The Protective Effects of 17β-Estradiol on Hepatic Ischemia–Reperfusion Injury in Rat Model, Associated with Regulation of Heat-Shock Protein Expression

2007 ◽  
Vol 140 (1) ◽  
pp. 67-76 ◽  
Author(s):  
Shi-Qiang Shen ◽  
Yuan Zhang ◽  
Cheng-Long Xiong
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Rat Model ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Protective Effects ◽  
Hepatic Ischemia ◽  
Heat Shock Protein Expression ◽  
17Β Estradiol ◽  
Hepatic Ischemia Reperfusion

Protective effects of simvastatin administered in the experimental hepatic ischemia-reperfusion injury rat model

2015 ◽  
Vol 199 (2) ◽  
pp. 393-401 ◽  
Author(s):  
Fatma Emel Kocak ◽  
Aysegul Kucuk ◽  
Filiz Ozyigit ◽  
Murat Tosun ◽  
Cengiz Kocak ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Rat Model ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Protective Effects ◽  
Hepatic Ischemia ◽  
Hepatic Ischemia Reperfusion

scholarly journals Comparison of the protective effects of desflurane and propofol anesthesia in rats: a hepatic ischemia-reperfusion injury model

2013 ◽  
Vol 43 ◽  
pp. 592-598
Author(s):  
Ayca TAŞ TUNA ◽  
Cengiz Bekir DEMİREL ◽  
Yusuf ÜNAL ◽  
Aslıhan ÇAVUNT BAYRAKTAR ◽  
Demet YILMAZER ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Protective Effects ◽  
Hepatic Ischemia ◽  
Injury Model ◽  
Hepatic Ischemia Reperfusion

scholarly journals Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation

PPAR Research ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-16
Author(s):  
Jie Zhang ◽  
Ping Cheng ◽  
Weiqi Dai ◽  
Jie Ji ◽  
Liwei Wu ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Protective Effects ◽  
Hepatocyte Apoptosis ◽  
Ischemia And Reperfusion Injury ◽  
Hepatic Ischemia ◽  
Tissue Samples ◽  
Hepatic Ischemia Reperfusion ◽  
And Oxidative Stress

Hepatic ischemia and reperfusion injury is characterized by hepatocyte apoptosis, impaired autophagy, and oxidative stress. Fenofibrate, a commonly used antilipidemic drug, has been verified to exert hepatic protective effects in other cells and animal models. The purpose of this study was to identify the function of fenofibrate on mouse hepatic IR injury and discuss the possible mechanisms. A segmental (70%) hepatic warm ischemia model was established in Balb/c mice. Serum and liver tissue samples were collected for detecting pathological changes at 2, 8, and 24 h after reperfusion, while fenofibrate (50 mg/kg, 100 mg/kg) was injected intraperitoneally 1 hour prior to surgery. Compared to the IR group, pretreatment of FF could reduce the inflammatory response and inhibit apoptosis and autophagy. Furthermore, fenofibrate can activate PPAR-α, which is associated with the phosphorylation of AMPK.

scholarly journals Erratum to: Effects of everolimus on hepatic ischemia/reperfusion injury in an experimental rat model

2013 ◽  
Vol 45 (3) ◽  
pp. 184-184
Author(s):  
B.G. Demirci ◽  
M. Cindoruk ◽  
U.T. Yilmaz ◽  
M.D. Demirag ◽  
I.I. Gonul ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Rat Model ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Hepatic Ischemia ◽  
Experimental Rat Model ◽  
Hepatic Ischemia Reperfusion
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