scholarly journals Gender, smoking, body size, and aneurysm geometry influence the biomechanical rupture risk of abdominal aortic aneurysms as estimated by finite element analysis

2017 ◽  
Vol 65 (4) ◽  
pp. 1014-1021.e4 ◽  
Author(s):  
Moritz Lindquist Liljeqvist ◽  
Rebecka Hultgren ◽  
Antti Siika ◽  
T. Christian Gasser ◽  
Joy Roy
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Body Size ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Rupture Risk ◽  
Element Analysis ◽  
Abdominal Aortic

scholarly journals Finite Element Analysis of Abdominal Aortic Aneurysms: Predicted Rupture Risk Correlates With Aortic Wall Histology in Individual Patients

2014 ◽  
Vol 21 (4) ◽  
pp. 556-564 ◽  
Author(s):  
Philipp Erhart ◽  
Caspar Grond-Ginsbach ◽  
Maani Hakimi ◽  
Felix Lasitschka ◽  
Susanne Dihlmann ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Aortic Wall ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Rupture Risk ◽  
Element Analysis ◽  
Abdominal Aortic

scholarly journals On the Relative Impact of Intraluminal Thrombus Heterogeneity on Abdominal Aortic Aneurysm Mechanics

2019 ◽  
Vol 141 (11) ◽  
Author(s):  
Joseph R. Leach ◽  
Evan Kao ◽  
Chengcheng Zhu ◽  
David Saloner ◽  
Michael D. Hope
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Aneurysm Rupture ◽  
Aortic Aneurysms ◽  
Patient Specific ◽  
Rupture Risk ◽  
Intraluminal Thrombus ◽  
Element Analysis ◽  
Aneurysm Wall ◽  
Abdominal Aortic

Intraluminal thrombus (ILT) is present in the majority of abdominal aortic aneurysms (AAA) of a size warranting consideration for surgical or endovascular intervention. The rupture risk of AAAs is thought to be related to the balance of vessel wall strength and the mechanical stress caused by systemic blood pressure. Previous finite element analyses of AAAs have shown that ILT can reduce and homogenize aneurysm wall stress. These works have largely considered ILT to be homogeneous in mechanical character or have idealized a stiffness distribution through the thrombus thickness. In this work, we use magnetic resonance imaging (MRI) to delineate the heterogeneous composition of ILT in 7 AAAs and perform patient–specific finite element analysis under multiple conditions of ILT layer stiffness disparity. We find that explicit incorporation of ILT heterogeneity in the finite element analysis is unlikely to substantially alter major stress analysis predictions regarding aneurysm rupture risk in comparison to models assuming a homogenous thrombus, provided that the maximal ILT stiffness is the same between models. Our results also show that under a homogeneous ILT assumption, the choice of ILT stiffness from values common in the literature can result in significantly larger variations in stress predictions compared to the effects of thrombus heterogeneity.

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