scholarly journals Retraction notice to “The comparative study of clinical efficacy and safety of baclofen vs tolperisone in spasticity caused by spinal cord injury” [Saudi Pharm. J. 25 (2017) 655–659]

2020 ◽  
Vol 28 (5) ◽  
pp. 639
Author(s):  
Dejun Luo ◽  
Guoyong Wu ◽  
Yong Ji ◽  
Zhaoyao Zhang ◽  
Fayou He ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Comparative Study ◽  
Clinical Efficacy ◽  
Efficacy And Safety ◽  
Cord Injury ◽  
Retraction Notice ◽  
The Comparative Study

scholarly journals An observation of the clinical efficacy of combining Riluzole with mannitol and hyperbaric oxygen in treating acute spinal cord injury

2021 ◽  
Vol 37 (2) ◽  
Author(s):  
Huan-xia Li ◽  
Jing Cui ◽  
Jing-shi Fan ◽  
Jian-zhou Tong
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Hyperbaric Oxygen ◽  
Clinical Efficacy ◽  
Acute Spinal Cord Injury ◽  
Sensory Function ◽  
Control Group ◽  
Thoracolumbar Fractures ◽  
Cord Injury ◽  
Experimental Group

Objective: To examine the clinical efficacy of combining Riluzole with mannitol and hyperbaric oxygen therapy in treating thoracolumbar vertebral fracture-induced acute spinal cord injury (ASCI). Methods: From June 2015 to May 2018, 80 patients with thoracolumbar fractures and ASCI who were treated at Baoding First Central Hospital were selected. All patients underwent posterior laminectomy and screw fixation, and they were randomly divided into two groups using a random number table method. The control group received conventional postoperative treatment, while the experimental group was treated with riluzole combined with mannitol and hyperbaric oxygen on the basis of conventional treatment. The recovery of nerve function which included motor function and sensory function, and the changes of serum IL-6, CRP, BDNF, BFGF and other factors before treatment and four weeks after treatment of the two groups of patients were observed and evaluated. Results: After treatment, the motor function scores and sensory function scores of the two groups of patients were improved compared with those before treatment (p<0.05). Compared with the control group, the experimental group improved significantly, and the difference was statistically significant (p<0.05). The levels of IL-6, BDNF and NFGF in the experimental group were significantly lower than those in the control group (p<0.05). Conclusions: For patients with thoracolumbar fractures and ASCI undergoing laminar decompression and fixation, the comprehensive treatment plan of riluzole combined with mannitol and hyperbaric oxygen has certain advantages. Compared with the conventional therapy, it may significantly improve the movement and sensory functions of patients, relieve the inflammatory response of spinal cord, and promote recovery from the injury. doi: https://doi.org/10.12669/pjms.37.2.3418 How to cite this:Li H, Cui J, Fan J, Tong J. An observation of the clinical efficacy of combining Riluzole with mannitol and hyperbaric oxygen in treating acute spinal cord injury. Pak J Med Sci. 2021;37(2):---------. doi: https://doi.org/10.12669/pjms.37.2.3418 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

GM1 Ganglioside Acute Spinal Cord Injury Study II: Efficacy and Safety

Neurosurgery ◽  
1999 ◽  
Vol 45 (3) ◽  
pp. 704-704
Author(s):  
Fred Geisler ◽  
Giacinto Grieco ◽  
Frank C. Dorsey ◽  
Francesca Patarnell ◽  
Devinder Poonian ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Acute Spinal Cord Injury ◽  
Gm1 Ganglioside ◽  
Efficacy And Safety ◽  
Cord Injury

Autologous Mesenchymal Stem Cell Therapy for Spinal Cord Injury: Long Term Safety and Clinical Efficacy

2011 ◽  
Vol 3 (1) ◽  
pp. 100-106
Author(s):  
Hala Gabr ◽  
Osama Ghannam ◽  
Mohamed Reda Awad ◽  
Klaus von Wild ◽  
Wael Abo El-Kheir ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Therapy ◽  
Clinical Efficacy ◽  
Stem Cell Therapy ◽  
Mesenchymal Stem Cell Therapy ◽  
Cord Injury

scholarly journals Comparative Study of Methods for Administering Neural Stem/Progenitor Cells to Treat Spinal Cord Injury in Mice

2011 ◽  
Vol 20 (5) ◽  
pp. 727-739 ◽  
Author(s):  
Yuichiro Takahashi ◽  
Osahiko Tsuji ◽  
Gentaro Kumagai ◽  
Chikako Miyauchi Hara ◽  
Hirotaka James Okano ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Comparative Study ◽  
Progenitor Cells ◽  
Cord Injury ◽  
Neural Stem Progenitor Cells
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