scholarly journals Barriers and facilitators of hepatitis C treatment uptake among people who inject drugs enrolled in opioid treatment programs in Baltimore

2019 ◽  
Vol 100 ◽  
pp. 45-51 ◽  
Author(s):  
Oluwaseun Falade-Nwulia ◽  
Risha Irvin ◽  
Alana Merkow ◽  
Mark Sulkowski ◽  
Alexander Niculescu ◽  
...  
Keyword(s):  
Hepatitis C ◽  
People Who Inject Drugs ◽  
Barriers And Facilitators ◽  
Treatment Programs ◽  
Hepatitis C Treatment ◽  
Opioid Treatment ◽  
Treatment Uptake

scholarly journals Hepatitis C treatment uptake among people who inject drugs in the oral direct‐acting antiviral era

2020 ◽  
Vol 40 (10) ◽  
pp. 2407-2416
Author(s):  
Oluwaseun Falade‐Nwulia ◽  
Rachel E. Gicquelais ◽  
Jacquie Astemborski ◽  
Sean D. McCormick ◽  
Greg Kirk ◽  
...  
Keyword(s):  
Hepatitis C ◽  
People Who Inject Drugs ◽  
Hepatitis C Treatment ◽  
Direct Acting Antiviral ◽  
Treatment Uptake ◽  
Direct Acting

Defining populations and injecting parameters among people who inject drugs: Implications for the assessment of hepatitis C treatment programs

2015 ◽  
Vol 26 (10) ◽  
pp. 950-957 ◽  
Author(s):  
Sarah Larney ◽  
Jason Grebely ◽  
Matthew Hickman ◽  
Daniela De Angelis ◽  
Gregory J. Dore ◽  
...  
Keyword(s):  
Hepatitis C ◽  
People Who Inject Drugs ◽  
Treatment Programs ◽  
Hepatitis C Treatment

THU-118-Factors associated with hepatitis C treatment uptake among people who inject drugs in a population based data linkage study

2019 ◽  
Vol 70 (1) ◽  
pp. e210-e211
Author(s):  
Sofia Bartlett ◽  
Stanley Wong ◽  
Amanda Yu ◽  
Maria Alvarez ◽  
Terri Buller-Taylor ◽  
...  
Keyword(s):  
Hepatitis C ◽  
People Who Inject Drugs ◽  
Data Linkage ◽  
Population Based ◽  
Linkage Study ◽  
Hepatitis C Treatment ◽  
Factors Associated ◽  
Treatment Uptake

Barriers and Facilitators of HIV and Hepatitis C Care Among People Who Inject Drugs in Nairobi, Kenya: A Qualitative Study with Peer Educators

2021 ◽  
Author(s):  
Natasha Ludwig-Barron ◽  
Brandon L Guthrie ◽  
Loice Mbogo ◽  
David Bukusi ◽  
William Sinkele ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Law Enforcement ◽  
Harm Reduction ◽  
People Who Inject Drugs ◽  
Community Level ◽  
Barriers And Facilitators ◽  
Peer Educators ◽  
Prevention Education ◽  
Individual Level ◽  
Policy Level

Abstract Background: In Kenya, people who inject drugs (PWID) are disproportionately affected by HIV and hepatitis C (HCV) epidemics, including HIV-HCV coinfections; however, few have assessed factors affecting their access to and engagement in care through the lens of harm reduction specialists. This qualitative study leverages the personal and professional experiences of peer educators to help identify HIV and HCV barriers and facilitators to care among PWID in Nairobi, including resource recommendations to improve service uptake. Methods: We recruited peer educators from two harm reduction facilities in Nairobi, Kenya, using random and purposive sampling techniques. Semi-structured interviews explored circumstances surrounding HIV and HCV service access, prevention education and resource recommendations. A thematic analysis was conducted using the Modified Social Ecological Model (MSEM) as an underlying framework, with illustrative quotes highlighting emergent themes. Results: Twenty peer educators participated, including six women, with 2 months to 6 years of harm reduction service. Barriers to HIV and HCV care were organized by (a) individual-level themes including competing needs of addiction and misinterpreted symptoms; (b) network-level themes including social isolation and drug pusher interactions; (c) community-level themes including transportation, mental and rural healthcare services, and limited HCV resources; and (d) policy-level themes including nonintegrated services, clinical administration, and law enforcement. Stigma, an overarching barrier, was highlighted throughout the MSEM. Facilitators to HIV and HCV care were comprised of (a) individual-level themes including concurrent care, personal reflections, and religious beliefs; (b) network-level themes including community recommendations, navigation services, family commitment, and employer support; (c) community-level themes including quality services, peer support, and outreach; and (d) policy-level themes including integrated services and medicalized approaches within law enforcement. Participant resource recommendations include (i) additional medical, social and ancillary support services, (ii) national strategies to address stigma and violence and (iii) HCV prevention education. Conclusions : Peer educators provided intimate knowledge of PWID barriers and facilitators to HIV and HCV care that were described at each level of the MSEM, and should be given careful consideration when developing future initiatives. Recommendations emphasized policy and community-level interventions including educational campaigns and program suggestions to supplement existing HIV and HCV services.

