The tetraethylammonium salt of monensic acid—An antidote for subacute cadmium intoxication. A study using an ICR mouse model

2012 ◽  
Vol 26 (4) ◽  
pp. 279-284 ◽  
Author(s):  
Juliana Ivanova ◽  
Yordanka G. Gluhcheva ◽  
Kalina Kamenova ◽  
Sonja Arpadjan ◽  
Mariana Mitewa
Keyword(s):  
Mouse Model ◽  
Cadmium Intoxication ◽  
Icr Mouse

scholarly journals Shi Xiao San ameliorates the development of adenomyosis in an ICR mouse model

2020 ◽  
Author(s):  
Juan Ye ◽  
Xueting Cai ◽  
Dawei Wang ◽  
Furong Zhang ◽  
Zhigang Wang ◽  
...  
Keyword(s):  
Mouse Model ◽  
Icr Mouse

Osmanthus fragrans Flower Extract and Acteoside Protect Against d-Galactose-Induced Aging in an ICR Mouse Model

2016 ◽  
Vol 19 (1) ◽  
pp. 54-61 ◽  
Author(s):  
Lina Xiong ◽  
Shuqin Mao ◽  
Baiyi Lu ◽  
Jiajia Yang ◽  
Fei Zhou ◽  
...  
Keyword(s):  
Mouse Model ◽  
Osmanthus Fragrans ◽  
Flower Extract ◽  
Icr Mouse

scholarly journals Appearance of a metronidazole-resistant Helicobacter pylori strain in an infected-ICR-mouse model and difference in eradication of metronidazole-resistant and -sensitive strains.

1997 ◽  
Vol 41 (12) ◽  
pp. 2602-2605 ◽  
Author(s):  
S Matsumoto ◽  
Y Washizuka ◽  
Y Matsumoto ◽  
S Tawara ◽  
F Ikeda ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Mouse Model ◽  
Resistant Strain ◽  
Sensitive Strain ◽  
Original Strain ◽  
Antibiotic Resistant ◽  
Icr Mouse ◽  
Resistant Strains ◽  
H Pylori

We tested whether antibiotic-resistant strains appeared in vivo after the failure of treatment using the Helicobacter pylori-infected euthymic mouse model. The numbers of colonies isolated from 56 ICR mice 2 weeks after 4 days of treatment with metronidazole (3.2, 10, or 32 mg/kg of body weight) or amoxicillin (1, 3.2 or 10 mg/kg), with treatment started 4 days after H. pylori CPY2052 inoculation, were counted, and the isolated strains were tested for their sensitivities to two antibiotics to rule out the presence of antibiotic-resistant strains. One metronidazole-resistant strain was detected in a mouse treated with 10 mg of metronidazole per kg, and the MIC of metronidazole for this strain was 25 microg/ml, compared to a MIC of 1.56 microg/ml for the original strain. However, no resistant strain was detected in the amoxicillin treatment group. After the examination described above, mice challenged with a metronidazole-resistant or -sensitive strain isolated from the stomach of a mouse were treated with metronidazole or amoxicillin. The metronidazole-resistant strain was more difficult to eradicate in vivo than the sensitive strain after treatment with metronidazole but not after treatment with amoxicillin. Thus, a metronidazole-resistant H. pylori strain was selected by insufficient treatment, but no resistant strain was selected with amoxicillin. Eradication of a metronidazole-resistant H. pylori strain in vivo required a higher dosage than eradication of a metronidazole-sensitive H. pylori strain. These results may explain one of the reasons for H. pylori treatment failure.

Regenerating myofibers in tibialis anterior muscles of young ‘MDX’ mice

1987 ◽  
Vol 45 ◽  
pp. 726-727
Author(s):  
H. D. Geissinge ◽  
L.D. Rhodes
Keyword(s):  
Muscular Dystrophy ◽  
Mouse Model ◽  
Tibialis Anterior ◽  
Physiological Activity ◽  
Mdx Mice ◽  
Mode Of Inheritance

A recently discovered mouse model (‘mdx’) for muscular dystrophy in man may be of considerable interest, since the disease in ‘mdx’ mice is inherited by the same mode of inheritance (X-linked) as the human Duchenne (DMD) muscular dystrophy. Unlike DMD, which results in a situation in which the continual muscle destruction cannot keep up with abortive regenerative attempts of the musculature, and the sufferers of the disease die early, the disease in ‘mdx’ mice appears to be transient, and the mice do not die as a result of it. In fact, it has been reported that the severely damaged Tibialis anterior (TA) muscles of ‘mdx’ mice seem to display exceptionally good regenerative powers at 4-6 weeks, so much so, that these muscles are able to regenerate spontaneously up to their previous levels of physiological activity.

Mouse model of gastric infection with cytotoxin-expressing strain of Helicobacter pylori in studying of pathogenesis of chronic gastric ulcer

1998 ◽  
Vol 13 (11-s4) ◽  
pp. S178-S184 ◽  
Author(s):  
PETER KONTUREK ◽  
TOMASZ BRZOZOWSKI ◽  
STANISLAW KONTUREK ◽  
ELZBIETA KARCZEWSKA ◽  
ROBERT PAJDO ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastric Ulcer ◽  
Mouse Model ◽  
Chronic Gastric Ulcer
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