Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors

Lina Juknaitė; Raminta Venskutonytė; Zeinab Assaf; Sophie Faure; Thierry Gefflaut; David J. Aitken; Birgitte Nielsen; Michael Gajhede; Jette S. Kastrup; Lennart Bunch; Karla Frydenvang; Darryl S. Pickering

doi:10.1016/j.jsb.2012.07.001

Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors

Journal of Structural Biology ◽

10.1016/j.jsb.2012.07.001 ◽

2012 ◽

Vol 180 (1) ◽

pp. 39-46 ◽

Cited By ~ 10

Author(s):

Lina Juknaitė ◽

Raminta Venskutonytė ◽

Zeinab Assaf ◽

Sophie Faure ◽

Thierry Gefflaut ◽

...

Keyword(s):

Glutamate Receptors ◽

Structural Characterization ◽

Ionotropic Glutamate Receptors ◽

Conformationally Restricted ◽

Glutamate Analogues

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Pharmacological characterization of (4R)-alkyl glutamate analogues at the ionotropic glutamate receptors — Focus on subtypes iGlu5–7

European Journal of Pharmacology ◽

10.1016/j.ejphar.2009.03.011 ◽

2009 ◽

Vol 609 (1-3) ◽

pp. 1-4 ◽

Cited By ~ 9

Author(s):

Lennart Bunch ◽

Thierry Gefflaut ◽

Sebastien Alaux ◽

Emanuelle Sagot ◽

Birgitte Nielsen ◽

...

Keyword(s):

Glutamate Receptors ◽

Ionotropic Glutamate Receptors ◽

Pharmacological Characterization ◽

Glutamate Analogues

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Illuminating Ionotropic Glutamate Receptors: Characterization of Fluorescent Antagonists Based on Polyamine Toxins

Biophysical Journal ◽

10.1016/j.bpj.2012.11.1524 ◽

2013 ◽

Vol 104 (2) ◽

pp. 272a

Author(s):

Christel B. Jensen ◽

Niels G. Nørager ◽

Anders S. Kristensen ◽

Kristian Strømgaard

Keyword(s):

Glutamate Receptors ◽

Ionotropic Glutamate Receptors ◽

Polyamine Toxins

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Functional Characterization of Tet-AMPA [Tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic Acid] Analogues at Ionotropic Glutamate Receptors GluR1−GluR4. The Molecular Basis for the Functional Selectivity Profile of 2-Bn-Tet-AMPA

Journal of Medicinal Chemistry ◽

10.1021/jm070532r ◽

2007 ◽

Vol 50 (17) ◽

pp. 4177-4185 ◽

Cited By ~ 10

Author(s):

Anders A. Jensen ◽

Thomas Christesen ◽

Ulrik Bølcho ◽

Jeremy R. Greenwood ◽

Giovanna Postorino ◽

...

Keyword(s):

Glutamate Receptors ◽

Propionic Acid ◽

Molecular Basis ◽

Functional Characterization ◽

Ionotropic Glutamate Receptors ◽

Functional Selectivity

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Molecular and immunochemical characterization of the ionotropic glutamate receptors in the rat heart

Brain Research Bulletin ◽

10.1016/s0361-9230(98)00012-4 ◽

1998 ◽

Vol 46 (5) ◽

pp. 429-434 ◽

Cited By ~ 64

Author(s):

Santokh S. Gill ◽

Olga M. Pulido ◽

Reudi W. Mueller ◽

Peter F. McGuire

Keyword(s):

Glutamate Receptors ◽

Rat Heart ◽

Ionotropic Glutamate Receptors ◽

Immunochemical Characterization

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Characterization of ionotropic glutamate receptors in insect neuro-muscular junction

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology ◽

10.1016/j.cbpc.2008.07.010 ◽

2009 ◽

Vol 149 (3) ◽

pp. 275-280 ◽

Cited By ~ 6

Author(s):

I.M. Fedorova ◽

L.G. Magazanik ◽

D.B. Tikhonov

Keyword(s):

