Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium

2012 ◽  
Vol 180 (2) ◽  
pp. 327-334 ◽  
Author(s):  
Xiaoting Qiu ◽  
Yuyong Tao ◽  
Yuwei Zhu ◽  
Ye Yuan ◽  
Yujie Zhang ◽  
...  
Keyword(s):  
Enzymatic Activity ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Structural Insights

scholarly journals Massiliamide, a cyclic tetrapeptide with potent tyrosinase inhibitory properties from the Gram-negative bacterium Massilia albidiflava DSM 17472T

2020 ◽  
Author(s):  
Andri Frediansyah ◽  
Jan Straetener ◽  
Heike Brötz-Oesterhelt ◽  
Harald Gross
Keyword(s):  
Absolute Configuration ◽  
Inhibitory Activity ◽  
Liquid Culture ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Negative Bacterium ◽  
Gram Negative ◽  
The Absolute ◽  
Potent Inhibitory Activity ◽  
Cyclic Tetrapeptide

AbstractA cyclic tetrapeptide, designated massiliamide, was isolated from the liquid culture of the Gram-negative bacterium Massilia albidiflava DSM 17472T. The structure was elucidated through extensive spectroscopic analysis, including HR-MS and 1D and 2D NMR experiments. The absolute configuration was determined using the Marfey´s method. Massiliamide showed potent inhibitory activity towards tyrosinase with an IC50 value of 1.15 µM and no cytotoxicity.

scholarly journals Porphyromonas gingivalis fimbrial protein Mfa5 contains a von Willebrand factor domain and an intramolecular isopeptide

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Thomas V. Heidler ◽  
Karin Ernits ◽  
Agnieszka Ziolkowska ◽  
Rolf Claesson ◽  
Karina Persson
Keyword(s):  
Porphyromonas Gingivalis ◽  
Von Willebrand Factor ◽  
Host Cells ◽  
Negative Bacterium ◽  
Oral Biofilm ◽  
Gram Negative ◽  
Type V ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Fimbrial Protein

AbstractThe Gram-negative bacterium Porphyromonas gingivalis is a secondary colonizer of the oral biofilm and is involved in the onset and progression of periodontitis. Its fimbriae, of type-V, are important for attachment to other microorganisms in the biofilm and for adhesion to host cells. The fimbriae are assembled from five proteins encoded by the mfa1 operon, of which Mfa5 is one of the ancillary tip proteins. Here we report the X-ray structure of the N-terminal half of Mfa5, which reveals a von Willebrand factor domain and two IgG-like domains. One of the IgG-like domains is stabilized by an intramolecular isopeptide bond, which is the first such bond observed in a Gram-negative bacterium. These features make Mfa5 structurally more related to streptococcal adhesins than to the other P. gingivalis Mfa proteins. The structure reported here indicates that horizontal gene transfer has occurred among the bacteria within the oral biofilm.

scholarly journals Anion inhibition studies of the Zn(II)-bound ι-carbonic anhydrase from the Gram-negative bacterium Burkholderia territorii

2021 ◽  
Vol 36 (1) ◽  
pp. 372-376
Author(s):  
Andrea Petreni ◽  
Viviana De Luca ◽  
Andrea Scaloni ◽  
Alessio Nocentini ◽  
Clemente Capasso ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Inhibition Studies

The structure of the O-polysaccharide isolated from pectinolytic gram-negative bacterium Dickeya aquatica IFB0154 is different from the O-polysaccharides of other Dickeya species

2020 ◽  
Vol 497 ◽  
pp. 108135
Author(s):  
Agnieszka Kowalczyk ◽  
Nikola Szpakowska ◽  
Wojciech Sledz ◽  
Agata Motyka-Pomagruk ◽  
Karolina Ossowska ◽  
...  
Keyword(s):  
Negative Bacterium ◽  
Gram Negative

scholarly journals Draft Genome Sequence of Pantoea sp. Strain A4, a Rafflesia-Associated Bacterium That ProducesN-Acylhomoserine Lactones as Quorum-Sensing Molecules

2012 ◽  
Vol 194 (23) ◽  
pp. 6610-6610 ◽  
Author(s):  
Kar-Wai Hong ◽  
Han Ming Gan ◽  
Siew-Moon Low ◽  
Patrick Kok Yuen Lee ◽  
Yee-Meng Chong ◽  
...  
Keyword(s):  
Quorum Sensing ◽  
Genome Sequence ◽  
Draft Genome ◽  
Draft Genome Sequence ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Content Type ◽  
First Time

ABSTRACTPantoeasp. strain A4 is a Gram-negative bacterium isolated from theRafflesiaflower. We present here, for the first time, the genome sequence ofRafflesia-associatedPantoeasp. strain A4, which exhibited quorum-sensing activity.

Efficacy of crude extracts of Clitoria ternatea for antibacterial activity against gram negative bacterium (Proteus mirabilis)

2019 ◽  
Vol 21 ◽  
pp. 101328 ◽  
Author(s):  
S. Dhanasekaran ◽  
A. Rajesh ◽  
Thangavel Mathimani ◽  
S. Melvin Samuel ◽  
Rajasree Shanmuganathan ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Proteus Mirabilis ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Clitoria Ternatea ◽  
Crude Extracts

scholarly journals Helicobacter pylori colonization and oral health in children

2017 ◽  
Vol 12 (2) ◽  
pp. 41-44
Author(s):  
Vasile Valeriu LUPU ◽  
◽  
Gabriela PĂDURARU ◽  
Anca ADAM ◽  
Ana-Maria DĂBULEANU ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Oral Health ◽  
Gastric Mucosa ◽  
Oral Cavity ◽  
Gold Standard ◽  
Dental Plaque ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Standard Triple Therapy ◽  
H Pylori

Helicobacter pylori (H. pylori) is a microaerophilic gram-negative bacterium infecting approximately one half of the world’s population. The oral cavity and dental plaque may be a reservoir for H. pylori infection. Diagnosis of H. pylori infection in children differs from that of adults. Although H. pylori has long been known to be detected in the oral cavity, the significance of such findings are controversial. Oral H. pylori may play an important role in re-infection of the gastric mucosa. The gold standard for eradicating H. pylori infection is standard triple therapy. The studies have shown promising results in the management of both oral and gastric H. pylori.

Sign in / Sign up

Export Citation Format

Share Document