scholarly journals Identification of MicroRNAs Associated With Abdominal Aortic Aneurysms and Peripheral Arterial Disease

2015 ◽  
Vol 62 (3) ◽  
pp. 786
Author(s):  
P.W. Stather ◽  
N. Sylvius ◽  
D.A. Sidloff
2015 ◽  
Vol 102 (7) ◽  
pp. 755-766 ◽  
Author(s):  
P. W. Stather ◽  
N. Sylvius ◽  
D. A. Sidloff ◽  
N. Dattani ◽  
A. Verissimo ◽  
...  

Angiology ◽  
2015 ◽  
Vol 67 (4) ◽  
pp. 307-308
Author(s):  
Kosmas I. Paraskevas ◽  
Ian M. Nordon ◽  
Stephen J. Baxter ◽  
Clifford P. Shearman ◽  
Mike J. Phillips

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Hassan Al-Thani ◽  
Ayman El-Menyar

We aimed to evaluate the frequency, clinical profiles and outcomes of abdominal aortic aneurysms (AAA), and their association with coronary artery disease (CAD) in a small country with high cardiovascular burden. Methods. Data were collected for all adult patients who underwent abdominal computed tomography scans at Hamad General Hospital in Qatar between 2004 and 2008. Results. Out of 13,115 screened patients for various reasons, 61 patients (0.5%) had abdominal aneurysms. The majority of AAA patients were male (82%) with a mean age of 67 ± 12 years. The incidence of AAA substantially increased with age reaching up to 5% in patients >80 yrs. Hypertension was the most prevalent risk factor for AAA followed by smoking, dyslipidemia, renal impairment, and diabetes mellitus. CAD and peripheral arterial disease (PAD) were observed in 36% and 13% of AAA patients, respectively. There were no significant correlations between CAD or PAD and site and size of AAA. Conclusion. This is the largest study in our region that describes the epidemiology of AAA with concomitant CAD. As the mortality rate is quite high in this high risk population, routine screening for AAA in CAD patients and vice versa needs further studies for proper risk stratification.


PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0139887 ◽  
Author(s):  
Marianne Beckmann ◽  
Vincenzo Jacomella ◽  
Malcom Kohler ◽  
Mario Lachat ◽  
Amr Salem ◽  
...  

2018 ◽  
Vol 38 (5) ◽  
pp. 366-373 ◽  
Author(s):  
Satu Mäkelä ◽  
Markku Asola ◽  
Henrik Hadimeri ◽  
James Heaf ◽  
Maija Heiro ◽  
...  

BackgroundPeripheral arterial disease and vascular calcifications contribute significantly to the outcome of dialysis patients. The aim of this study was to evaluate the prognostic role of severity of abdominal aortic calcifications and peripheral arterial disease on outcome of peritoneal dialysis (PD) patients using methods easily available in everyday clinical practice.MethodsWe enrolled 249 PD patients (mean age 61 years, 67% male) in this prospective, observational, multicenter study from 2009 to 2013. The abdominal aortic calcification score (AACS) was assessed using lateral lumbar X ray, and the ankle-brachial index (ABI) using a Doppler device.ResultsThe median AACS was 11 (range 0 – 24). In 58% of the patients, all 4 segments of the abdominal aorta showed deposits, while 19% of patients had no visible deposits (AACS 0). Ankle-brachial index was normal in 49%, low (< 0.9) in 17%, and high (> 1.3) in 34% of patients. Altogether 91 patients (37%) died during the median follow-up of 46 months. Only 2 patients (5%) with AACS 0 died compared with 50% of the patients with AACS ≥ 7 ( p < 0.001). The adjusted hazard ratio for all-cause mortality was 4.85 (95% confidence interval [CI] 1.94 – 24.46) for aortic calcification (AACS ≥ 7), 2.14 for diabetes (yes/no), 0.93 for albumin (per 1 g/L), and 1.04 for age (per year). A low or high ABI were not independently associated with mortality.ConclusionsSevere aortic calcification was a strong predictor of all-cause mortality in PD patients. The evaluation of aortic calcifications by lateral X ray is a simple method that allows the identification of high-risk patients.


2013 ◽  
Vol 7 (6) ◽  
pp. 472-474 ◽  
Author(s):  
Kosmas I. Paraskevas ◽  
Dimitri P. Mikhailidis ◽  
Athanasios D. Giannoukas

The prevalence of abdominal aortic aneurysms (AAAs) and AAA-related deaths are steadily declining in some countries as a result of the reduction in smoking rates. It was thus suggested that screening programs that do not target high-risk populations are likely to have very low AAA detection rates. However, this may not apply to other countries that do not exhibit similar reductions in smoking rates. It was assumed that by using the U.S. Preventive Services Task Force screening criteria (men 65-75 years with smoking history) less than 30% of AAAs would be captured. A more extensive scoring system that includes additional risk factors such as the presence of carotid artery or peripheral arterial disease, obesity, hypertension, and so on, may identify almost 90% of AAAs. This article discusses this and other issues on screening, prevention, and treatment of AAAs.


Chirurgia ◽  
2017 ◽  
Vol 30 (6) ◽  
Author(s):  
Nabil A. Al-Zoubi ◽  
Nawaf J. Al-Shatnawi ◽  
Tagleb S. Mazaheh ◽  
Emad M. Hijazi ◽  
Abdel R. Al-Manasra

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