scholarly journals The impact of postoperative discontinuation or continuation of chronic statin therapy on cardiac outcome after major vascular surgery

2007 ◽  
Vol 46 (5) ◽  
pp. 1081
Author(s):  
Y. Le Manach ◽  
G. Godet ◽  
P. Coriat
Keyword(s):  
Vascular Surgery ◽  
Statin Therapy ◽  
Cardiac Outcome ◽  
The Impact ◽  
Major Vascular Surgery

The Impact of Postoperative Discontinuation or Continuation of Chronic Statin Therapy on Cardiac Outcome After Major Vascular Surgery

2007 ◽  
Vol 104 (6) ◽  
pp. 1326-1333 ◽  
Author(s):  
Yannick Le Manach ◽  
Gilles Godet ◽  
Pierre Coriat ◽  
Claire Martinon ◽  
Mich??le Bertrand ◽  
...  
Keyword(s):  
Vascular Surgery ◽  
Statin Therapy ◽  
Cardiac Outcome ◽  
The Impact ◽  
Major Vascular Surgery

scholarly journals Intensity of Statin Therapy in Relation to Myocardial Ischemia, Troponin T Release, and Clinical Cardiac Outcome in Patients Undergoing Major Vascular Surgery

2007 ◽  
Vol 50 (17) ◽  
pp. 1649-1656 ◽  
Author(s):  
Harm H.H. Feringa ◽  
Olaf Schouten ◽  
Stefanos E. Karagiannis ◽  
Jasper Brugts ◽  
Abdou Elhendy ◽  
...  
Keyword(s):  
Myocardial Ischemia ◽  
Vascular Surgery ◽  
Statin Therapy ◽  
Troponin T ◽  
Cardiac Outcome ◽  
Major Vascular Surgery

scholarly journals Impact of Preoperative Statin Therapy on Adverse Postoperative Outcomes in Patients Undergoing Vascular Surgery

2011 ◽  
Vol 114 (1) ◽  
pp. 98-104 ◽  
Author(s):  
Yannick Le Manach ◽  
Cristina Ibanez Esteves ◽  
Michelle Bertrand ◽  
Jean Pierre Goarin ◽  
Marie-Hélène Fléron ◽  
...  
Keyword(s):  
Adverse Events ◽  
Vascular Surgery ◽  
Statin Therapy ◽  
Organ Dysfunction ◽  
Multiple Organ Dysfunction Syndrome ◽  
Surgical Complications ◽  
Odds Ratio ◽  
Multiple Organ ◽  
Multiple Organ Dysfunction ◽  
Major Vascular Surgery

Background Chronic statin therapy is associated with reduced postoperative mortality. Renal and cardiovascular benefits have been described, but the effect of chronic statin therapy on postoperative adverse events has not yet been explored. Methods In this observational study involving 1,674 patients undergoing aortic reconstruction, we prospectively assessed chronic statin therapy compared with no statin therapy, with regard to serious outcomes, by propensity score and multivariable methods. Results In propensity-adjusted multivariable logistic regression (c-index: 0.83), statins were associated with an almost threefold reduction in the risk of death in patients undergoing major vascular surgery (odds ratio: 0.40; 95% CI: 0.28-0.59) and an almost twofold reduction in the risk of postoperative myocardial infarction (odds ratio: 0.52; 95% CI: 0.38-0.71). Likewise, the use of chronic statin therapy was associated with a reduced risk of postoperative stroke and renal failure. Statins did not significantly reduce the risk of pneumonia, multiple organ dysfunction syndrome, and surgical complications; however, in the case of postoperative multiple organ dysfunction syndrome (odds ratio: 0.34; 95% CI: 0.12-0.94) and surgical complications (odds ratio: 0.39; 95% CI: 0.17-0.86), reduced mortality was observed. Conclusions Chronic statin therapy was associated with a reduction in all cardiac and vascular outcomes after major vascular surgery. Furthermore, in major adverse events, such as multiple organ dysfunction syndrome and surgical complications, statins were also associated with decreased mortality.

scholarly journals 1037 Early Detection and Management of Preoperative Anaemia in An Elective Vascular Surgery Cohort

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
S Tanna ◽  
J Walker
Keyword(s):  
Vascular Surgery ◽  
Adverse Outcomes ◽  
Major Surgery ◽  
Surgical Patient ◽  
Post Intervention ◽  
Early Management ◽  
The Mean ◽  
The Impact ◽  
Major Vascular Surgery ◽  
Preoperative Anaemia

Abstract Introduction Iron deficiency anaemia is the most common cause of anaemia in the surgical population. Patients receiving transfusions during major surgery encounter more adverse outcomes compared to those that do not, indicating the early management of pre-operative anemia is likely to reduce major surgical patient morbidity and mortality. Previous studies have demonstrated that 33% of patients undergoing major vascular surgery operations are anaemic (haemaglobin, Hb, <130g/L). Aim We aim to reduce the proportion of anaemic patients undergoing major vascular surgery by 50%. Method A point-of-care HemoCue machine was used to measure Hb in patients who were referred for elective major surgery in 11 vascular clinics. Patients with Hb < 130g/L were prescribed a 1-month course of Ferrous Sulfate (200mg TDS), and a letter was sent to their GP requesting iron function tests. Post-intervention Hb levels were rechecked following the preoperative anaesthetics review. Results 11 patients were referred for major surgery, of which 4 were identified as anaemic (36%). The mean Hb concentration was 121.3g/L, which increased to 137.3g/L following oral iron therapy. The mean duration of follow up was 36 days (range 0-94 days). Conclusions The implementation of a HemoCue machine to identify and manage preoperative anaemia was successful in our pilot study. Further work should include full integration of our pathway into current vascular clinics without student support. This will enable evaluation of the impact of our intervention on a wider scale.

Perioperative Statin Therapy and Renal Outcomes After Major Vascular Surgery: A Propensity-Based Analysis

2008 ◽  
Vol 22 (2) ◽  
pp. 210-216 ◽  
Author(s):  
Daryl J. Kor ◽  
Michael J. Brown ◽  
Remzi Iscimen ◽  
Daniel R. Brown ◽  
Francis X. Whalen ◽  
...  
Keyword(s):  
Vascular Surgery ◽  
Statin Therapy ◽  
Renal Outcomes ◽  
Major Vascular Surgery
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