scholarly journals Increased fracture risk in patients with type 2 diabetes mellitus: An overview of the underlying mechanisms and the usefulness of imaging modalities and fracture risk assessment tools

Maturitas ◽  
2014 ◽  
Vol 79 (3) ◽  
pp. 265-274 ◽  
Author(s):  
Ellis A.C. de Waard ◽  
Tineke A.C.M. van Geel ◽  
Hans H.C.M. Savelberg ◽  
Annemarie Koster ◽  
Piet P.M.M. Geusens ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Risk Assessment ◽  
Type 2 Diabetes Mellitus ◽  
Fracture Risk ◽  
Assessment Tools ◽  
Imaging Modalities ◽  
Risk Assessment Tools ◽  
Underlying Mechanisms

Risk assessment of adult residents in ile-ife, South-Western Nigeria for type 2 diabetes mellitus

2013 ◽  
pp. 1-1
Author(s):  
Gbadebo Ajani ◽  
Rosemary Ikem ◽  
Adenike Enikuomehin ◽  
David Soyoye ◽  
Babatope Kolawole
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Risk Assessment ◽  
Type 2 Diabetes Mellitus

Trabecular Bone Score in Thais with or without Type 2 Diabetes

2020 ◽  
Vol 103 (11) ◽  
pp. 1131-1137
Keyword(s):  
Diabetes Mellitus ◽  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fracture Risk ◽  
Trabecular Bone ◽  
Trabecular Bone Score ◽  
Mineral Density ◽  
Men And Women

Background: When compared to people without type 2 diabetes mellitus (T2DM), people with T2DM have an increase in fracture risk despite having higher bone mineral density (BMD). Many studies in Caucasians demonstrated that trabecular bone score (TBS) is lower in people with T2DM than those without. The utility of TBS as a fracture risk assessment tool in Asians with T2DM is currently unclear. Objective: To compared lumbar spine (LS) BMD and TBS in Thais with or without T2DM and investigate the correlation between TBS and hemoglobin A1c (HbA1c) and diabetes duration in participants with T2DM. Materials and Methods: The present study was a cross-sectional study that included 97 participants with T2DM (37 men and 60 women) and 342 participants without T2DM (174 men and 168 women). LS-BMD and TBS were obtained. Results: Men and women with T2DM were older and had higher body mass index (BMI). Men with T2DM had significant higher LS-BMD (1.051±0.166 versus 0.972±0.125, p=0.009) and non-significant lower TBS (1.333±0.084 versus 1.365±0.096, p=0.055) than those without. Similarly, women with T2DM had significant higher LS-BMD (0.995±0.155 versus 0.949±0.124, p=0.021) and lower TBS (1.292±0.105 versus 1.382±0.096, p<0.001). After adjusting for age and BMI, T2DM predicted higher BMD in men (p<0.001), but not in women (p=0.143). T2DM was not associated with TBS after adjusting for age and BMI in both genders (p=0.403 and p=0.151 in men and women, respectively). TBS did not correlate with HbA1c in both genders. However, TBS was non-significantly associated with diabetes duration in women (p=0.073), but not in men (p=0.639). Conclusion: T2DM significantly predicted higher LS-BMD only in men and was not independently associated with TBS in both genders. These data highlighted that, in T2DM, there was some variation in the clinical usefulness of BMD and TBS in predicting osteoporotic fractures with regard to clinical characteristic of participants. Keywords: Bone mineral density, Type 2 diabetes mellitus, Trabecular bone score

Comparison of IDRS and ADA Diabetes Risk Assessment Tools Reveals Different Rsk Score in Same Population: A Cross-Sectional Analysis in a Tertiary Care Hospital

2021 ◽  
Vol 5 (1) ◽  
pp. 10-18
Author(s):  
N. Akter ◽  
N.K. Qureshi
Keyword(s):  
Type 2 Diabetes ◽  
Risk Assessment ◽  
High Risk ◽  
Risk Score ◽  
Diabetes Risk ◽  
Assessment Tools ◽  
Cross Sectional ◽  
Risk Assessment Tools ◽  
Predicted Risk

