024 The Impact of Fiera™, a Women’s Sexual Health Consumer Product, on Premenopausal Genital Engorgement as Measured by Thermography: A Proof of Concept Study

2016 ◽  
Vol 13 (6) ◽  
pp. S249-S250 ◽  
Author(s):  
S. Goldstein ◽  
I. Goldstein ◽  
L. Millheiser
2019 ◽  
Vol 28 (18) ◽  
pp. 1192-1195
Author(s):  
Dawne Garrett ◽  
Sandra Lawton

This article will explore the impact of ageing on sexual function in older women and will reflect on the social influences on women's sexual ageing, identify the effects of ageing on sexual activity, particularly on genital skin, and consider the concerns from the perspective of older women. The article will then focus on vulval skin conditions and the functional aspects of living with these conditions. Finally, the article provides a starting point for nurses to consider their own knowledge, skills and attitudes through a series of reflective questions and recommendations for those working with older women to aid the identification of issues relating to older women's sexual health and vulval skin conditions, leading to further discussions to promote genital health.


2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Clive Beggs ◽  
Valentina Tavoni ◽  
Erica Menegatti ◽  
Mirko Tessari ◽  
Riccardo Ragazzi ◽  
...  

In this proof-of-concept study the impact of central venous pressure (CVP) on internal jugular veins cross-sectional area (CSA) and blood flow time-average velocity (TAV) was evaluated in eight subjects, with the aim of understanding the drivers of the jugular venous pulse. CVP was measured using a central venous catheter while CSA variation and TAV along a cardiac cycle were acquired using ultrasound. Analysis of CVP, CSA and TAV time-series signals revealed TAV and CSA to lag behind CVP by on average 0.129 s and 0.138 s, with an inverse correlation between CSA and TAV (r= –0.316). The respective autocorrelation signals were strongly correlated (mean r=0.729-0.764), with mean CSA periodicity being 1.062 Hz. Fourier analysis revealed the frequency spectrums of CVP, TAV and CSA signals to be dominated by frequencies at approximately 1 and 2 Hz, with those >1 Hz greatly attenuated in the CSA signal. Because the autocorrelograms and periodograms of the respective signals were aligned and dominated by the same underlying frequencies, this suggested that they are more easily interpreted in the frequency domain rather than the time domain.


2020 ◽  
Author(s):  
Hector Roux de Bézieux ◽  
James Bullard ◽  
Orville Kolterman ◽  
Michael Souza ◽  
Fanny Perraudeau

BACKGROUND Novel wearable biosensors, ubiquitous smartphone ownership, and telemedicine are converging to enable new paradigms of clinical research. A new generation of continuous glucose monitoring (CGM) devices provides access to clinical-grade measurement of interstitial glucose levels. Adoption of these sensors has become widespread for the management of type 1 diabetes and is accelerating in type 2 diabetes. In parallel, individuals are adopting health-related smartphone-based apps to monitor and manage care. OBJECTIVE We conducted a proof-of-concept study to investigate the potential of collecting robust, annotated, real-time clinical study measures of glucose levels without clinic visits. METHODS Self-administered meal-tolerance tests were conducted to assess the impact of a proprietary synbiotic medical food on glucose control in a 6-week, double-blind, placebo-controlled, 2×2 cross-over pilot study (n=6). The primary endpoint was incremental glucose measured using Abbott Freestyle Libre CGM devices associated with a smartphone app that provided a visual diet log. RESULTS All subjects completed the study and mastered CGM device usage. Over 40 days, 3000 data points on average per subject were collected across three sensors. No adverse events were recorded, and subjects reported general satisfaction with sensor management, the study product, and the smartphone app, with an average self-reported satisfaction score of 8.25/10. Despite a lack of sufficient power to achieve statistical significance, we demonstrated that we can detect meaningful changes in the postprandial glucose response in real-world settings, pointing to the merits of larger studies in the future. CONCLUSIONS We have shown that CGM devices can provide a comprehensive picture of glucose control without clinic visits. CGM device usage in conjunction with our custom smartphone app can lower the participation burden for subjects while reducing study costs, and allows for robust integration of multiple valuable data types with glucose levels remotely. CLINICALTRIAL ClinicalTrials.gov NCT04424888; http://clinicaltrials.gov/ct2/show/NCT04424888.


2007 ◽  
Vol 4 (3) ◽  
pp. 656-666 ◽  
Author(s):  
Karin S. Coyne ◽  
Mary Kay Margolis ◽  
Zhanna Jumadilova ◽  
Tamara Bavendam ◽  
Elizabeth Mueller ◽  
...  

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0216657
Author(s):  
Anne Marsman ◽  
Rosan Luijcks ◽  
Catherine Vossen ◽  
Jim van Os ◽  
Richel Lousberg

2004 ◽  
Vol 23 (1) ◽  
pp. 67-74 ◽  
Author(s):  
Rebecca Campbell ◽  
Tracy Sefl ◽  
Courtney E. Ahrens

Gut ◽  
2016 ◽  
Vol 65 (5) ◽  
pp. 730-731 ◽  
Author(s):  
Shinichiro Sakata ◽  
Philip M Grove ◽  
Andrew R L Stevenson ◽  
David G Hewett

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