Identification of adult knee primary bone tumour symptom presentation: A qualitative study

2016 ◽  
Vol 26 ◽  
pp. 54-61 ◽  
Author(s):  
Lucinda C.C. Gosling ◽  
Alison B. Rushton
Keyword(s):  
Qualitative Study ◽  
Bone Tumour ◽  
Symptom Presentation ◽  
Primary Bone Tumour ◽  
Primary Bone

scholarly journals Growth in the Lower Limb Following Chemotherapy for a Malignant Primary Bone Tumour: A Straight-Line Graph

Sarcoma ◽  
1997 ◽  
Vol 1 (2) ◽  
pp. 75-77 ◽  
Author(s):  
Paul Cool ◽  
Mark Davies ◽  
Rob J. Grimer ◽  
Simon R. Carter ◽  
Roger M. Tillman
Keyword(s):  
Lower Limb ◽  
Line Graph ◽  
Bone Tumour ◽  
Straight Line ◽  
Primary Bone Tumour ◽  
Primary Bone

Primary Bone Tumour Indication and Planning of En Bloc Resection

Spine Surgery ◽  
2019 ◽  
pp. 513-522
Author(s):  
Dominique A. Rothenfluh ◽  
Etienne Bourassa-Moreau
Keyword(s):  
Bone Tumour ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc ◽  
Primary Bone Tumour ◽  
Primary Bone

Regenerative therapy with mesenchymal stem cells at the site of malignant primary bone tumour resection: what are the risks of early or late local recurrence?

2014 ◽  
Vol 38 (9) ◽  
pp. 1825-1835 ◽  
Author(s):  
Philippe Hernigou ◽  
Charles Henri Flouzat Lachaniette ◽  
Jerome Delambre ◽  
Nathalie Chevallier ◽  
Helene Rouard
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Local Recurrence ◽  
Bone Tumour ◽  
Tumour Resection ◽  
Regenerative Therapy ◽  
Primary Bone Tumour ◽  
Primary Bone

Paediatric bone lesions: diagnostic accuracy of imaging correlation and CT-guided needle biopsy for differentiating benign from malignant lesions

2021 ◽  
pp. 20201234
Author(s):  
Alessandro Vidoni ◽  
Ian Pressney ◽  
Asif Saifuddin
Keyword(s):  
Diagnostic Accuracy ◽  
Needle Biopsy ◽  
Bone Tumour ◽  
Final Diagnosis ◽  
Imaging Diagnosis ◽  
Ct Guided ◽  
Primary Bone Tumour ◽  
Primary Bone ◽  
Malignant Lesions ◽  
Sensitivity Specificity

Objective: To determine the sensitivity, specificity and accuracy of CT-guided needle biopsy (CT-NB) for distinguishing benign and malignant lesions in children with suspected primary bone tumours, and to assess the correlation between imaging diagnosis and final diagnosis. Methods: Retrospective review of children who underwent CT-NB of a suspected primary bone tumour between October 2016 and October 2019. Data collected included anatomical location, imaging diagnosis, type of needle, type of biopsy sample, CT-NB diagnosis, final diagnosis and post-procedural complications. The final diagnosis was established based on surgical histology or clinical/imaging follow-up. Results: 125 patients met the inclusion criteria (68M, 57F: mean age 11 years; range 10 months–18 years). Biopsy was performed using a 10 cm Jamshidi needle (10G n = 96; 13 G n = 8); 14G Tru-Cut needle (n = 18); 14G Temno needle (n = 3). The commonest anatomical locations were the femur (n = 40), tibia (n = 25) and humerus (n = 16), while the commonest diagnoses were osteosarcoma (n = 35), CRMO (n = 15) and LCH (n = 14). A benign tumour was correctly identified on imaging in 100% of cases, and a malignant tumour in 95.8%. Sensitivity, specificity and diagnostic accuracy of CT-NB for distinguishing malignant from benign lesions were 98%, 100 and 99%. Of 24 indeterminate biopsy results, all that had a non-aggressive radiological appearance were benign. No immediate complications were recorded. Conclusion: CT-NB represents a safe and very effective tool for differentiating benign and malignant lesions in children presenting with a suspected primary bone tumour. Suspected radiological diagnosis plays a pivotal role in the management of indeterminate biopsy results. Advances in knowledge: Paediatric bone tumours pose a significant diagnostic and therapeutic challenge. The interpretation of the imaging findings is essential for the successful management of indeterminate histological results.

scholarly journals UK Guidelines for the Management of Bone Sarcomas

Sarcoma ◽  
2010 ◽  
Vol 2010 ◽  
pp. 1-14 ◽  
Author(s):  
Robert Grimer ◽  
Nick Athanasou ◽  
Craig Gerrand ◽  
Ian Judson ◽  
Ian Lewis ◽  
...  
Keyword(s):  
Bone Tumour ◽  
Palpable Mass ◽  
Children And Young People ◽  
Reference Centre ◽  
Primary Bone Tumour ◽  
Nice Guidance ◽  
Specialist Centre ◽  
Bone Sarcomas ◽  
Primary Bone ◽  
The Uk

These guidelines have been developed in order to provide an overview and a set of broad-based key recommendations for the management of patients with bone sarcomas in the UK. They have taken into consideration the most up-to-date scientific literature along with the recent recommendations by the European Society of Medical Oncology. The principles of the NICE guidance on both “improving outcomes for patients with sarcomas” and “improving outcomes with children and young people with cancer” have been incorporated. As care evolves, it is acknowledged that these guidelines will need updating. The key recommendations are that bone pain or a palpable mass should always lead to further investigation and patients with clinicoradiological findings suggestive of a primary bone tumour should be sent to a reference centre. Patients should then have their care managed at such a specialist centre by a fully accredited multidisciplinary team.

Chondrosarcoma in the humerus of a goat

2010 ◽  
Vol 23 (04) ◽  
pp. 273-276 ◽  
Author(s):  
M. Hilbe ◽  
S. Ohlert ◽  
K. Nuss ◽  
T. Schmid
Keyword(s):  
Bone Tumour ◽  
Lytic Lesion ◽  
Bone Lesions ◽  
Pathological Findings ◽  
Saanen Goat ◽  
Cortical Destruction ◽  
Primary Bone Tumour ◽  
Shoulder Region ◽  
Grade Ii ◽  
Primary Bone

SummaryThe clinical, radiographical and histo-pathological findings of a chondrosarcoma in the humerus of a goat are discussed. An 11-year-old female Saanen goat was admitted for evaluation of chronic, progressive left forelimb lameness. Clinical examination revealed signs of pain in the shoulder region. Radiographs of the scapulohumeral joint showed a large lytic lesion of the proximal third of the humerus with cortical destruction, intralesional calcification and marked periosteal reactions. Differential diagnoses included aggressive bone lesions as seen with osteomyelitis or a primary bone tumour, such as osteosarcoma, chondrosarcoma or fibrosarcoma. The goat was euthanatized for humane reasons because of the poor prognosis. On the basis of the histopathological findings, the lesion was diagnosed as grade II chondrosarcoma. The tumour had already spread to the lungs and the left prescapular lymph node at the time of diagnosis.

Sign in / Sign up

Export Citation Format

Share Document