subjects with metabolic syndrome showed no significant (p &gt;0.05) difference when compared to subjects without MS.</p><strong>Conclusions:</strong> The most frequent cluster of the risk factor of MS in the population studied was high WC, high blood pressure and low high density lipoprotein cholesterol (HDL). Although serum ferritin is slightly associated with FPG and WHR, it may not be used as diagnostic tool for MS in the group studied.

Clinical significance of serum ferritin level as an independent predictor of insulin resistance in Korean men

2015 ◽  
Vol 107 (1) ◽  
pp. 187-193 ◽  
Author(s):  
Sung Keun Park ◽  
Won Joon Choi ◽  
Chang-Mo Oh ◽  
Min-Gi Kim ◽  
Woo Taek Ham ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Clinical Significance ◽  
Serum Ferritin ◽  
Serum Ferritin Level ◽  
Independent Predictor ◽  
Ferritin Level

Association Between Serum Ferritin Levels and Low Bone Mineral Density in Postmenopausal Osteoporosis Women

2020 ◽  
Author(s):  
Lama ALjeshi ◽  
Shaden Haddad
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Postmenopausal Osteoporosis ◽  
Bone Mineral ◽  
Serum Ferritin ◽  
Serum Ferritin Level ◽  
Ferritin Level ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Femur Neck

As women go through menopause, serum estrogen decreases, and ferritin increases. Ferritin is an essential component of the body, but many studies have stated that ferritin, which exceeds the normal physiological range, may potentially cause health problems in women. The aim of this study is to investigate the relationship between bone mineral density and serum ferritin levels in post-menopausal women and to evaluate serum ferritin levels as a potential biomarker for postmenopausal osteoporosis. Serum ferritin levels were measured in 62 postmenopausal women with low bone mineral density, and in 18 postmenopausal healthy control women using a standardized Enzyme-Linked Immune Sorbent Assay (ELISA) kit. Bone mineral density BMD was assessed at the lumbar spine and femoral neck. The mean serum ferritin level was significantly higher in the postmenopausal women with low BMD group (group 1) than in the normal control group (group 2), respectively (mean=262.69 vs. 181.44 ng/ml, (P<0.05), and serum ferritin level was negatively correlated with BMD among low BMD postmenopausal women's group (R= -0.628, P=0.0001), and in the healthy postmenopausal group (R= -0.052, P=0.838). A comparison of the BMD between spine and femur neck sites shows that the frequency of low BMD in the spine site is higher than the femur neck site. Our findings show that increased serum ferritin levels were associated with low bone mineral density in postmenopausal osteoporosis.

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