Background: To identify individuals at high risk of developing type2 diabetes (T2DM), use of a validated risk-assessment tool is currently recommended. Nevertheless, recent studies have shown that risk scores that are developed in the same country can lead to different results of an individual. The Objective of study was to reveal whether two different risk-assessment tools predict similar or dissimilar high-risk score in same population. Method: This cross-sectional analytical study was carried upon 336 non-diabetic adults visiting the outpatient department (OPD) of Medicine, MARKS Medical College & Hospital, Bangladesh from October 2018 to March 2019. Woman having previous history of Gestational Diabetes Mellitus (GDM) were also included. Both the Indian Diabetes risk Score (IDRS) and the American Diabetes (ADA) Risk Score questionnaire were used to collect the data on demographic and clinical characteristics, different risk factors of an individual subject, and to calculate predicted risk score for developing T2DM. Results: Among 336 subjects, 53.6% were female. The mean (±SD) age of the study subjects was 38.25±1.12 years. The average IDRS predicted risk score of developing T2DM was more in female subjects than male [p<0.05]. Whereas the ADA predicted increased risk score of developing type 2 diabetes was more in male subjects than female (p<0.05). IDRS categorized 37.2 % of individuals at high risk for developing diabetes; [p=0.10], while the ADA risk tool categorized 20.2% subjects in high risk group; [p<0.001]. Conclusions: The results indicate that risk for developing type 2 diabetes varies considerably according to the scoring system used. To adequately prevent T2DM, risk scoring systems must be validated for each population considered.

A Descriptive Study to Assess the Risk of Stroke among Patients with Hypertension and Type 2 Diabetes Mellitus at a Selected Hospital, Bangalore

2021 ◽  
Vol 6 (3) ◽  
pp. 407-412
Author(s):  
Leena Dorothy W ◽  
Pavithra C ◽  
Umadevi A K
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Risk Assessment ◽  
Type 2 Diabetes Mellitus ◽  
Stroke Risk ◽  
Family Type ◽  
Survey Method ◽  
Risk Category

Objective: Stroke is a major public health problem, both in developed and developing countries. Stroke is becoming an important cause of early death and disability in India due to increasing prevalence of the major key modifiable risk factors like type 2 diabetes mellitus and hypertension. Hence there is an urgent need for recognition of stroke risk factors and its warning signs. With this intention the present study aimed to assess the risk of stroke among patients with hypertension and type 2 diabetes mellitus. Methods: A non-experimental, descriptive survey method was adopted. Samples were selected by using quota sampling technique and 60 hypertensive and type 2 diabetes mellitus patients who met the inclusion criteria were selected for the study. Data were collected by an interview technique using a modified stroke risk assessment tool by the National Stroke Association, USA. Results: Out of 60 samples 48.3% of them were in high-risk category, 28.3% were in caution and 23.3% in low-risk category. There was a significant association found in relation to socio demographic variables such as education qualification, type of family, type of diet, weight and complications of hypertension (P<0.05). Discussion: The findings of the study suggested that there is an increased risk of stroke in hypertension and type 2 diabetes patients which can be aggravated by other risk factors and co-morbid conditions. Hence modifying these risk factors by changing lifestyle can help in prevention of stroke. Keywords: Stroke, risk assessment, hypertension and type 2 diabetes mellitus, comorbid conditions.

Dietary fibers in the prevention of type 2 diabetes mellitus

2021 ◽  
pp. 97-114
Author(s):  
Ellen E. Blaak ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Dietary Fiber ◽  
Positive Impact ◽  
Metabolic Health ◽  
Dietary Fibers ◽  
Fermentative Capacity ◽  
Underlying Mechanisms

This chapter reviews how dietary fibers can be used to prevent Type 2 diabetes mellitus. Dietary fibers are a heterogenous group of food compounds. The physicochemical properties of dietary fibers determine their effects on gastrointestinal and metabolic health, including effect on gastro-intestinal transit, glycemic response, microbial composition and fermentative capacity. Most fiber rich foods contain insoluble, prebiotic and viscous fibers in varying ratios. The chapter begins by discussing underlying mechanisms of action of insoluble fibers. It then goes on to discuss the various dietary fiber intervention studies, specifically focusing on prebiotic fibers and soluble viscous fibers. The chapter concludes by highlighting the importance of consuming high levels dietary fiber and whole grains and their positive impact on metabolic health.

scholarly journals AB0819 HANDGRIP STRENGTH PREDICTS HIGH FRACTURE RISK IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

2019 ◽  
Author(s):  
Federica Bellone ◽  
Nunziata Morabito ◽  
Agostino Gaudio ◽  
Gabriella Martino ◽  
Alberto Sardella ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fracture Risk ◽  
Handgrip Strength ◽  
High Fracture
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