Bonelike apatite formation on carbon microspheres

2007 ◽  
Vol 61 (11-12) ◽  
pp. 2502-2505 ◽  
Author(s):  
Chengtie Wu ◽  
Jiang Chang
Langmuir ◽  
2010 ◽  
Vol 26 (6) ◽  
pp. 4069-4073 ◽  
Author(s):  
Lifang Niu ◽  
Huiyi Kua ◽  
Daniel H. C. Chua

2003 ◽  
Vol 254-256 ◽  
pp. 459-462 ◽  
Author(s):  
Kawashita Masakazu ◽  
Xin-Yu Cui ◽  
Hyun Min Kim ◽  
Tadashi Kokubo ◽  
Takashi Nakamura

2005 ◽  
Vol 284-286 ◽  
pp. 239-242 ◽  
Author(s):  
Dora A. Cortés-Hernández ◽  
A. Medina Ramírez ◽  
José C. Escobedo-Bocardo ◽  
M.A. López ◽  
J.M. Almanza-Robles

Wollastonite ceramics was used in a biomimetic method to promote apatite formation on a Co-Cr-Mo alloy (ASTM F-75). The metallic samples were initially chemically treated in a 5M NaOH aqueous solution. The treated samples were immersed for 7 days in SBF on a bed of wollastonite and then immersed 7 or 14 days in 1.5SBF. For comparative purposes no wollastonite was used during the first 7 days in some tests. A homogeneous bonelike apatite layer was formed on the samples immersed in SBF on the wollastonite bed. The morphology and the Ca/P ratio of the layer were closely similar to those observed on the existing bioactive systems. A thinner homogeneous bonelike apatite layer was formed on the samples immersed in SBF and 1.5SBF without using wollastonite. However, the morphology and the Ca/P ratio of this layer differs slightly to that observed on the existing bioactive systems. The immersion of the samples during the first days in SBF on a wollastonite bed improves significantly the quality and thickness of the bonelike apatite layer.


2003 ◽  
Vol 254-256 ◽  
pp. 139-142 ◽  
Author(s):  
Tadashi Kokubo ◽  
Teruyuki Himeno ◽  
Hyun Min Kim ◽  
Kawashita Masakazu ◽  
Takashi Nakamura

1999 ◽  
Vol 599 ◽  
Author(s):  
T. Kokubo ◽  
H.-M. Kim ◽  
H. Takadama ◽  
M. Uchida ◽  
S. Nishiguchi ◽  
...  

AbstractThe present authors previously showed that titanium metal, which was exposed to 5.OMNaOH solution at 60°C for 24 h and heat-treated at 600°C for 1 h, spontaneously forms a bonelike apatite layer on its surface in the living body, and tightly bonds to the bone through the apatite layer. In the present study, mechanism of the apatite formation on the bioactive titanium metal was investigated in an acellular simulated body fluid (SBF). A thin sodium titanate layer was formed on the surface of the titanium metal by the NaOH and heat treatments. The sodium titanate layer released Na+ ions via exchange with H3O+ ions in SBF, to form a lot of Ti-OH groups on its surface. The Ti-OH groups first combined with Ca2+ ions in SBF, and then later with PO43- ions to form the apatite. Titania and Na2O-TiO2 gels prepared by a sol-gel method as model substances of the sodium titanate layer on the surface of the titanium metal showed that Ti-OH groups of anatase structure are effective for the apatite nucleation, whereas those of amorphous structure and Na2Ti5O11 crystal are not effective.


2008 ◽  
Vol 91 (12) ◽  
pp. 3943-3949 ◽  
Author(s):  
Takeshi Iwasaki ◽  
Yumi Tanaka ◽  
Miho Nakamura ◽  
Akiko Nagai ◽  
Kazuaki Hashimoto ◽  
...  

2004 ◽  
Vol 84 (9) ◽  
pp. 2041-2044 ◽  
Author(s):  
Masaki Uchida ◽  
Hyun-Min Kim ◽  
Tadashi Kokubo ◽  
Fumiaki Miyaji ◽  
Takashi Nakamura

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