Efficacy and tolerability of the Black cohosh (Actaea racemosa) ethanolic extract BNO 1055 on climacteric complaints: A double-blind, placebo- and conjugated estrogens-controlled study

Maturitas ◽  
2006 ◽  
Vol 55 ◽  
pp. S83-S91 ◽  
Author(s):  
Wolfgang Wuttke ◽  
Karel Rauš ◽  
Christoph Gorkow
Keyword(s):  
Ethanolic Extract ◽  
Black Cohosh ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Conjugated Estrogens ◽  
Actaea Racemosa ◽  
Climacteric Complaints

Effect of Bellergal Retard on climacteric complaints: a double-blind, placebo-controlled study

Maturitas ◽  
1987 ◽  
Vol 9 (3) ◽  
pp. 227-234 ◽  
Author(s):  
M.G.M. Bergmans ◽  
J.M.W.M. Merkus ◽  
R.S. Corbey ◽  
L.A. Schellekens ◽  
J.M.H. Ubachs
Keyword(s):  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Climacteric Complaints

scholarly journals Actaea racemosa L. Is More Effective in Combination with Rhodiola rosea L. for Relief of Menopausal Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study

2020 ◽  
Vol 13 (5) ◽  
pp. 102
Author(s):  
Lali Pkhaladze ◽  
Nina Davidova ◽  
Archil Khomasuridze ◽  
Ramaz Shengelia ◽  
Alexander G. Panossian
Keyword(s):  
Psychological Symptoms ◽  
Symptom Relief ◽  
Repeated Administration ◽  
Menopausal Symptoms ◽  
Black Cohosh ◽  
Rhodiola Rosea ◽  
Controlled Study ◽  
Double Blind ◽  
Actaea Racemosa ◽  
Significant Difference

Background: The aim of this study was to assess the efficacy and safety of a new herbal preparation (Menopause Relief EP®), the hybrid combination of Actaea racemosa L. (black cohosh, BC) and Rhodiola rosea L. (RR) root extracts, compared with the most effective dose of BC extract in women with menopausal complaints. Methods: A total of 220 women were randomly assigned to receive two capsules either BC (6.5 mg), BC500 (500 mg), Menopause Relief EP® (206,5), or placebo once per day for 12 weeks. The efficacy endpoints were relief of menopausal symptoms, measured using the Kupperman Menopausal Index (KMI), Menopause Relief Score (MRS), and menopause Utian Quality of Life (UQOL) index. Results: The menopause symptom relief effects of RR-BC were significantly superior in all tests to the effects of BC and placebo after their repeated administration for 6 and 12 weeks. There was no statistically significant difference between the effects of BC and BC500 over time. RR-BC significantly improved the QOL index in patients, compared to BC, BC500, and placebo, mainly due to the beneficial effects on the emotional and health domains. Conclusions: BC is more effective in combination with RR in relief of menopausal symptoms, particularly psychological symptoms.

A randomized, double-blind, placebo-controlled study on the effect of conjugated estrogens on skin thickness

1994 ◽  
Vol 170 (2) ◽  
pp. 642-649 ◽  
Author(s):  
Rodolphe Maheux ◽  
Françoise Naud ◽  
Michel Rioux ◽  
Raynald Grenier ◽  
André Lemay ◽  
...  
Keyword(s):  
Controlled Study ◽  
Skin Thickness ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Conjugated Estrogens

884: Phase I, Double-Blind, Placebo-Controlled Study in Healthy Male Subjects to Investigate the Safety, Tolerability, and Pharmacokinetics of DA-8159

2004 ◽  
Vol 171 (4S) ◽  
pp. 234-234 ◽  
Author(s):  
Harin Padma-Nathan ◽  
Jae Seung Pacik ◽  
Byoung Ok Ahn ◽  
Kyung Koo Kang ◽  
Mi Young Bahng ◽  
...  
Keyword(s):  
Phase I ◽  
Controlled Study ◽  
Healthy Male ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Male Subjects
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