Multilayer modification on titanium surface for in situ delivery of MicroRNAs

2014 ◽  
Vol 133 ◽  
pp. 243-246 ◽  
Author(s):  
Xinming Zhang ◽  
Shengli Zhu ◽  
Zhaoyang Li ◽  
Xubo Yuan ◽  
Zhenduo Cui ◽  
...  
Keyword(s):  
2017 ◽  
Vol 9 (22) ◽  
pp. 18609-18618 ◽  
Author(s):  
Mimi Wan ◽  
Jin Zhang ◽  
Qi Wang ◽  
Shuyue Zhan ◽  
Xudong Chen ◽  
...  

2020 ◽  
Vol 845 ◽  
pp. 156301 ◽  
Author(s):  
Cong Wu ◽  
Yufei Tang ◽  
Kang Zhao ◽  
Bobo Mao ◽  
Xingbo Ru

Materials ◽  
2020 ◽  
Vol 13 (3) ◽  
pp. 697
Author(s):  
Vaclav Babuska ◽  
Jana Kolaja Dobra ◽  
Ludek Dluhos ◽  
Jana Dvorakova ◽  
Jana Moztarzadeh ◽  
...  

Titanium offers excellent biocompatibility and extraordinary mechanical properties. As a result, it is used as a material for dental implants. Implants infected by peri-implantitis can be cleaned for successful re-osseointegration. Optimal surface properties, such as roughness and wettability, have a significant impact on cell adhesion. The aim of this study was to evaluate the adhesion and proliferation of osteoblasts on the surface of repeatedly cleaned nanostructured titanium samples. Human osteoblast-like cells MG-63 were seeded on nanostructured titanium specimens manufactured from rods produced by the equal channel angular pressing. For surface characterization, roughness and wettability were measured. Cell adhesion after 2 h as well as cell proliferation after 48 h from plating was assessed. We have found that this repeated cleaning of titanium surface reduced cell adhesion as well as proliferation. These events depend on interplay of surface properties, such as wettability, roughness and topography. It is difficult to distinguish which factors are responsible for these events and further investigations will be required. However, even after the several rounds of repeated cleaning, there was a certain rate of adhesion and proliferation recorded. Therefore the attempts to save failing implants by using in situ cleaning are promising.


2015 ◽  
Vol 349 ◽  
pp. 93-100 ◽  
Author(s):  
Y.R. Xu ◽  
H.D. Liu ◽  
Y.M. Chen ◽  
M.I. Yousaf ◽  
C. Luo ◽  
...  

2014 ◽  
Vol 936 ◽  
pp. 663-668 ◽  
Author(s):  
Guo Xin Tan ◽  
Ying Tan ◽  
Cheng Yun Ning ◽  
Lin Zhang ◽  
Lei Zhou ◽  
...  

Gelatin methacrylate (GelMA) hydrogel comprised of modified natural extracellular matrix (ECM) components, making it a potentially attractive material for surface modification. In this paper, we hypothesize that establishing a GelMA hydrogel coating on titanium surface will accelerate osseointegration. Titanium substrates were silanized with 3-Aminopropyltriethoxysilane (APTES), which was treated by alkali-heated treatment firstly. The GelMA hydrogel coating was constructed on the silanized titanium surface by in situ photopolymerization under UV illumination. Adsorption of bovine serum albumin (BSA) onto modifed titanium surfaces was investigated. The results showed that GelMA-coated titanium adsorbed greater amount of protein than other Ti surfaces. The differences in protein adsorption behavior could result in very different initial cellular behavior on GelMA-coated titanium implant surfaces.


2020 ◽  
Vol 505 ◽  
pp. 144604 ◽  
Author(s):  
Abdalla Abdal-hay ◽  
Karan Gulati ◽  
Tulio Fernandez-Medina ◽  
Ma Qian ◽  
Saso Ivanovski

Langmuir ◽  
2002 ◽  
Vol 18 (21) ◽  
pp. 8033-8039 ◽  
Author(s):  
Koreyoshi Imamura ◽  
Takaharu Sakiyama ◽  
Kazuhiro Nakanishi

Sign in / Sign up

Export Citation Format

Share Document