scholarly journals Anatomic factors associated with acute endograft collapse after Gore TAG treatment of thoracic aortic dissection or traumatic rupture

2007 ◽  
Vol 45 (4) ◽  
pp. 655-661 ◽  
Author(s):  
Bart E. Muhs ◽  
Ron Balm ◽  
Geoffrey H. White ◽  
Hence J.M. Verhagen
Keyword(s):  
Aortic Dissection ◽  
Traumatic Rupture ◽  
Thoracic Aortic Dissection ◽  
Factors Associated ◽  
Endograft Collapse

Ultrasound diagnosis of dissecting thoracic aortic aneurysms: procedure with a handheld device and a video-illustrated case

2021 ◽  
Vol 51 (1) ◽  
pp. 10-15
Author(s):  
Kenneth V Iserson ◽  
Sri Devi Jagjit ◽  
Balram Doodnauth
Keyword(s):  
Aortic Dissection ◽  
Correct Diagnosis ◽  
Signs And Symptoms ◽  
Aortic Aneurysms ◽  
Thoracic Aortic Aneurysms ◽  
Handheld Device ◽  
Thoracic Aortic Dissection ◽  
Threatening Condition ◽  
Life Threatening ◽  
Handheld Ultrasound

Acute thoracic aortic dissection is an uncommon, although not rare, life-threatening condition. With protean signs and symptoms that often suggest more common cardiac or pulmonary conditions, it can be difficult to diagnose. Ultrasound has proven useful in making the correct diagnosis. This case demonstrates that training gained using standard ultrasound machines can be easily and successfully adapted to newer handheld ultrasound devices. The examination technique using the handheld device is illustrated with photos and a video.

scholarly journals Altered DNA methylation pattern reveals epigenetic regulation of Hox genes in thoracic aortic dissection and serves as a biomarker in disease diagnosis

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Peiru Liu ◽  
Jing Zhang ◽  
Duo Du ◽  
Dandan Zhang ◽  
Zelin Jin ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Aortic Dissection ◽  
Epigenetic Regulation ◽  
Heart Development ◽  
Type A ◽  
Methylation Pattern ◽  
Healthy Controls ◽  
Global Methylation ◽  
Thoracic Aortic Dissection

Abstract Background Thoracic aortic dissection (TAD) is a severe disease with limited understandings in its pathogenesis. Altered DNA methylation has been revealed to be involved in many diseases etiology. Few studies have examined the role of DNA methylation in the development of TAD. This study explored alterations of the DNA methylation landscape in TAD and examined the potential role of cell-free DNA (cfDNA) methylation as a biomarker in TAD diagnosis. Results Ascending aortic tissues from TAD patients (Stanford type A; n = 6) and healthy controls (n = 6) were first examined via whole-genome bisulfite sequencing (WGBS). While no obvious global methylation shift was observed, numerous differentially methylated regions (DMRs) were identified, with associated genes enriched in the areas of vasculature and heart development. We further confirmed the methylation and expression changes in homeobox (Hox) clusters with 10 independent samples using bisulfite pyrosequencing and quantitative real-time PCR (qPCR). Among these, HOXA5, HOXB6 and HOXC6 were significantly down-regulated in TAD samples relative to controls. To evaluate cfDNA methylation pattern as a biomarker in TAD diagnosis, cfDNA from TAD patients (Stanford type A; n = 7) and healthy controls (n = 4) were examined by WGBS. A prediction model was built using DMRs identified previously from aortic tissues on methylation data from cfDNA. Both high sensitivity (86%) and specificity (75%) were achieved in patient classification (AUC = 0.96). Conclusions These findings showed an altered epigenetic regulation in TAD patients. This altered epigenetic regulation and subsequent altered expression of genes associated with vasculature and heart development, such as Hox family genes, may contribute to the loss of aortic integrity and TAD pathogenesis. Additionally, the cfDNA methylation in TAD was highly disease specific, which can be used as a non-invasive biomarker for disease prediction.

scholarly journals Detection of acute thoracic aortic dissection with D-dimer

2007 ◽  
Vol 24 (12) ◽  
pp. 846-847 ◽  
Author(s):  
C. VanderLinden ◽  
J. Jones ◽  
M. Brown
Keyword(s):  
Aortic Dissection ◽  
Thoracic Aortic Dissection ◽  
D Dimer

Association of Left Ventricular Hypertrophy and Aortic Dilation in Patients with Acute Thoracic Aortic Dissection

Angiology ◽  
2001 ◽  
Vol 52 (7) ◽  
pp. 447-455 ◽  
Author(s):  
Diana Iarussi ◽  
Aurelio Caruso ◽  
Maurizio Galderisi ◽  
Franco Enrico Covino ◽  
Giovanni Dialetto ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Aortic Dissection ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Aortic Dilation ◽  
Thoracic Aortic Dissection

The inadvertent administration of anticoagulants to ED patients ultimately diagnosed with thoracic aortic dissection

2005 ◽  
Vol 23 (4) ◽  
pp. 439-442 ◽  
Author(s):  
Daniel P. Davis ◽  
Karun Grossman ◽  
Danielle C. Kiggins ◽  
Gary M. Vilke ◽  
Theodore C. Chan
Keyword(s):  
Aortic Dissection ◽  
Thoracic Aortic Dissection

scholarly journals Expression of platelet-derived growth factor B is upregulated in patients with thoracic aortic dissection

2018 ◽  
Vol 68 (6) ◽  
pp. 3S-13S ◽  
Author(s):  
Weixin Meng ◽  
Shangdian Liu ◽  
Dandan Li ◽  
Zonghong Liu ◽  
Hui Yang ◽  
...  
Keyword(s):  
Growth Factor ◽  
Aortic Dissection ◽  
Platelet Derived Growth Factor ◽  
Factor B ◽  
Thoracic Aortic Dissection
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