scholarly journals VESS16. Predictive Ability of the SVS Lower Extremity Guidelines Committee Wound, Ischemia, and Foot Infection (WIfI) Scale for First-time Revascularizations

2015 ◽  
Vol 61 (6) ◽  
pp. 24S-25S ◽  
Author(s):  
Jeremy D. Darling ◽  
John C. McCallum ◽  
Peter A. Soden ◽  
Dominique B. Buck ◽  
Sara L. Zettervall ◽  
...  
2017 ◽  
Vol 65 (3) ◽  
pp. 695-704 ◽  
Author(s):  
Jeremy D. Darling ◽  
John C. McCallum ◽  
Peter A. Soden ◽  
Raul J. Guzman ◽  
Mark C. Wyers ◽  
...  

2015 ◽  
Vol 61 (2) ◽  
pp. 575-576
Author(s):  
Jeremy D. Darling ◽  
John C. McCallum ◽  
Yifan Meng ◽  
Peter Soden ◽  
Sara Zettervall ◽  
...  

2009 ◽  
Vol 11 (3) ◽  
pp. 304-309 ◽  
Author(s):  
Giannina L. Garcés-Ambrossi ◽  
Matthew J. McGirt ◽  
Roger Samuels ◽  
Daniel M. Sciubba ◽  
Ali Bydon ◽  
...  

Object Although postsurgical neurological outcomes in patients with tethered cord syndrome (TCS) are well known, the rate and development of neurological improvement after first-time tethered cord release is incompletely understood. The authors reviewed their institutional experience with the surgical management of adult TCS to assess the time course of symptomatic improvement, and to identify the patient subgroups most likely to experience improvement of motor symptoms. Methods The authors retrospectively reviewed 29 consecutive cases of first-time adult tethered cord release. Clinical symptoms of pain and motor and urinary dysfunction were evaluated at 1 and 3 months after surgery, and then every 6 months thereafter. Rates of improvement in pain and motor or urinary dysfunction over time were identified, and presenting factors associated with improvement of motor symptoms were assessed using a multivariate survival analysis (Cox model). Results The mean patient age was 38 ± 13 years. The causes of TCS included lipomyelomeningocele in 3 patients (10%), tight filum in 3 (10%), lumbosacral lipoma in 4 (14%), intradural tumor in 3 (10%), previous lumbosacral surgery in 2 (7%), and previous repair of myelomeningocele in 14 (48%). The mean ± SD duration of symptoms before presentation was 5 ± 7 months. Clinical presentation included diffuse pain/parasthesias in both lower extremities in 13 patients (45%), or perineal distribution in 18 (62%), lower extremity weakness in 17 (59%), gait difficulties in 17 (59%), and bladder dysfunction in 14 (48%). Laminectomy was performed in a mean of 2.5 ± 0.7 levels per patient, and 9 patients (30%) received duraplasty. At 18 months postoperatively, 47% of patients had improved urinary symptoms, 69% had improved lower extremity weakness and gait, and 79% had decreased painful dysesthesias. Median time to symptomatic improvement was least for pain (1 month), then motor (2.3 months), and then urinary symptoms (4.3 months; p = 0.04). In patients demonstrating improvement, 96% improved within 6 months of surgery. Only 4% improved beyond 1-year postoperatively. In a multivariate analysis, the authors found that patients who presented with asymmetrical lower extremity weakness (p = 0.0021, hazard ratio 5.7) or lower extremity hyperreflexia (p = 0.037, hazard ratio = 4.1) were most likely to experience improvement in motor symptoms. Conclusions In the authors' experience, pain and motor and urinary dysfunction improve postoperatively in the majority of patients. The rate of symptomatic improvement was greatest for pain resolution, followed by motor, and then urinary improvement. Patients who experienced improvement in any symptom had done so by 6 months after tethered cord release. Patients with asymmetrical motor symptoms or lower extremity hyperreflexia at presentation were most likely to experience improvements in motor symptoms. These findings may help guide patient education and surgical decision-making.


2018 ◽  
Vol 67 (2) ◽  
pp. e26-e27
Author(s):  
Jeremy D. Darling ◽  
Thomas F.X. O'Donnell ◽  
Sarah E. Deery ◽  
Giap H. Vu ◽  
Anthony V. Norman ◽  
...  

Animals ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 710 ◽  
Author(s):  
Yunxiang Zhao ◽  
Ning Gao ◽  
Jian Cheng ◽  
Saeed El-Ashram ◽  
Lin Zhu ◽  
...  

