scholarly journals Designing A Discrete Choice Experiment To Measure Patient Preferences And Willingness-To-Pay For Targeted Therapies For Colorectal Cancer In Singapore

2016 ◽  
Vol 19 (7) ◽  
pp. A891 ◽  
Author(s):  
XY Wong ◽  
JW Chia ◽  
MH Chew ◽  
WS Tan ◽  
HL Wee
Keyword(s):  
Colorectal Cancer ◽  
Willingness To Pay ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Targeted Therapies ◽  
Patient Preferences ◽  
Choice Experiment

A discrete choice experiment to examine preferences and willingness to pay for prophylactic granulocyte colony-stimulating factors (G-CSF) in previously treated breast cancer patients.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e17509-e17509 ◽  
Author(s):  
Phaedra Johnson ◽  
Tim Bancroft ◽  
Richard L. Barron ◽  
Jason C. Legg ◽  
Xiaoyan Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Willingness To Pay ◽  
Cancer Patients ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Patient Preferences ◽  
Choice Experiment ◽  
Risk Of Infection ◽  
Breast Cancer Patients ◽  
Patient Centered

e17509 Background: As patient-centered care becomes more prominent, a better understanding of patient preferences and tradeoffs amongst treatment alternatives and outcomes is needed. This study used a discrete choice experiment to examine the preferences and willingness to pay for prophylactic G-CSF to decrease the incidence of chemotherapy (CT)-induced febrile neutropenia in breast cancer patients who previously received CT. Methods: An online survey was developed with 16 paired treatment choice scenarios comparing 3 alternative G-CSF options (11 versus 1 or 6 versus 1 injections per CT cycle) with a follow-up “no treatment” option. Each scenario had 4 attributes: risk of disruption to CT schedule due to neutropenia, risk of infection requiring hospitalization, frequency of G-CSF administration, and total out-of-pocket (OOP) cost for G-CSF during a CT cycle. Patients’ preferences and willingness to pay (as OOP cost) were estimated using logistic regression. Results: Patients’ (n = 296) preferred G-CSF options with the lowest OOP costs, the fewest injections, and improved outcomes (lowest risk of disruption to CT schedule and lowest risk of infection requiring hospitalization). In the context of this discrete choice experiment, OOP costs and risk of disruption to CT schedule were the most important attributes to patients; risk of infection requiring hospitalization and frequency of G-CSF administration affected patients’ choice of G-CSF option to a smaller but similar degree. Patients were willing to pay OOP $1,076 per cycle to reduce the risk of disrupting the CT schedule from high to low, $884 per cycle to reduce the risk of developing an infection requiring hospitalization from 24% (high) to 7% (low), and $851 and $667 per cycle to decrease the number of G-CSF injections per cycle from 11 to 1 and 6 to 1, respectively. Conclusions: With a current focus on patient-centered approaches in decision-making, physicians need to consider patient preferences when making decisions about therapy, including supportive care agents.

scholarly journals Patient preferences for management of high blood pressure in the UK: a discrete choice experiment

2019 ◽  
Vol 69 (686) ◽  
pp. e629-e637 ◽  
Author(s):  
Benjamin Fletcher ◽  
Lisa Hinton ◽  
Richard McManus ◽  
Oliver Rivero-Arias
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Willingness To Pay ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Patient Preferences ◽  
Choice Experiment ◽  
Models Of Care ◽  
Self Management ◽  
The Uk

BackgroundWith a variety of potentially effective hypertension management options, it is important to determine how patients value different models of care, and the relative importance of factors in their decision-making process.AimTo explore patient preferences for the management of hypertension in the UK.Design and settingOnline survey of patients who have hypertension in the UK including an unlabelled discrete choice experiment (DCE).MethodA DCE was developed to assess patient preferences for the management of hypertension based on four attributes: model of care, frequency of blood pressure (BP) measurement, reduction in 5-year cardiovascular risk, and costs to the NHS. A mixed logit model was used to estimate preferences, willingness-to-pay was modelled, and a scenario analysis was conducted to evaluate the impact of changes in attribute levels on the uptake of different models of care.ResultsOne hundred and sixty-seven participants completed the DCE (aged 61.4 years, 45.0% female, 82.0% >5 years since diagnosis). All four attributes were significant in choice (P<0.05). Reduction in 5-year cardiovascular risk was the main driver of patient preference as evidenced in the scenario and willingness-to-pay analyses. GP management was significantly preferred over self-management. Patients preferred scenarios with more frequent BP measurement, and lower costs to the NHS.ConclusionParticipants had similar preferences for GP management, pharmacist management, and telehealth, but a negative preference for self-management. When introducing new models of care for hypertension to patients, discussion of the potential benefits in terms of risk reduction should be prioritised to maximise uptake.

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