Metaphor comprehension deficit in schizophrenia with reference to the hypothesis of abnormal lateralization and right hemisphere dysfunction

2014 ◽  
Vol 44 ◽  
pp. 1-14 ◽  
Author(s):  
Madhushree Chakrabarty ◽  
Sharmila Sarkar ◽  
Amita Chatterjee ◽  
Malay Ghosal ◽  
Prathama Guha ◽  
...  
Keyword(s):  
Right Hemisphere ◽  
Metaphor Comprehension ◽  
Right Hemisphere Dysfunction ◽  
Comprehension Deficit

Magnetoencephalographic evidence of early right hemisphere overactivation during metaphor comprehension in schizophrenia

2015 ◽  
Vol 52 (6) ◽  
pp. 770-781 ◽  
Author(s):  
Maor Zeev-Wolf ◽  
Miriam Faust ◽  
Yechiel Levkovitz ◽  
Yuval Harpaz ◽  
Abraham Goldstein
Keyword(s):  
Right Hemisphere ◽  
Metaphor Comprehension

The right hemisphere: neuropsychological functions

1986 ◽  
Vol 64 (5) ◽  
pp. 693-704 ◽  
Author(s):  
Kenneth M. Heilman ◽  
Dawn Bowers ◽  
Edward Valenstein ◽  
Robert T. Watson
Keyword(s):  
Emotional Disorders ◽  
Right Hemisphere ◽  
Content Type ◽  
Reading And Writing ◽  
The Past ◽  
Right Hemisphere Damage ◽  
Right Hemisphere Dysfunction ◽  
Neuropsychological Functions ◽  
The Right ◽  
Fine Print

✓ In the past two to three decades, clinicians and neuroscientists have been studying the functions of the right hemisphere. Neither hemisphere seems to be dominant in the absolute sense. Each appears to be specialized and is dominant for different functions. However, most functions require the cooperation of both hemispheres. When one is damaged, the other can often compensate for the damaged one. Lesions of the left hemisphere are associated with language (speech, reading, and writing) and praxic disorders, and lesions of the right hemisphere can result in visuospatial, attentional, and emotional disorders. The authors review some of the major behavioral disorders associated with right hemisphere dysfunction and concentrate on three major types of disorders — visuospatial, attentional, and emotional. Although not all the behavioral defects associated with right hemisphere damage can be subgrouped under these three types, they are the ones most often associated with right hemisphere lesions.

Right Hemisphere Dysfunction in Subjects With Attention-Deficit Disorder With and Without Hyperactivity

1997 ◽  
Vol 12 (2) ◽  
pp. 107-115 ◽  
Author(s):  
Carmen García-Sánchez ◽  
Armando Estévez-González ◽  
Emilia Suárez-Romero ◽  
Carme Junqué
Keyword(s):  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Right Hemisphere ◽  
Right Hemisphere Dysfunction

Emotion processing in Alzheimer's disease

1997 ◽  
Vol 3 (5) ◽  
pp. 411-419 ◽  
Author(s):  
NICOLE L. CADIEUX ◽  
KEVIN W. GREVE
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Right Hemisphere ◽  
Emotion Processing ◽  
Processing System ◽  
Affective Stimuli ◽  
Task Instructions ◽  
Right Hemisphere Dysfunction ◽  
Processing Deficits

Emotion processing deficits may have an important effect on the quality of life of Alzheimer's disease (AD) patients and their families, yet there are few studies in this area and little is known about the cause of such deficits in AD. This study sought to determine if some AD patients have a disruption in a specific right hemisphere emotion processing system, and to determine if the processing of emotional facial expression is more vulnerable to the pathology of AD than is the perception of emotional prosody. It was specifically hypothesized that patients with greater right hemisphere dysfunction (low spatial AD patients) would be impaired on emotion processing tasks relative to those with predominantly left hemisphere dysfunction (low verbal AD patients). Both groups showed impairment on emotion processing tasks but for different reasons. The low verbal patients performed poorly on the affect processing measures because they had difficulty comprehending and/or remembering the task instructions. In contrast, low spatial AD patients have emotion processing deficits that are independent of language and/or memory and may be due to a more general visuoperceptual deficit that affects the perception of static but not dynamic affective stimuli. (JINS, 1997, 3, 411–419.)

scholarly journals Spoken Sentence Comprehension in Aphasia: Event-related Potential Evidence for a Lexical Integration Deficit

1997 ◽  
Vol 9 (1) ◽  
pp. 39-66 ◽  
Author(s):  
Tamara Swaab ◽  
Colin Brown ◽  
Peter Hagoort
Keyword(s):  
Sentence Comprehension ◽  
Right Hemisphere ◽  
Sentence Context ◽  
Event Related Potential ◽  
Oddball Paradigm ◽  
Final Word ◽  
N400 Effect ◽  
Lexical Information ◽  
Preceding Sentence ◽  
Comprehension Deficit

