scholarly journals PCV112 EXTENSION OF META-ANALYSIS IN COMPARING OF FIMASARTAN WITH LOSARTAN IN BLOOD PRESSURE LOWERING EFFECT

2011 ◽  
Vol 14 (3) ◽  
pp. A53
Author(s):  
Y. Na ◽  
E.K. Lee
Keyword(s):  
Blood Pressure ◽  
Meta Analysis ◽  
Blood Pressure Lowering ◽  
Blood Pressure Lowering Effect ◽  
Lowering Effect ◽  
Pressure Lowering

scholarly journals Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Kazuhisa Sugai ◽  
Tomoyoshi Tamura ◽  
Motoaki Sano ◽  
Shizuka Uemura ◽  
Masahiko Fujisawa ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Nervous System ◽  
Parasympathetic Nervous System ◽  
Pressure Control ◽  
Hydrogen Gas ◽  
Blood Pressure Lowering ◽  
Blood Pressure Lowering Effect ◽  
Night Time ◽  
Lowering Effect ◽  
Pressure Lowering

AbstractA recent clinical study demonstrated that haemodialysis with a dialysate containing hydrogen (H2) improves blood pressure control in end-stage kidney disease. Herein, we examined whether H2 has a salutary effect on hypertension in animal models. We subjected 5/6 nephrectomised rats to inhalation of either H2 (1.3% H2 + 21% O2 + 77.7% N2) or control (21% O2 + 79% N2) gas mixture for 1 h per day. H2 significantly suppressed increases in blood pressure after 5/6 nephrectomy. The anti-hypertensive effect of H2 was also confirmed in rats in a stable hypertensive state 3 weeks after nephrectomy. To examine the detailed effects of H2 on hypertension, we used an implanted telemetry system to continuously monitor blood pressure. H2 exerted an anti-hypertensive effect not only during daytime rest, but also during night-time activities. Spectral analysis of blood pressure variability revealed that H2 improved autonomic imbalance, namely by suppressing the overly active sympathetic nervous system and augmenting parasympathetic nervous system activity; these effects co-occurred with the blood pressure-lowering effect. In conclusion, 1-h daily exposure to H2 exerts an anti-hypertensive effect in an animal model of hypertension.

Blood pressure-lowering effect of dietary (−)-epicatechin administration in L-NAME-treated rats is associated with restored nitric oxide levels

2012 ◽  
Vol 53 (10) ◽  
pp. 1894-1902 ◽  
Author(s):  
Maria C. Litterio ◽  
Grayson Jaggers ◽  
Gulcin Sagdicoglu Celep ◽  
Ana M. Adamo ◽  
Maria A. Costa ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Blood Pressure ◽  
Blood Pressure Lowering ◽  
Blood Pressure Lowering Effect ◽  
Lowering Effect ◽  
Pressure Lowering
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