Low calcium intake and inadequate vitamin D status in postmenopausal osteoporotic women

2013 ◽  
Vol 136 ◽  
pp. 175-177 ◽  
Author(s):  
José Manuel Quesada-Gómez ◽  
Manuel Diaz-Curiel ◽  
Manuel Sosa-Henriquez ◽  
Jorge Malouf-Sierra ◽  
Xavier Nogues-Solan ◽  
...  
Keyword(s):  
Vitamin D ◽  
Calcium Intake ◽  
Vitamin D Status ◽  
Low Calcium

scholarly journals Interactions between Vitamin D Status, Calcium Intake and Parathyroid Hormone Concentrations in Healthy White-Skinned Pregnant Women at Northern Latitude

Nutrients ◽  
2018 ◽  
Vol 10 (7) ◽  
pp. 916 ◽  
Author(s):  
Andrea Hemmingway ◽  
Karen O’Callaghan ◽  
Áine Hennessy ◽  
George Hull ◽  
Kevin Cashman ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Pregnant Women ◽  
Calcium Intake ◽  
Geometric Mean ◽  
Vitamin D Status ◽  
Metabolic System ◽  
Cross Sectional ◽  
The Mean ◽  
In Pregnancy

Adverse effects of low vitamin D status and calcium intakes in pregnancy may be mediated through functional effects on the calcium metabolic system. Little explored in pregnancy, we aimed to examine the relative importance of serum 25-hydroxyvitamin D (25(OH)D) and calcium intake on parathyroid hormone (PTH) concentrations in healthy white-skinned pregnant women. This cross-sectional analysis included 142 participants (14 ± 2 weeks’ gestation) at baseline of a vitamin D intervention trial at 51.9 °N. Serum 25(OH)D, PTH, and albumin-corrected calcium were quantified biochemically. Total vitamin D and calcium intakes (diet and supplements) were estimated using a validated food frequency questionnaire. The mean ± SD vitamin D intake was 10.7 ± 5.2 μg/day. With a mean ± SD serum 25(OH)D of 54.9 ± 22.6 nmol/L, 44% of women were <50 nmol/L and 13% <30 nmol/L. Calcium intakes (mean ± SD) were 1182 ± 488 mg/day and 23% of participants consumed <800 mg/day. The mean ± SD serum albumin-adjusted calcium was 2.2 ± 0.1 mmol/L and geometric mean (95% CI) PTH was 9.2 (8.4, 10.2) pg/mL. PTH was inversely correlated with serum 25(OH)D (r = −0.311, p < 0.001), but not with calcium intake or serum calcium (r = −0.087 and 0.057, respectively, both p > 0.05). Analysis of variance showed that while serum 25(OH)D (dichotomised at 50 nmol/L) had a significant effect on PTH (p = 0.025), calcium intake (<800, 800–1000, ≥1000 mg/day) had no effect (p = 0.822). There was no 25(OH)D-calcium intake interaction effect on PTH (p = 0.941). In this group of white-skinned women with largely sufficient calcium intakes, serum 25(OH)D was important for maintaining normal PTH concentration.

The impact of dietary calcium intake and vitamin D status on the effects of zoledronate

2012 ◽  
Vol 24 (1) ◽  
pp. 349-354 ◽  
Author(s):  
S. Bourke ◽  
M. J. Bolland ◽  
A. Grey ◽  
A. M. Horne ◽  
D. J. Wattie ◽  
...  
Keyword(s):  
Vitamin D ◽  
Calcium Intake ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Vitamin D Status ◽  
The Impact

Association of vitamin D receptor polymorphism with calcaneal broadband ultrasound attenuation in Korean postmenopausal women with low calcium intake

2007 ◽  
Vol 98 (5) ◽  
pp. 878-881 ◽  
Author(s):  
Hee-Seon Kim ◽  
Ji-Sun Kim ◽  
Nam Soo Kim ◽  
Jin Ho Kim ◽  
Byung-Kook Lee
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Calcium Intake ◽  
Broadband Ultrasound Attenuation ◽  
Multiple Regression Model ◽  
Community Dwelling ◽  
Dietary Reference Intake ◽  
Dietary Intakes ◽  
Ultrasound Attenuation ◽  
Low Calcium

This study investigated the associations among vitamin D receptor (VDR)BsmI polymorphism, calcium intake and bone strength as indicated by the broadband ultrasound attenuation (BUA) measured by calcaneal quantitative ultrasound at the left calcaneus in community-dwelling subjects with a low calcium intake. The VDRBsmI polymorphism was analysed in 335 women older than 65 years residing in rural Asan, Korea. Calcium intake was assessed with a 2 d, 24 h recall method. The distribution of genotypes was similar to that reported in other Asian populations (92 % bb, 7 % Bb and 1 % BB). The calcaneal BUA was significantly higher (P = 0·013) in the bb genotype than in the Bb or BB genotype (Bb and BB genotypes were combined due to the small number of BB subjects) in a multiple regression model after adjusting for age, body weight, height, physical activity and nutritional factors. BUA was not significantly affected by the calcium intake regardless of the genotype, cross-sectionally. The energy-adjusted average calcium intake of this population was 439·6 mg/d (432·5 mg/d for bb and 522·3 mg/d for Bb or BB), and 96 % of the subjects had dietary intakes that were less than the recommended Dietary Reference Intake for Koreans (which for calcium is 800 mg/d for women older than 65 years). In summary, the BUA in older Korean women with a low calcium intake was significantly influenced by the VDR genotype but not by the calcium intake, cross-sectionally.

scholarly journals Maternal vitamin D status and calcium intake interact to affect fetal skeletal growth in utero in pregnant adolescents

2012 ◽  
Vol 95 (5) ◽  
pp. 1103-1112 ◽  
Author(s):  
Bridget E Young ◽  
Thomas J McNanley ◽  
Elizabeth M Cooper ◽  
Allison W McIntyre ◽  
Frank Witter ◽  
...  
Keyword(s):  
Vitamin D ◽  
Calcium Intake ◽  
In Utero ◽  
Skeletal Growth ◽  
Vitamin D Status ◽  
Pregnant Adolescents ◽  
Maternal Vitamin ◽  
Maternal Vitamin D Status
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