scholarly journals PMD19 Multiple Daily Injection Therapy (MDI) Versus Durable Insulin Pump Therapy in Type II Diabetics: A Breakeven Analysis

2012 ◽  
Vol 15 (4) ◽  
pp. A65 ◽  
Author(s):  
G. David ◽  
J. Shafiroff ◽  
A. Saulnier ◽  
C. Gunnarsson
Keyword(s):  
Insulin Pump ◽  
Injection Therapy ◽  
Insulin Pump Therapy ◽  
Daily Injection ◽  
Type Ii ◽  
Pump Therapy ◽  
Multiple Daily Injection ◽  
Type Ii Diabetics ◽  
Breakeven Analysis

scholarly journals Insulin pump therapy in children with diabetes mellitus: practice of Krasnoyarsk Krai

2012 ◽  
Vol 15 (4) ◽  
pp. 46-60
Author(s):  
Tatiana Evgen'evna Taranushenko ◽  
Viktoriya Nikolaevna Panfilova ◽  
Oksana Alekseevna Terent'eva ◽  
Nadezhda Dmitrievna Koreshkova ◽  
Maria Nikolaevna Petrova
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Pump ◽  
Laboratory Data ◽  
Severe Hypoglycemia ◽  
Insulin Pump Therapy ◽  
Daily Injection ◽  
Krasnoyarsk Krai ◽  
Pump Therapy ◽  
Multiple Daily Injection ◽  
Injection Regimen

Aim. To summarize practical experience of insulin pump therapy (IPT) in child population of Krasnoyarsk and to assess its efficacy for treatment of type 1 diabetes mellitus (T1DM) in paediatrics. Materials and Methods. We performed a comparative analysis of clinical and laboratory data from 48 children with T1DM prior to and after 6-12 months of IPT. Results. IPT yielded fourfold decrease in complaints of hyperglycemia and labile glycemia without concurrent increase in reports of severe hypoglycemia.  We observed a trend for lowering of mean HbA1c levels, where 65% of patients showed positive dynamics in comparison with the period of multiple daily injection regimen. Interestingly, after 6-12 months of IPT, insulin requirement dropped in most patients. Conclusion. Our data support clinical efficiency and safety of IPT, as well as superiority of this treatment over multiple daily injection regimen. We conclude that IPT is a treatment of choice for children with T1DM.

Automated Bolus Calculators and Connected Insulin Pens: A Smart Combination for Multiple Daily Injection Insulin Therapy

2021 ◽  
pp. 193229682110626
Author(s):  
David T Ahn
Keyword(s):  
Health Care Professionals ◽  
Insulin Pump ◽  
Insulin Pump Therapy ◽  
Daily Injection ◽  
Regulatory Oversight ◽  
Pump Therapy ◽  
Multiple Daily Injection ◽  
Insulin Pens ◽  
Bolus Insulin ◽  
Glycemic Outcomes

Although automated bolus calculators (ABCs) have become a mainstay in insulin pump therapy, they have not achieved similar levels of adoption by persons with diabetes (PWD) using multiple daily injections of insulin (MDI). Only a small number of blood glucose meters (BGMs) have incorporated ABC functionality and the proliferation of unregulated ABC smartphone apps raised safety concerns and eventually led to Food and Drug Administration (FDA)–mandated regulatory oversight for these types of apps. With the recent introduction of smartphone-connected insulin pens, manufacturer-supported companion ABC apps may offer an ideal solution for PWD and health care professionals that reduces errors of mental math when calculating bolus insulin dosing, increases the quality of diabetes data reporting, and improves glycemic outcomes.

scholarly journals Baseline Predictors of A1C Reduction in Adults Using Sensor-Augmented Pump Therapy or Multiple Daily Injection Therapy: The STAR 3 Experience

2011 ◽  
Vol 13 (6) ◽  
pp. 601-606 ◽  
Author(s):  
John B. Buse ◽  
George Dailey ◽  
Andrew A. Ahmann ◽  
Richard M. Bergenstal ◽  
Jennifer B. Green ◽  
...  
Keyword(s):  
Injection Therapy ◽  
Daily Injection ◽  
Pump Therapy ◽  
Multiple Daily Injection