Artificial insemination (AI) has been used globally as a routine technology in the swine production industry. However, genetic parameters and genomic prediction accuracy of semen traits have seldom been reported. In this study, we estimated genetic parameters and conducted genomic prediction for five types of sperm morphology abnormalities in a large Duroc boar population. The estimated heritability of the studied traits ranged from 0.029 to 0.295. In the random cross-validation scenario, the predictive ability ranged from 0.212 to 0.417 for genomic best linear unbiased prediction (GBLUP) and from 0.249 to 0.565 for single-step GBLUP (ssGBLUP). In the forward prediction scenario, the predictive ability ranged from 0.069 to 0.389 for GBLUP and from 0.085 to 0.483 for ssGBLUP. In conclusion, the studied sperm morphology abnormalities showed moderate to low heritability. Both GBLUP and ssGBLUP showed comparative predictive abilities of breeding values, and ssGBLUP outperformed GBLUP under many circumstances in respect to predictive ability. To our knowledge, this is the first time that the genetic parameters and genomic predictive ability of these traits were reported in such a large Duroc boar population.


2018 ◽  
Vol 68 (5) ◽  
pp. 1455-1464.e1 ◽  
Author(s):  
Jeremy D. Darling ◽  
Thomas F.X. O'Donnell ◽  
Sarah E. Deery ◽  
Anthony V. Norman ◽  
Giap H. Vu ◽  
...  

2015 ◽  
Vol 25 (1) ◽  
pp. 182-192 ◽  
Author(s):  
Cailbhe Doherty ◽  
Chris Bleakley ◽  
Jay Hertel ◽  
Brian Caulfield ◽  
John Ryan ◽  
...  

2015 ◽  
Vol 50 (6) ◽  
pp. 651-664 ◽  
Author(s):  
Cailbhe Doherty ◽  
Chris M. Bleakley ◽  
Jay Hertel ◽  
Brian Caulfield ◽  
John Ryan ◽  
...  

Context No researchers, to our knowledge, have investigated the immediate postinjury-movement strategies associated with acute first-time lateral ankle sprain (LAS) as quantified by center of pressure (COP) and kinematic analyses during performance of the Star Excursion Balance Test (SEBT). Objective To analyze the kinematic and COP patterns of a group with acute first-time LAS and a noninjured control group during performance of the SEBT. Design Case-control study. Setting University biomechanics laboratory. Patients or Other Participants A total of 81 participants with acute first-time LAS (53 men, 28 women; age = 23.22 ± 4.93 years, height = 1.73 ± 0.09 m, mass = 75.72 ± 13.86 kg) and 19 noninjured controls (15 men, 4 women; age = 22.53 ± 1.68 years, height = 1.74 ± 0.08 m, mass = 71.55 ± 11.31 kg). Intervention Participants performed the anterior (ANT), posterolateral (PL), and posteromedial (PM) reach directions of the SEBT. Main Outcome Measure(s) We assessed 3-dimensional kinematics of the lower extremity joints and associated fractal dimension (FD) of the COP path during performance of the SEBT. Results The LAS group had decreased normalized reach distances in the ANT, PL, and PM directions when compared with the control group on their injured (ANT: 58.16% ± 6.86% versus 64.86% ± 5.99%; PL: 85.64% ± 10.62% versus 101.14% ± 8.39%; PM: 94.89% ± 9.26% versus 107.29 ± 6.02%) and noninjured (ANT: 60.98% ± 6.74% versus 64.76% ± 5.02%; PL: 88.95% ± 11.45% versus 102.36% ± 8.53%; PM: 97.13% ± 8.76% versus 106.62% ± 5.78%) limbs (P < .01). This observation was associated with altered temporal sagittal-plane kinematic profiles throughout each reach attempt and at the point of maximum reach (P < .05). This result was associated with a reduced FD of the COP path for each reach direction on the injured limb only (P < .05). Conclusions Acute first-time LAS was associated with bilateral deficits in postural control, as evidenced by the bilateral reduction in angular displacement of the lower extremity joints and reduced reach distances and FD of the COP path on the injured limb during performance of the SEBT.


1989 ◽  
Vol 79 (4) ◽  
pp. 159-174 ◽  
Author(s):  
MS Downey ◽  
AS Banks

An updated and thorough review of the gastrocnemius equinus deformity and its surgical correction is presented. For the first time, a long-term retrospective study documents the overall improvement in the symptoms and architecture of the lower extremity and foot following gastrocnemius recession. Additionally, numerous associated concerns and the surgical procedure are examined retrospectively.


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