scholarly journals A monoclonal antibody against cytokine-induced neutrophil chemoattractant attenuates injury in the small intestine in a model of ruptured abdominal aortic aneurysm

2004 ◽  
Vol 39 (5) ◽  
pp. 1104-1111 ◽  
Author(s):  
Ebenezar M Mbachu ◽  
Lazar V Klein ◽  
Barry B Rubin ◽  
Thomas F Lindsay
Keyword(s):  
Monoclonal Antibody ◽  
Small Intestine ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Ruptured Abdominal Aortic Aneurysm ◽  
Abdominal Aortic

A CD18 monoclonal antibody reduces multiple organ injury in a model of ruptured abdominal aortic aneurysm

1999 ◽  
Vol 277 (1) ◽  
pp. H172-H182 ◽  
Author(s):  
A. J. Boyd ◽  
B. B. Rubin ◽  
P. M. Walker ◽  
A. Romaschin ◽  
T. B. Issekutz ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Abdominal Aortic Aneurysm Repair ◽  
Multiple Organ ◽  
Organ Injury ◽  
Ruptured Abdominal Aortic Aneurysm ◽  
Abdominal Aortic ◽  
Aneurysm Repair ◽  
Pulmonary Permeability

The role of CD18 antibody (anti-CD18) in remote and local injury in a model of ruptured abdominal aortic aneurysm repair was investigated. Rats were divided into sham, shock, clamp, and shock + clamp groups. Shock + clamp animals received anti-CD18 or a control monoclonal antibody. One hour of hemorrhagic shock was followed by 45 min of supramesenteric aortic clamping. Intestinal and pulmonary permeability to125I-labeled albumin was determined. Myeloperoxidase (MPO) activity, F2-isoprostane levels, and transaminases were also measured. Only shock + clamp resulted in statistically significant increases in pulmonary and intestinal permeability, which were associated with significant increases in MPO activity and F2-isoprostane levels. Treatment with anti-CD18 significantly decreased intestinal and pulmonary permeability in shock + clamp animals. These reductions were associated with significantly reduced intestinal and hepatic MPO activity and pulmonary F2-isoprostane levels and reduced alanine and aspartate aminotransferase levels; however, anti-CD18 had no effect on intestinal or hepatic F2-isoprostane levels or on pulmonary MPO activity. These results suggest CD18-dependent and -independent mechanisms of local and remote organ injury in this model of ruptured abdominal aortic aneurysm.

Relaparotomies after ruptured abdominal aortic aneurysm repair

1994 ◽  
Vol 8 (3) ◽  
pp. 342-345 ◽  
Author(s):  
F.C.W. Slootmans ◽  
J.A. van der Vliet ◽  
H.H.M. Reinaerts ◽  
S.F.S. van Roye ◽  
F.G.M. Buskens
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Abdominal Aortic Aneurysm Repair ◽  
Ruptured Abdominal Aortic Aneurysm ◽  
Abdominal Aortic ◽  
Aneurysm Repair ◽  
Aortic Aneurysm Repair

Ruptured Abdominal Aortic Aneurysm and Horseshoe Kidney: Isthmus Sectioning By Endo GIA

2019 ◽  
Vol 53 (7) ◽  
pp. 599-601
Author(s):  
Pagliariccio Gabriele ◽  
Gatta Emanuele ◽  
Carlo Grilli Cicilioni ◽  
Schiavon Sara ◽  
Carbonari Luciano
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Horseshoe Kidney ◽  
Ruptured Abdominal Aortic Aneurysm ◽  
Aortic Graft ◽  
Urinary Leakage ◽  
Aortic Neck ◽  
Abdominal Aortic ◽  
Open Surgical Approach ◽  
Graft Reconstruction

Introduction: A 90-year-old patient was admitted with a hemorrhagic shock from a huge ruptured abdominal aortic aneurysm with an unfavourable infrarenal aortic neck and a horseshoe kidney (HSK). Report: We decided on an open surgical approach: the HSK isthmus was sectioned with an Endo GIA 45 mm, and we performed a suprarenal aortic cross-clamping and an aortic graft reconstruction. Postoperatively, no urinary leakage was detected, and renal function showed no impairment. The patient died on the 10th postoperative day from pneumonia. Conclusion: We believe that the sectioning of the HSK isthmus with Endo GIA is a fast and simple maneouvre.

scholarly journals Emergency endovascular treatment for ruptured abdominal aortic aneurysm and the risk of spinal cord ischemia

2005 ◽  
Vol 42 (4) ◽  
pp. 608-614 ◽  
Author(s):  
Noud Peppelenbosch ◽  
Philippe W.M. Cuypers ◽  
Anco C. Vahl ◽  
Frank Vermassen ◽  
Jacob Buth
Keyword(s):  
Spinal Cord ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Endovascular Treatment ◽  
Spinal Cord Ischemia ◽  
Ruptured Abdominal Aortic Aneurysm ◽  
Abdominal Aortic
Sign in / Sign up

Export Citation Format

Share Document