The relationship between zinc intake and serum/plasma zinc concentration in pregnant and lactating women: A systematic review with dose–response meta-analyses

2012 ◽  
Vol 26 (2-3) ◽  
pp. 74-79 ◽  
Author(s):  
Victoria Hall Moran ◽  
Anna-Louise Skinner ◽  
Marisol Warthon Medina ◽  
Sujata Patel ◽  
Fiona Dykes ◽  
...  
Nutrients ◽  
2012 ◽  
Vol 4 (8) ◽  
pp. 841-858 ◽  
Author(s):  
Victoria Hall Moran ◽  
Anna-Louise Stammers ◽  
Marisol Warthon Medina ◽  
Sujata Patel ◽  
Fiona Dykes ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 1027 ◽  
Author(s):  
José C. Fernández-Cao ◽  
Marisol Warthon-Medina ◽  
Victoria H. Moran ◽  
Victoria Arija ◽  
Carlos Doepking ◽  
...  

Zinc could have a protective role against type 2 diabetes mellitus (T2DM). This systematic review and meta-analysis aimed to evaluate the association between dietary, supplementary, and total zinc intake, as well as serum/plasma and whole blood zinc concentration, and risk of T2DM. Observational studies, conducted on cases of incident diabetes or T2DM patients and healthy subjects that reported a measure of association between zinc exposure and T2DM, were selected. Random effects meta-analyses were applied to obtain combined results. Stratified meta-analyses and meta-regressions were executed to assess sources of heterogeneity, as well as the impact of covariates on the findings. From 12,136 publications, 16 studies were selected. The odds ratio (OR) for T2DM comparing the highest versus lowest zinc intake from diet was 0.87 (95% CI: 0.78–0.98). Nevertheless, no association between supplementary or total zinc intake from both diet and supplementation, and T2DM was observed. A direct relationship was found between serum/plasma zinc levels and T2DM (OR = 1.64, 95% CI: 1.25–2.14). A moderately high dietary zinc intake, in relation to the Dietary Reference Intake, could reduce by 13% the risk of T2DM, and up to 41% in rural areas. Conversely, elevated serum/plasma zinc concentration was associated with an increased risk of T2DM by 64%, suggesting disturbances in zinc homeostasis.


2013 ◽  
Vol 72 (OCE4) ◽  
Author(s):  
M. Warthon-Medina ◽  
S. Dillon ◽  
V. Hall Moran ◽  
A. L. Stammers ◽  
P. Qualter ◽  
...  

1992 ◽  
Vol 45 (3) ◽  
pp. 221-226 ◽  
Author(s):  
Hiromi ISHIDA ◽  
Masakazu KIKUCHI ◽  
Tetsuro HONGO ◽  
Tsuguyoshi SUZUKI

2016 ◽  
Vol 69 (2) ◽  
pp. 135-141 ◽  
Author(s):  
Mandy Ho ◽  
Anne-Louise M. Heath ◽  
Megan Gow ◽  
Louise A. Baur ◽  
Chris T. Cowell ◽  
...  

Background: Zinc has a critical role in metabolism and growth. This study aims to determine the effects of low-energy diets differing in macronutrient composition on zinc intake, estimated zinc bioavailability (phytate:zinc molar ratio) and plasma zinc concentration and associations between zinc status and cardiometabolic markers in obese adolescents with clinical insulin resistance (IR). Methods: Eighty-seven obese adolescents (10-17 years, body mass index z-score 2.3 ± 0.37) with clinical IR were randomized to a low-energy diet (6.0-8.0 MJ), which was either high carbohydrate or moderate carbohydrate with increased protein. Twenty-four-hour dietary recalls were collected at 6, 9 and 12 weeks. Plasma zinc concentration and cardiometabolic markers were assessed at baseline and 12 weeks. Results: Zinc intake did not differ between the 2 diet groups (p = 0.612). The high-carbohydrate group had a higher phytate intake (894 vs. 671 mg, p = 0.018) and phytate:zinc molar ratio (9.4 vs. 7.4, p = 0.009) than the increased-protein group. Plasma zinc concentration did not change from baseline in either of the diet groups, but correlated positively with zinc intake (r = 0.235, p = 0.042) and % energy from protein (r = 0.383, p = 0.001), and inversely with % energy from carbohydrate (r = -0.296, p = 0.010). Conclusions: Low energy diets for obese adolescents at risk of diabetes may need increased protein content to optimize zinc bioavailability.


2013 ◽  
Vol 57 (3) ◽  
pp. 348-355 ◽  
Author(s):  
K. Ryan Wessells ◽  
Sonja Y. Hess ◽  
Noel Rouamba ◽  
Zinewendé P. Ouédraogo ◽  
Mark Kellogg ◽  
...  

2021 ◽  
Vol 11 (4) ◽  
pp. 434
Author(s):  
Delfina Janiri ◽  
Eliana Conte ◽  
Ilaria De Luca ◽  
Maria Velia Simone ◽  
Lorenzo Moccia ◽  
...  

Background: early onset is frequent in Bipolar Disorders (BDs), and it is characterised by the occurrence of mixed states (or mixed features). In this systematic review, we aimed to confirm and extend these observations by providing the prevalence rates of mixed states/features and data on associated clinical, pharmacological and psychopathological features. Methods: following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched from inception to 9 February 2021 for all studies investigating mixed states/mixed features in paediatric BD. Data were independently extracted by multiple observers. The prevalence rates of mixed states/features for each study were calculated. Results: eleven studies were included in our review, involving a total patient population of 1365 individuals. Overall, of the patients with paediatric age BD, 55.2% had mixed states/features (95% CI 40.1–70.3). Children with mixed states/features presented with high rates of comorbidities, in particular, with Attention Deficit Hyperactivity Disorder (ADHD). Evidences regarding the psychopathology and treatment response of mixed states/features are currently insufficient. Conclusions: our findings suggested that mixed states/features are extremely frequent in children and adolescents with BD and are characterised by high levels of comorbidity. Future investigations should focus on the relationship between mixed states/features and psychopathological dimensions as well as on the response to pharmacological treatment.


PEDIATRICS ◽  
1986 ◽  
Vol 77 (1) ◽  
pp. 132-133
Author(s):  
MICHAEL H. N. GOLDEN ◽  
BARBARA E. GOLDEN

To the Editor.— Kumar and Anday1 describe three premature infants presenting with edema and hypoproteinemia—the classical signs of kwashiorkor—between 5 and 9 weeks of age. Such cases are not uncommon in developing countries. Kumar and Anday's patients had low plasma zinc concentrations (43, 37, and 42 µg/dL). On this basis the authors claim that edema and hypoproteinemia is a clinical presentation of zinc deficiency not previously reported. We reported2 a clear association between "nutritional" edema and a low plasma zinc concentration in 1979; our subsequent experience has confirmed that edema of this type is always associated with a low plasma zinc concentration, as indeed Kumar and Andays' cases demonstrate.


2011 ◽  
Vol 141 (7) ◽  
pp. 1369-1374 ◽  
Author(s):  
Grant J. Aaron ◽  
Nafissatou Ba Lo ◽  
Sonja Y. Hess ◽  
Amadou T. Guiro ◽  
Salimata Wade ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document