scholarly journals PND49 The Measurement of Quality of Life in Children With Cystic Fibrosis With Using Russian Version of Health Utility Index (HUI) Questionnaire

2012 ◽  
Vol 15 (7) ◽  
pp. A554
Author(s):  
Y. Gorinova ◽  
O. Simonova ◽  
I. Vinyarskaya ◽  
M. Samsonova ◽  
V. Chernikov
Keyword(s):  
Quality Of Life ◽  
Cystic Fibrosis ◽  
Health Utility Index ◽  
Health Utility ◽  
Russian Version ◽  
Utility Index

scholarly journals Validation of Russian Version of Health Utility Index Questionnare in Children with Cystic Fibrosis

2014 ◽  
Vol 17 (7) ◽  
pp. A731
Author(s):  
O. Simonova ◽  
Y. Gorinova ◽  
I. Vinyarskaya ◽  
V. Chernikov
Keyword(s):  
Cystic Fibrosis ◽  
Health Utility Index ◽  
Health Utility ◽  
Russian Version ◽  
Utility Index

scholarly journals Obesity and Preference-Weighted Quality of Life of Ethnically Diverse Middle School Children: The HEALTHY Study

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
R. P. Treviño ◽  
T. H. Pham ◽  
S. L. Edelstein
Keyword(s):  
Quality Of Life ◽  
Health Utility Index ◽  
Ethnically Diverse ◽  
Tanner Stage ◽  
Health Utility ◽  
Sixth Grade ◽  
Normal Weight ◽  
Family History Of Diabetes ◽  
Utility Index

To date, studies examining the relation between body mass index percentile (BMI%) categories and health-related quality of life (QOL) measurements have not reported preference-weighted scores among ethnically diverse children. We report the associations between BMI% categories and preference-weighted scores among a large cohort of ethnically diverse sixth grade children who participated in the HEALTHY school-based type 2 diabetes risk factor prevention study. Health Utility Index 2 (HUI2) and Health Utility Index 3 (HUI3) and the feeling thermometer (FT) were the preference-weighted QOL instruments used to measure student’s preference scores. Of 6358 consented students, 4979 (78.3%) had complete QOL, height, weight, and covariate data. Mean (SD) preference scores were 0.846 (0.160), 0.796 (0.237), and 0.806 (0.161) for the HUI2, HUI3, and FT, respectively. After adjusting for age, sex, blood glucose and insulin, Tanner stage, race/ethnicity, family history of diabetes, and educational attainment, children with severe obesity (>99%) had significantly lower preference scores compared to normal weight on all three instruments (HUI2P=0.013; HUI3P=0.025; and FTP<0.001). Obese and severe obese categories were significantly associated with lower HUI2 functional ratings in the mobility domain and with lower HUI3 functional ratings in the speech domain.

Quality of life in cochlear implantees: Comparing utility values obtained through the Medical Outcome Study Short-Form Survey-6D and the Health Utility Index Mark 3

2014 ◽  
Vol 124 (11) ◽  
pp. 2586-2590 ◽  
Author(s):  
Christoph Arnoldner ◽  
Vincent Y. Lin ◽  
Richard Bresler ◽  
Alexandra Kaider ◽  
Jafri Kuthubutheen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Health Utility Index ◽  
Health Utility ◽  
Medical Outcome Study ◽  
Outcome Study ◽  
Medical Outcome ◽  
Utility Index ◽  
Health Utility Index Mark

TO011HEALTH UTILITY BUT NOT UREMIC TOXINS ARE ASSOCIATED WITH ONE YEAR MORTALITY IN HD PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Wim Van Biesen ◽  
Amaryllis Van Craenenbroeck ◽  
Daniel Abramowicz ◽  
Holvoet Els ◽  
Veys Nic ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nutritional Status ◽  
Association Studies ◽  
Objective Assessment ◽  
Health Utility Index ◽  
Health Utility ◽  
Uremic Toxins ◽  
Serum Concentrations ◽  
Prospective Longitudinal