Peer to peer communication about hepatitis C treatment amongst people who inject drugs: A longitudinal qualitative study

2021 ◽  
Vol 87 ◽  
pp. 102983
Author(s):  
Stelliana Goutzamanis ◽  
Joseph S Doyle ◽  
Danielle Horyniak ◽  
Peter Higgs ◽  
Margaret Hellard
Keyword(s):  
Hepatitis C ◽  
Qualitative Study ◽  
People Who Inject Drugs ◽  
Peer To Peer ◽  
Peer Communication ◽  
Hepatitis C Treatment

Reasons for Not Seeking Hepatitis C Treatment among People Who Inject Drugs

2020 ◽  
pp. 1-10
Author(s):  
Leith Morris ◽  
Linda Selvey ◽  
Owain Williams ◽  
Charles Gilks ◽  
Andrew Smirnov
Keyword(s):  
Hepatitis C ◽  
People Who Inject Drugs ◽  
Hepatitis C Treatment

Outcomes of Treatment for Hepatitis C in Primary Care, Compared to Hospital-based Care: A Randomized, Controlled Trial in People Who Inject Drugs

2019 ◽  
Vol 70 (9) ◽  
pp. 1900-1906 ◽  
Author(s):  
Amanda J Wade ◽  
Joseph S Doyle ◽  
Edward Gane ◽  
Catherine Stedman ◽  
Bridget Draper ◽  
...  
Keyword(s):  
Primary Care ◽  
Hepatitis C ◽  
People Who Inject Drugs ◽  
Controlled Trial ◽  
Standard Of Care ◽  
Virologic Response ◽  
World Health ◽  
Specialist Care ◽  
Treatment Uptake ◽  
Historical Controls

Abstract Background To achieve the World Health Organization hepatitis C virus (HCV) elimination targets, it is essential to increase access to direct-acting antivirals (DAAs), especially among people who inject drugs (PWID). We aimed to determine the effectiveness of providing DAAs in primary care, compared with hospital-based specialist care. Methods We randomized PWID with HCV attending primary care sites in Australia or New Zealand to receive DAAs at their primary care site or local hospital (standard of care [SOC]). The primary outcome was to determine whether people treated in primary care had a noninferior rate of sustained virologic response at Week 12 (SVR12), compared to historical controls (consistent with DAA trials at the time of the study design); secondary outcomes included comparisons of treatment initiation, SVR12 rates, and the care cascade by study arm. Results We recruited 140 participants and randomized 136: 70 to the primary care arm and 66 to the SOC arm. The SVR12 rate (100%, 95% confidence interval [CI] 87.7–100) of people treated in primary care was noninferior when compared to historical controls (85% assumed). An intention-to-treat analysis revealed that the proportion of participants commencing treatment in the primary care arm (75%, 43/57) was significantly higher than in the SOC arm (34%, 18/53; P < .001; relative risk [RR] 2.48, 95% CI 1.54–3.95), and the proportion of participants with SVR12 was significantly higher in the primary care arm, compared to in the SOC arm (49% [28/57] and 30% [16/53], respectively; P = .043; RR 1.63, 95% CI 1.0–2.65). Conclusions Providing HCV treatment in primary care increases treatment uptake and cure rates. Approaches that increase treatment uptake among PWID will accelerate elimination strategies. Clinical Trials Registration NCT02555475.

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