Glutamate Receptors ◽

Ionotropic Glutamate Receptors

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4,4-Dimethyl- and Diastereomeric 4-Hydroxy-4-methyl- (2S)-Glutamate Analogues Display Distinct Pharmacological Profiles at Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters

ChemMedChem ◽

10.1002/cmdc.200900258 ◽

2009 ◽

Vol 4 (11) ◽

pp. 1925-1929 ◽

Cited By ~ 3

Author(s):

Lennart Bunch ◽

Darryl S. Pickering ◽

Thierry Gefflaut ◽

Virginie Vinatier ◽

Virgil Helaine ◽

...

Keyword(s):

Amino Acid ◽

Glutamate Receptors ◽

Excitatory Amino Acid ◽

Ionotropic Glutamate Receptors ◽

Amino Acid Transporters ◽

Excitatory Amino Acid Transporters ◽

Glutamate Analogues ◽

Pharmacological Profiles

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Pharmacological characterization of ionotropic glutamate receptors in the zebrafish olfactory bulb

Neuroscience ◽

10.1016/s0306-4522(03)00544-x ◽

2003 ◽

Vol 122 (4) ◽

pp. 1037-1047 ◽

Cited By ~ 24

Author(s):

J.G Edwards ◽

W.C Michel

Keyword(s):

Olfactory Bulb ◽

Glutamate Receptors ◽

Ionotropic Glutamate Receptors ◽

Pharmacological Characterization

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Correction to Chemoenzymatic Synthesis of New 2,4-syn-Functionalized (S)-Glutamate Analogues and Structure–Activity Relationship Studies at Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters

Journal of Medicinal Chemistry ◽

10.1021/jm400829s ◽

2013 ◽

Vol 56 (14) ◽

pp. 5985-5985 ◽

Cited By ~ 1

Author(s):

Zeinab Assaf ◽

Anja P. Larsen ◽

Raminta Venskutonytė ◽

Liwei Han ◽

Bjarke Abrahamsen ◽

...

Keyword(s):

Amino Acid ◽

Glutamate Receptors ◽

Excitatory Amino Acid ◽

Structure Activity Relationship ◽

Chemoenzymatic Synthesis ◽

Ionotropic Glutamate Receptors ◽

Activity Relationship ◽

Amino Acid Transporters ◽

Structure Activity ◽

Glutamate Analogues

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Chemoenzymatic Synthesis of New 2,4-syn-Functionalized (S)-Glutamate Analogues and Structure–Activity Relationship Studies at Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters

Journal of Medicinal Chemistry ◽

10.1021/jm301433m ◽

2013 ◽

Vol 56 (4) ◽

pp. 1614-1628 ◽

Cited By ~ 30

Author(s):

Zeinab Assaf ◽

Anja P. Larsen ◽

Raminta Venskutonytė ◽

Liwei Han ◽

Bjarke Abrahamsen ◽

...

Keyword(s):

Amino Acid ◽

Glutamate Receptors ◽

Excitatory Amino Acid ◽

Structure Activity Relationship ◽

Chemoenzymatic Synthesis ◽

Ionotropic Glutamate Receptors ◽

Activity Relationship ◽

Amino Acid Transporters ◽

Structure Activity ◽

Glutamate Analogues

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Structural characterization of intracellular C-terminal domains of group III metabotropic glutamate receptors

FEBS Letters ◽

10.1016/j.febslet.2010.12.042 ◽

2011 ◽

Vol 585 (3) ◽

pp. 511-516 ◽

Cited By ~ 7

Author(s):

Angela Seebahn ◽

Holger Dinkel ◽

Jeannine Mohrlüder ◽

Rudolf Hartmann ◽

Nico Vogel ◽

...

Keyword(s):

Glutamate Receptors ◽

Structural Characterization ◽

Metabotropic Glutamate Receptors ◽

Group Iii ◽

Metabotropic Glutamate ◽

Terminal Domains

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