In this study the N400 component of the event-related potential was used to investigate spoken sentence understanding in Broca's and Wernicke's aphasics. The aim of the study was to determine whether spoken sentence comprehension problems in these patients might result from a deficit in the on-line integration of lexical information. Subjects listened to sentences spoken at a normal rate. In half of these sentences, the meaning of the final word of the sentence matched the semantic specifications of the preceding sentence context. In the other half of the sentences, the sentence-final word was anomalous with respect to the preceding sentence context. The N400 was measured to the sentence-final words in both conditions. The results for the aphasic patients (n = 14) were analyzed according to the severity of their comprehension deficit and compared to a group of 12 neurologically unimpaired age-matched controls, as well as a group of 6 nonaphasic patients with a lesion in the right hemisphere. The nonaphasic brain damaged patients and the aphasic patients with a light comprehension deficit (high comprehenders, n = 7) showed an N400 effect that was comparable to that of the neurologically unimpaired subjects. In the aphasic patients with a moderate to severe comprehension deficit (low comprehenders, n = 7), a reduction and delay of the N400 effect was obtained. In addition, the P300 component was measured in a classical oddball paradigm, in which subjects were asked to count infrequent low tones in a random series of high and low tones. No correlation was found between the occurrence of N400 and P300 effects, indicating that changes in the N400 results were related to the patients' language deficit. Overall, the pattern of results was compatible with the idea that aphasic patients with moderate to severe comprehension problems are impaired in the integration of lexical information into a higher order representation of the preceding sentence context.

Lateralisation abnormalities in obsessive–compulsive disorder: a line bisection study

2015 ◽  
Vol 27 (4) ◽  
pp. 242-247 ◽  
Author(s):  
Naren Prahlada Rao ◽  
Rashmi Arasappa ◽  
Nalini Narayana Reddy ◽  
Ganesan Venkatasubramanian ◽  
Janardhan Reddy Y.C.
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Right Hemisphere ◽  
Line Bisection ◽  
Analysis Of Covariance ◽  
Severe Illness ◽  
Cerebral Asymmetry ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Right Hemisphere Dysfunction ◽  
Brain Structure And Function

ObjectiveAsymmetry in brain structure and function is implicated in the pathogenesis of psychiatric disorders. Although right hemisphere abnormality has been documented in obsessive–compulsive disorder (OCD), cerebral asymmetry is rarely examined. Therefore, in this study, we examined anomalous cerebral asymmetry in OCD patients using the line bisection task.MethodsA total of 30 patients with OCD and 30 matched healthy controls were examined using a reliable and valid two-hand line bisection (LBS) task. The comparative profiles of LBS scores were analysed using analysis of covariance.ResultsPatients with OCD bisected significantly less number of lines to the left and had significant rightward deviation than controls, indicating right hemisphere dysfunction. The correlations observed in this study suggest that those with impaired laterality had more severe illness at baseline.ConclusionsThe findings of this study indicate abnormal cerebral lateralisation and right hemisphere dysfunction in OCD patients.

Delirium and Right-Hemisphere Dysfunction in Cognitively Impaired Older Persons

1996 ◽  
Vol 8 (3) ◽  
pp. 373-382 ◽  
Author(s):  
John R. Mach ◽  
Vivian Kabat ◽  
Doug Olson ◽  
Michael Kuskowski
Keyword(s):  
Risk Factor ◽  
Right Hemisphere ◽  
Memory Loss ◽  
Depression Scale ◽  
Indirect Evidence ◽  
Controlled Study ◽  
Cognitively Impaired ◽  
Retrospective Case ◽  
Right Hemisphere Dysfunction ◽  
History Of

Cognitive impairment has been repeatedly shown to be a delirium risk factor. Much indirect evidence suggests that right-hemisphere dysfunction plays a particularly important role. This retrospective, case-controlled study, from a 148-patient memory loss clinic database, compared neuropsychological measures of hemispheric function in cognitively impaired elderly veterans with and without a history of delirium. Eleven study subjects had a history compatible with DSM-III-R criteria for delirium. Controls selected from the same database had no known history of delirium and were matched for Mini-Mental State Examination scores and Geriatric Depression Scale scores. Compared to the controls, subjects with a history of delirium had significantly lower scores on Object Assembly and Visual Reproduction (p < .05), tests that are predominantly right-hemisphere dependent. There were no significant differences in left-hemisphere measures. It is concluded that right-hemisphere dysfunction may prove to be an important risk factor for delirium.

scholarly journals Metaphor Comprehension and Interpretation in Cleft Palate Children Aged 6–9

2017 ◽  
Vol 21 (1) ◽  
pp. 266-286
Author(s):  
Katarzyna Konopka ◽  
Ewa Pisula ◽  
Emilia Łojek ◽  
Piotr Fudalej
Keyword(s):  
Cleft Palate ◽  
Figurative Language ◽  
Right Hemisphere ◽  
Control Groups ◽  
Intelligence Scale ◽  
Metaphor Comprehension ◽  
Polish Version ◽  
Test Picture ◽  
The Right ◽  
And Control

Abstract The level of metaphor comprehension and interpretation was investigated in a sample of children with cleft palate (CP), aged 6;0-8;11, and healthy controls matched with age, sex, socioeconomic status, and IQ level. The Wechsler Intelligence Scale for Children - Revised (WISC-R) was used to evaluate the children’s cognitive functioning, and the metaphor tests from a modified version of the Right Hemisphere Language Battery - Polish version (RHLB-PL) were used to assess comprehension of figurative language. The CP and control groups differed significantly in Verbal IQ values and in performance in the Vocabulary test, Comprehension test, Picture Metaphor Explanation test, and Written Metaphor Explanation test. In both metaphor explanation tests, children with CP gave fewer responses than controls. The results suggest no differences between children with CP and controls in understanding figurative language, although they point to weaker performance in communicating responses and producing statements in the CP children group.

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