Distinct metabolic effects of resveratrol on lipogenesis markers in mice adipose tissue treated with high-polyunsaturated fat and high-protein diets

Life Sciences ◽  
2016 ◽  
Vol 153 ◽  
pp. 66-73 ◽  
Author(s):  
Keila Lopes Mendes ◽  
Lucinéia de Pinho ◽  
João Marcus Oliveira Andrade ◽  
Alanna Fernandes Paraíso ◽  
Jamille Fernandes Lula ◽  
...  
Reproduction ◽  
2011 ◽  
Vol 141 (5) ◽  
pp. 697-706 ◽  
Author(s):  
Gina C Micke ◽  
Tracy M Sullivan ◽  
I Caroline McMillen ◽  
Sheridan Gentili ◽  
Vivienne E A Perry

Changes in maternal nutrient intake during gestation alterIGFreceptor abundance and leptin (LEP) mRNA expression in fetal adipose tissue. It is not known whether such changes persist into adult life and whether they are associated with an effect on phenotype. We investigated the effect of high (240%) and low (70%) levels of recommended daily crude protein intake for beef heifers during the first and second trimesters of gestation on singleton progeny (n=68): subcutaneous (SC) adipose tissue depth at rump (P8) and rib (RF) sites from 65 until 657 days of age; plasma leptin concentrations from birth until 657 days and expression ofIGF1andIGF2, their receptors (IGF1RandIGF2R) andLEPmRNA in perirenal (PR), omental (OM) and SC adipose tissue at 680 days of age. High-protein diets during the first trimester increasedLEPandIGF1mRNA in PR of males and females, respectively, compared with low-protein diets, and decreasedIGF1RmRNA in SC of all progeny but increased RF depth of males between 552 and 657 days. High-protein diets compared with low-protein diets during the second trimester increasedIGF1RmRNA in PR and OM of all progeny;LEPmRNA in PR of males; andIGF2andIGF2RmRNA in OM of all progeny. Conversely,LEPmRNA in OM andIGF2mRNA in PR of all progeny were decreased following exposure to high- compared with low-protein diets during the second trimester. Heifer diet during gestation has permanent sex- and depot-specific effects on the expression of adipogenic and adipocytokine genes and offspring adiposity.


Metabolism ◽  
1984 ◽  
Vol 33 (3) ◽  
pp. 200-207 ◽  
Author(s):  
Jean Peret ◽  
AndréC. Bach ◽  
Brigitte Delhomme ◽  
Brigitte Bois-Joyeux ◽  
Marc Chanez ◽  
...  

2010 ◽  
Vol 88 (5) ◽  
pp. 1626-1641 ◽  
Author(s):  
O. Sarr ◽  
I. Louveau ◽  
C. Kalbe ◽  
C. C. Metges ◽  
C. Rehfeldt ◽  
...  

2007 ◽  
Vol 9 (6) ◽  
pp. 472-478 ◽  
Author(s):  
Peter M. Clifton ◽  
Jennifer Keogh

1926 ◽  
Vol 67 (1) ◽  
pp. 101-107
Author(s):  
Henry Jackson ◽  
Margaret D. Riggs

1993 ◽  
Vol 264 (6) ◽  
pp. G1057-G1065 ◽  
Author(s):  
C. Moundras ◽  
C. Remesy ◽  
C. Demigne

The aim of the present study was to evaluate the effect of changes in dietary protein level on overall availability of amino acids for tissues. For this purpose, rats were adapted to diets containing various concentrations of casein (7.5, 15, 30, and 60%) and were sampled either during the postprandial or postabsorptive period. In rats fed the protein-deficient diet, glucogenic amino acids (except threonine) tended to accumulate in plasma, liver, and muscles. In rats fed high-protein diets, the hepatic balance of glucogenic amino acids was markedly enhanced and their liver concentrations were consistently depressed. This response was the result of a marked induction of amino acid catabolism (a 45-fold increase of liver threonine-serine dehydratase activity was observed with the 60% casein diet). The muscle concentrations of threonine, serine, and glycine underwent changes parallel to plasma and liver concentrations, and a significant reduction of glutamine was observed. During the postabsorptive period, adaptation to high-protein diets resulted in a sustained catabolism of most glucogenic amino acids, which accentuated the drop in their concentrations (especially threonine) in all the compartments studied. The time course of metabolic adaptation from a 60 to a 15% casein diet has also been investigated. Adaptation of alanine and glutamine metabolism was rapid, whereas that of threonine, serine, and glycine was delayed and required 7-11 days. This was paralleled by a relatively slow decay of liver threonine-serine dehydratase (T-SDH) activity in contrast to the rapid adaptation of pyruvate kinase activity after refeeding a high-carbohydrate diet.(ABSTRACT TRUNCATED AT 250 WORDS)


2012 ◽  
Vol 590 (8) ◽  
pp. 2035-2049 ◽  
Author(s):  
Hugues Magne ◽  
Isabelle Savary-Auzeloux ◽  
Carole Migné ◽  
Marie-Agnès Peyron ◽  
Lydie Combaret ◽  
...  

2008 ◽  
Vol 92 (2) ◽  
pp. 219-220 ◽  
Author(s):  
T. C. Hall ◽  
O. M. Mahony ◽  
L. M. Freeman ◽  
E. A. Rozanski

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