scholarly journals Short-term effects of cycle and treadmill training on exercise tolerance in peripheral arterial disease

2006 ◽  
Vol 44 (1) ◽  
pp. 119-127 ◽  
Author(s):  
Bradley Sanderson ◽  
Christopher Askew ◽  
Ian Stewart ◽  
Philip Walker ◽  
Harry Gibbs ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Exercise Tolerance ◽  
Arterial Disease ◽  
Treadmill Training ◽  
Short Term ◽  
Peripheral Arterial ◽  
Short Term Effects

scholarly journals Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease

2011 ◽  
Vol 110 (6) ◽  
pp. 1582-1591 ◽  
Author(s):  
Aarti A. Kenjale ◽  
Katherine L. Ham ◽  
Thomas Stabler ◽  
Jennifer L. Robbins ◽  
Johanna L. Johnson ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Exercise Tolerance ◽  
Near Infrared ◽  
Arterial Disease ◽  
No Production ◽  
Open Label ◽  
Hypoxic Conditions ◽  
Peripheral Arterial ◽  
Plasma Nitrite ◽  
And Function

Peripheral arterial disease (PAD) results in a failure to adequately supply blood and oxygen (O2) to working tissues and presents as claudication pain during walking. Nitric oxide (NO) bioavailability is essential for vascular health and function. Plasma nitrite (NO2−) is a marker of vascular NO production but may also be a protected circulating “source” that can be converted to NO during hypoxic conditions, possibly aiding perfusion. We hypothesized that dietary supplementation of inorganic nitrate in the form of beetroot (BR) juice would increase plasma NO2−concentration, increase exercise tolerance, and decrease gastrocnemius fractional O2extraction, compared with placebo (PL). This was a randomized, open-label, crossover study. At each visit, subjects ( n = 8) underwent resting blood draws, followed by consumption of 500 ml BR or PL and subsequent blood draws prior to, during, and following a maximal cardiopulmonary exercise (CPX) test. Gastrocnemius oxygenation during the CPX was measured by near-infrared spectroscopy. There were no changes from rest for [NO2−] (152 ± 72 nM) following PL. BR increased plasma [NO2−] after 3 h (943 ± 826 nM; P ≤ 0.01). Subjects walked 18% longer before the onset of claudication pain (183 ± 84 s vs. 215 ± 99 s; P ≤ 0.01) and had a 17% longer peak walking time (467 ± 223 s vs. 533 ± 233 s; P ≤ 0.05) following BR vs. PL. Gastrocnemius tissue fractional O2extraction was lower during exercise following BR (7.3 ± 6.2 vs. 10.4 ± 6.1 arbitrary units; P ≤ 0.01). Diastolic blood pressure was lower in the BR group at rest and during CPX testing ( P ≤ 0.05). These findings support the hypothesis that NO2−-related NO signaling increases peripheral tissue oxygenation in areas of hypoxia and increases exercise tolerance in PAD.

FACTORS LIMITING UPPER AND LOWER-LIMB EXERCISE TOLERANCE IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE.

2003 ◽  
Vol 35 (Supplement 1) ◽  
pp. S39
Author(s):  
J M. Saxton ◽  
I Zwierska ◽  
J S. Male ◽  
S Choksy ◽  
A G. Pockley ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Lower Limb ◽  
Exercise Tolerance ◽  
Arterial Disease ◽  
Lower Limb Exercise ◽  
Peripheral Arterial ◽  
Limb Exercise

The Effect of Short-Term Treatment with Simvastatin on Renal Function in Patients with Peripheral Arterial Disease

Angiology ◽  
2004 ◽  
Vol 55 (1) ◽  
pp. 53-62 ◽  
Author(s):  
Fahed Youssef ◽  
Prakash Gupta ◽  
Alexander M. Seifalian ◽  
Fiona Myint ◽  
Dimitri P. Mikhailidis ◽  
...  
Keyword(s):  
Renal Function ◽  
Peripheral Arterial Disease ◽  
Arterial Disease ◽  
Term Treatment ◽  
Short Term ◽  
Short Term Treatment ◽  
Peripheral Arterial

Poster 457 Comparison of Calf Exercise and Treadmill Training in Peripheral Arterial Disease

PM&R ◽  
2012 ◽  
Vol 4 ◽  
pp. S346-S346 ◽  
Author(s):  
Kaly Kao ◽  
Sung Choi ◽  
Grant Etnyre ◽  
Stephen F. Figoni ◽  
Charles F. Kunkel ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Arterial Disease ◽  
Treadmill Training ◽  
Calf Exercise ◽  
Peripheral Arterial

scholarly journals The effect of treadmill training on endothelial function and walking abilities in patients with peripheral arterial disease

2014 ◽  
Vol 64 (2) ◽  
pp. 145-151 ◽  
Author(s):  
Rafał Januszek ◽  
Piotr Mika ◽  
Anita Konik ◽  
Tomasz Petriczek ◽  
Roman Nowobilski ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Endothelial Function ◽  
Arterial Disease ◽  
Treadmill Training ◽  
Peripheral Arterial
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