Complications With Insulin Pump Therapy vs Insulin Injection Therapy—Reply

JAMA ◽  
2018 ◽  
Vol 319 (5) ◽  
pp. 503
Author(s):  
Beate Karges ◽  
Elisabeth Binder ◽  
Joachim Rosenbauer
Keyword(s):  
Insulin Pump ◽  
Insulin Injection ◽  
Injection Therapy ◽  
Insulin Pump Therapy ◽  
Pump Therapy

scholarly journals Use of insulin pump therapy is associated with reduced hospital-days in the long-term: a real-world study of 48,756 pediatric patients with type 1 diabetes

2020 ◽  
Author(s):  
Marie Auzanneau ◽  
Beate Karges ◽  
Andreas Neu ◽  
Thomas Kapellen ◽  
Stefan A. Wudy ◽  
...  
Keyword(s):  
Insulin Pump ◽  
Injection Therapy ◽  
Insulin Pump Therapy ◽  
Pump Therapy ◽  
Pediatric Diabetes ◽  
Acute Complications ◽  
Hospital Days

AbstractIn pediatric diabetes, insulin pump therapy is associated with less acute complications but inpatient pump education may lead to more hospital days. We investigated the number of hospital days associated with pump vs. injection therapy between 2009 and 2018 in 48,756 patients with type 1 diabetes < 20 years of age from the German Diabetes Prospective Follow-up Registry (DPV). Analyses were performed separately for hospitalizations at diagnosis (hierarchical linear models adjusted for sex, age, and migration), and for hospitalizations in the subsequent course of the disease (hierarchical Poisson models stratified by sex, age, migration, and therapy switch). At diagnosis, the length of hospital stay was longer with pump therapy than with injection therapy (mean estimate with 95% CI: 13.6 [13.3–13.9] days vs. 12.8 [12.5–13.1] days, P < 0.0001), whereas during the whole follow-up beyond diagnosis, the number of hospital days per person-year (/PY) was higher with injection therapy than with pump therapy (4.4 [4.1–4.8] vs. 3.9 [3.6–4.2] days/PY), especially for children under 5 years of age (4.9 [4.4–5.6] vs. 3.5 [3.1–3.9] days/PY).Conclusions: Even in countries with hospitalizations at diabetes diagnosis of longer duration, the use of pump therapy is associated with a reduced number of hospital days in the long-term. What is known:• In pediatric diabetes, insulin pump therapy is associated with better glycemic control and less acute complications compared with injection therapy.• However, pump therapy implies more costs and resources for education and management.What is new:• Even in countries where pump education is predominantly given in an inpatient setting, the use of pump therapy is associated with a reduced number of hospital days in the long-term.• Lower rates of hospitalization due to acute complications during the course of the disease counterbalance longer hospitalizations due to initial pump education

scholarly journals Pharmacotherapy of type1 diabetes in children and adolescents: more than insulin?

2018 ◽  
Vol 9 (5) ◽  
pp. 157-166 ◽  
Author(s):  
Torben Biester ◽  
Olga Kordonouri ◽  
Thomas Danne
Keyword(s):  
Type 1 Diabetes ◽  
Insulin Pump ◽  
Real Life ◽  
Glucose Monitoring ◽  
Insulin Analogues ◽  
Insulin Pump Therapy ◽  
Daily Injection ◽  
Great Success ◽  
Pump Therapy

For paediatric patients with type 1 diabetes, intensified insulin therapy with either multiple daily injection or insulin pump therapy is currently the only method of treatment. To optimize this therapy, insulin analogues are fixed parts of all therapy regimens. New ultra-rapid insulins seem to be beneficial not only in adults but also in this age group. New developments in long-acting analogues have demonstrated safety and will be regular in paediatrics, we hope, soon. Furthermore, the psychosocial approach for consideration of real-life aspects becomes more the focus of therapeutic regimens and is implemented into international guidelines. Technical improvements, such as continuous glucose monitoring, particularly in combination with pump therapy, support the great success of rapid-acting analogues by reducing hypoglycaemias. Non-insulin agents such as SGLT2-inhibitors show beneficial aspects in people with type 1 diabetes. For outpatient care with these currently off-label-used drugs, special training for measurement of ketones should be imperative.

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