Biomimetic synthesis of silver nanoparticles by aqueous extract of Syzygium aromaticum

2012 ◽  
Vol 75 ◽  
pp. 33-35 ◽  
Author(s):  
K. Vijayaraghavan ◽  
S.P. Kamala Nalini ◽  
N. Udaya Prakash ◽  
D. Madhankumar
2019 ◽  
Vol 33 (5) ◽  
pp. e4867 ◽  
Author(s):  
B. Ajitha ◽  
Y. Ashok Kumar Reddy ◽  
Yonghee Lee ◽  
Min Jun Kim ◽  
Chi Won Ahn

2020 ◽  
Vol 11 (1) ◽  
pp. 8110-8120

The present findings were focused on green synthesis of silver nanoparticles through an aqueous extract of Saraca indica. The stability of the nanoparticle was achieved through the optimization of physico-chemical parameters. The sharp UV-visible absorption maximum at 400 was observed for biological synthesized silver nanoparticles. The spectroscopic analysis was thus used to assess the formation of silver nanoparticles. The AFM analysis did analyze the morphology of the nanocomposite, which was further confirmed through TEM micrograph. The electron micrograph image discloses that silver nanoparticles were polydispersed and dominantly as spherical with size ranges from 40nm to 100nm. The average size distribution was 49nm. The chemical reductions of Ag+ ions were further confirmed through FTIR. The biogenic silver nanoparticle and their drug formulation showed profound antibacterial activity against pathogenic bacteria. The flavonoids rich binding of silver nanoparticle showed great medicinal potential and can be used for the treatment of several harmful infectious diseases. Hence, plant-based metal nanoparticles meet the demand for less toxic formulation during drug development and its delivery.


2009 ◽  
Vol 12 (1) ◽  
pp. 237-246 ◽  
Author(s):  
A. Tripathy ◽  
Ashok M. Raichur ◽  
N. Chandrasekaran ◽  
T. C. Prathna ◽  
Amitava Mukherjee

Author(s):  
Reslee Elsa Varghese ◽  
Ragavan D ◽  
Saranya Sivaraj ◽  
Dasararaju Gayathri ◽  
Gomathi Kannayiram

  Objective: In the present study, antioxidant and anti-inflammatory activity of Syzygium aromaticum (clove) silver nanoparticles (clove AgNP’s) was evaluated.Methods: Gas chromatography-mass spectrometry technique was used to identify the compounds present in the aqueous extract of clove. Fourier transform infrared (FT-IR) analysis was done to characterize the clove silver AgNP’s. 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay was performed to evaluate the antioxidant property of nanoparticles (0.05 and 0.25 mg/ml) and aqueous extracts (0.05, 0.1, and 0.25 mg/ml) of clove. The anti-inflammatory property of the clove AgNP’s was determined by inhibition of protein denaturation and downregulation of interleukin-1 beta. In silico molecular docking studies was performed using Schrodinger Maestro software.Results: Eugenol was found to be highest with 16.27%. The AgNP’s exhibited dose-dependent antioxidant property. AgNP’s scavenged 80% of radical at the concentration of 0.25 mg/ml. The scavenging activity of AgNP’s markedly increased when compared to aqueous extract at the same concentration. Inhibition of protein denaturation assay also revealed AgNP’s showing the highest activity (66%) when compared with drug aspirin (55%) and aqueous extract (56%). In the enzyme-linked immunosorbent assay (ELISA) method, AgNP’s showed better inhibition (80%) when compared to aqueous extract (60%). Among 15 compounds, two compounds (eugenol and methyl 14-methylpentadecanoate) showed good glide energy, docking score, and hydrogen-bonded active site interactions with the protein interleukin-1 beta.Conclusion: As AgNP’s were more active than the aqueous extract, it may be considered for pharmacological activity against inflammatory disorders.


RSC Advances ◽  
2021 ◽  
Vol 11 (24) ◽  
pp. 14624-14631
Author(s):  
Pablo Eduardo Cardoso-Avila ◽  
Rita Patakfalvi ◽  
Carlos Rodríguez-Pedroza ◽  
Xochitl Aparicio-Fernández ◽  
Sofía Loza-Cornejo ◽  
...  

Gold and silver nanoparticles were synthesized at room temperature using an aqueous extract from dried rosehips acting as reducing and capping agents with no other chemicals involved.


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