scholarly journals Pretreatment strategy with adenosine A2A receptor agonist attenuates reperfusion injury in a preclinical porcine lung transplantation model

2011 ◽  
Vol 142 (4) ◽  
pp. 887-894 ◽  
Author(s):  
Damien J. LaPar ◽  
Victor E. Laubach ◽  
Abbas Emaminia ◽  
Ivan K. Crosby ◽  
Vanessa A. Hajzus ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Reperfusion Injury ◽  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
A2a Receptor ◽  
Adenosine A2a ◽  
Transplantation Model

scholarly journals Adenosine A2A receptor agonist (regadenoson) in human lung transplantation

2020 ◽  
Vol 39 (6) ◽  
pp. 563-570 ◽  
Author(s):  
Christine L. Lau ◽  
Jared P. Beller ◽  
Joshua A. Boys ◽  
Yunge Zhao ◽  
Jennifer Phillips ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Receptor Agonist ◽  
Human Lung ◽  
Adenosine A2a Receptor ◽  
A2a Receptor ◽  
Adenosine A2a

Adenosine A2A Receptor Agonist Improves Cardiac Dysfunction From Pulmonary Ischemia-Reperfusion Injury

2005 ◽  
Vol 79 (4) ◽  
pp. 1189-1195 ◽  
Author(s):  
T. Brett Reece ◽  
Victor E. Laubach ◽  
Curtis G. Tribble ◽  
Thomas S. Maxey ◽  
Peter I. Ellman ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Cardiac Dysfunction ◽  
Receptor Agonist ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Adenosine A2a Receptor ◽  
A2a Receptor ◽  
Adenosine A2a ◽  
Pulmonary Ischemia

Effect of adenosine A2A receptor agonist (CGS) on ischemia/reperfusion injury in isolated rat liver

APOPTOSIS ◽  
2005 ◽  
Vol 10 (5) ◽  
pp. 955-962 ◽  
Author(s):  
Z. Ben-Ari ◽  
O. Pappo ◽  
J. Sulkes ◽  
Y. Cheporko ◽  
B. A. Vidne ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Rat Liver ◽  
Receptor Agonist ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Adenosine A2a Receptor ◽  
Isolated Rat Liver ◽  
A2a Receptor ◽  
Adenosine A2a ◽  
Isolated Rat

scholarly journals The Diameter of Retinal Arterioles Is Unaffected by Intravascular Administration of the Adenosine A2A Receptor Agonist Regadenoson in Normal Persons

2019 ◽  
Vol 4 (2) ◽  
pp. 1-10 ◽  
Author(s):  
Anna Dons-Jensen ◽  
Line Petersen ◽  
Hans-Erik Bøtker ◽  
Toke Bek
Keyword(s):  
Intravenous Administration ◽  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
Retinal Vessels ◽  
Adenosine Receptor Agonists ◽  
Retinal Arterioles ◽  
A2a Receptor ◽  
Adenosine A2a

Background: The neurotransmitter adenosine has been proposed to be involved in the pathogenesis of diabetic retinopathy, which may be due to the vasoactive properties of the compound. Previous studies have shown that adenosine can affect the tone of retinal arterioles in vitro to induce dilatation mediated by A2A and A2Breceptors and constriction mediated by A1 and A3 receptors. Purpose: To investigate effects of intravenous administration of the adenosine A2A receptor agonist regadenoson on the diameter of retinal vessels in vivo. Method: The diameter responses of larger retinal arterioles and venules were evaluated using the dynamic vessel analyser in 20 normal persons (age 22–31 years) after intravenous administration of the adenosine A2A receptor agonist regadenoson during exposure to systemic normoxia and hypoxia. Results: The diameter of retinal arterioles and venules increased significantly during stimulation with flickering light (p < 0.0001). Regadenoson reduced the flicker-induced dilatation of venules during normoxia (p = 0.0006), but otherwise had no effect on vessel diameters (p > 0.08 for all comparisons). Conclusions:Intravenous administration of the adenosine A2A receptor agonist regadenoson had no significant effect on the diameter of retinal arterioles. Future studies should investigate differential effects of intra- and extravascular administration of adenosine receptor agonists on retinal vessels.

Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat

2002 ◽  
Vol 438 (3) ◽  
pp. 183-188 ◽  
Author(s):  
John R Fozard ◽  
Karen M Ellis ◽  
Maria F Villela Dantas ◽  
Bruno Tigani ◽  
Lazzaro Mazzoni
Keyword(s):  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
Cgs 21680 ◽  
A2a Receptor ◽  
Adenosine A2a ◽  
Airways Inflammation

Effects of adenosine A2a receptor agonist and antagonist on hippocampal nuclear factor-kB expression preceded by MDMA toxicity

2012 ◽  
Vol 28 (1) ◽  
pp. 45-52 ◽  
Author(s):  
Fatemeh Kermanian ◽  
Mansooreh Soleimani ◽  
Alireza Ebrahimzadeh ◽  
Hossein Haghir ◽  
Mehdi Mehdizadeh
Keyword(s):  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
Nuclear Factor ◽  
A2a Receptor ◽  
Agonist And Antagonist ◽  
Adenosine A2a ◽  
Nuclear Factor Kb

ChemInform Abstract: The Synthesis and Biological Activity of a Highly Selective Adenosine A2a Receptor Agonist.

ChemInform ◽  
2010 ◽  
Vol 31 (10) ◽  
pp. no-no
Author(s):  
David R. Borcherding ◽  
Nelsen L. Lentz ◽  
Philip M. Weintraub ◽  
Mark W. Dudley ◽  
Roberta Secrest ◽  
...  
Keyword(s):  
Biological Activity ◽  
Receptor Agonist ◽  
Adenosine A2a Receptor ◽  
A2a Receptor ◽  
Adenosine A2a
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