scholarly journals High-throughput characterization of intrinsic disorder in proteins from the Protein Structure Initiative

2012 ◽  
Vol 180 (1) ◽  
pp. 201-215 ◽  
Author(s):  
Derrick E. Johnson ◽  
Bin Xue ◽  
Megan D. Sickmeier ◽  
Jingwei Meng ◽  
Marc S. Cortese ◽  
...  
Keyword(s):  
Protein Structure ◽  
High Throughput ◽  
Intrinsic Disorder ◽  
Protein Structure Initiative

scholarly journals High-throughput Characterization of Intrinsically Disordered Proteins from the Protein Structure Initiative

2009 ◽  
Vol 96 (3) ◽  
pp. 220a
Author(s):  
Derrick E. Johnson ◽  
Megan D. Sickmeier ◽  
Jingwei Meng ◽  
Tanguy Le Gall ◽  
Vladimir Uversky ◽  
...  
Keyword(s):  
Protein Structure ◽  
High Throughput ◽  
Intrinsically Disordered Proteins ◽  
Disordered Proteins ◽  
Protein Structure Initiative ◽  
Intrinsically Disordered

Combinatorial Fabrication and High-Throughput Characterization of Thin Film Metal Oxide Libraries for Solar water Splitting

2018 ◽  
Author(s):  
Alfred Ludwig ◽  
Mona Nowak ◽  
Swati Kumari ◽  
Helge S. Stein ◽  
Ramona Gutkowski ◽  
...  
Keyword(s):  
Thin Film ◽  
Metal Oxide ◽  
Water Splitting ◽  
High Throughput ◽  
Solar Water ◽  
Solar Water Splitting

scholarly journals Physicochemical Characterization Cascade of Nanoadjuvant–Antigen Systems for Improving Vaccines

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 544
Author(s):  
Giuditta Guerrini ◽  
Antonio Vivi ◽  
Sabrina Gioria ◽  
Jessica Ponti ◽  
Davide Magrì ◽  
...  
Keyword(s):  
Immune Response ◽  
Protein Structure ◽  
Physicochemical Properties ◽  
Physicochemical Characterization ◽  
Protein Antigen ◽  
Efficacy And Safety

Adjuvants have been used for decades to enhance the immune response to vaccines, in particular for the subunit-based adjuvants. Physicochemical properties of the adjuvant-protein antigen complexes, such as size, morphology, protein structure and binding, influence the overall efficacy and safety of the vaccine. Here we show how to perform an accurate physicochemical characterization of the nanoaluminum–ovalbumin complex. Using a combination of existing techniques, we developed a multi-staged characterization strategy based on measurements of increased complexity. This characterization cascade has the advantage of being very flexible and easily adaptable to any adjuvant-protein antigen combinations. It will contribute to control the quality of antigen–adjuvant complexes and immunological outcomes, ultimately leading to improved vaccines.

scholarly journals Database of ab initio L-edge X-ray absorption near edge structure

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Yiming Chen ◽  
Chi Chen ◽  
Chen Zheng ◽  
Shyam Dwaraknath ◽  
Matthew K. Horton ◽  
...  
Keyword(s):  
High Throughput ◽  
Scattering Theory ◽  
Research Community ◽  
Metal Compounds ◽  
Edge Structure ◽  
X Ray ◽  
Initial Release ◽  
Computational Workflow ◽  
X Ray Absorption

AbstractThe L-edge X-ray Absorption Near Edge Structure (XANES) is widely used in the characterization of transition metal compounds. Here, we report the development of a database of computed L-edge XANES using the multiple scattering theory-based FEFF9 code. The initial release of the database contains more than 140,000 L-edge spectra for more than 22,000 structures generated using a high-throughput computational workflow. The data is disseminated through the Materials Project and addresses a critical need for L-edge XANES spectra among the research community.

High-Throughput Synthesis and Characterization of a Combinatorial Materials Library in Bulk Alloys

2021 ◽  
Vol 52 (4) ◽  
pp. 1159-1168
Author(s):  
Lei Zhao ◽  
Yuanxun Zhou ◽  
Hui Wang ◽  
Xuebin Chen ◽  
Lixia Yang ◽  
...  
Keyword(s):  
High Throughput ◽  
Synthesis And Characterization ◽  
Combinatorial Materials ◽  
Bulk Alloys

High-Throughput Screening and Characterization of a High-Density Soybean Mutant Library Elucidate the Biosynthesis Pathway of Triterpenoid Saponins

2019 ◽  
Vol 60 (5) ◽  
pp. 1082-1097 ◽  
Author(s):  
Panneerselvam Krishnamurthy ◽  
Yukiko Fujisawa ◽  
Yuya Takahashi ◽  
Hanako Abe ◽  
Kentaro Yamane ◽  
...  
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
High Density ◽  
Biosynthesis Pathway ◽  
Mutant Library ◽  
Triterpenoid Saponins

High-Throughput Characterization of Small and Large Molecules Using Only a Matrix and the Vacuum of a Mass Spectrometer

2015 ◽  
Vol 87 (9) ◽  
pp. 4667-4674 ◽  
Author(s):  
Daniel W. Woodall ◽  
Beixi Wang ◽  
Ellen D. Inutan ◽  
Srinivas B. Narayan ◽  
Sarah Trimpin
Keyword(s):  
Mass Spectrometer ◽  
High Throughput ◽  
Large Molecules
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