Abstract Background and Aims Patient centred care is progressively gaining importance. Standardized outcomes should take into account patient relevant outcomes, such as mortality and quality of life. It is unknown whether the health utility index EQ5D, an objective assessment of quality of life, is associated with mortality in haemodialysis patients. Serum concentrations of different uremic toxins have been associated with survival. We intended to explore whether EQ5D rather than concentrations of representative uraemic toxins (UT) was associated with mortality. Method Prospective longitudinal multicentric cohort study of all haemodialysis patients at 5 representative dialysis centres in Flanders. Total and free concentrations of representative uraemic toxins indoxyl sulfate (IxS), p-cresyl sulfate (pCS), p-cresyl glucuronide (pCG), indole acetic acid (IAA), 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid (CMPF), hippuric acid (HA) and uric acid (UA) were determined at baseline. Mini Nutritional Assessment (MNA) and EQ5D were assessed by dedicated nurses. Mortality was assessed from administrative or medical records. A Cox regression model was built, both fixed and as conditional forward including clinical parameters, MNA, EQ5D and serum concentrations of the different uraemic toxins. Results 216 prevalent patients (62%male, age 67.2 ± 15.7) all on high flux haemodialysis were included. Over the observation period, 59 patients (27%) died. Health utility as assessed by EQ5D was 0.69±0.28; perceived health by visual analogue scale (VAS) (0-100) was 59.6±18.6. Adjusting for age, gender and MNA score, free but not total concentrations of IxS, pCS and IAA and EQ5D score were associated with overall survival in the forced entry model. However, neither in the fixed entry, the forward or backward model were serum concentrations of uraemic toxins retained, and only age, gender, BMI, EQ5D and VAS were consistently associated with survival. Conclusion Measures of health utility, such as EQ5D, and quality of life, such as a simple VAS score, are more predictive of survival in patients on regular haemodialysis than serum concentrations of a panel of relevant uraemic toxins. Health utility and QoL are thus not only directly relevant to patients, but also indirectly through an association with improved survival. The concept of dialysis adequacy has been challenged over the last decade, mainly because it was focusing on small solute clearance. Different authors reported that concentrations of middle molecular and protein bound solutes were more representative. In our study, free but not total solute concentrations were associated with survival. However, adjusting additionally for health utility and/or health perception and/or assessment of nutritional status abolishes this association. Studies assessing interventions to enhance solute removal should not only include solute concentrations as outcome, but also consider EQ5D, VAS and nutritional status as important outcomes to enhance patient centeredness of their findings.

scholarly journals The Benefit of Endovascular Thrombectomy for Stroke on Functional Outcome Is Sustained at 12 Months

2021 ◽  
pp. 81-86
Author(s):  
Balaki Parameshwaran ◽  
Dennis Cordato ◽  
Mark Parsons ◽  
Andrew Cheung ◽  
Nathan Manning ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Functional Outcome ◽  
Health Utility Index ◽  
Health Utility ◽  
Functional Independence ◽  
Place Of Residence ◽  
Endovascular Thrombectomy ◽  
Comprehensive Stroke Center ◽  
Stroke Center

<b><i>Background and Purpose:</i></b> The short-term benefits of endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) have been widely documented, yet there is limited evidence to show that this is sustained in the long term. We aimed to determine whether the benefit of EVT on functional outcome at 3 months is maintained at 12 months and the factors correlating with functional independence and quality of life. <b><i>Methods:</i></b> Data for analysis came from a prospective registry of consecutive patients undergoing EVT at a single Comprehensive Stroke Center (Oct 2018–Sep 2019). A phone interview was conducted for 12-month patient outcomes. Functional outcome was assessed by the modified Rankin Scale (mRS). Quality of life was determined by return to usual place of residence, work, or driving and calculation of a health utility index using the European Quality of Life-5 Dimensions questionnaire (EQ-5D-3L). <b><i>Results:</i></b> Of the 151 patients who underwent EVT during the study period, 12-month follow-up was available for 145 (96%). At 12 months, 44% (<i>n</i> = 64) of patients were functionally independent (mRS 0–2) compared to 48% at 3 months. Mortality at 12 months was 26% compared to 17% at 3 months. Significant predictors of functional independence at 12 months were younger age and lower baseline National Institutes of Health Stroke Scale. Better quality of life significantly correlated with return to usual place of residence and driving. <b><i>Conclusion:</i></b> Three-month functional independence was sustained at 12 months, indicating that EVT remains beneficial for patients with AIS in the longer term.

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