Is the metrial gland really a gland?

2004 ◽  
Vol 61 (2) ◽  
pp. 129-131 ◽  
Author(s):  
Rupasri Ain ◽  
Michael J. Soares
Keyword(s):  
Metrial Gland

THE FALL OF BLOOD PRESSURE FOLLOWING INDUCTION OF DECIDUOMATA IN STEROID HYPERTENSIVE RATS RECEIVING PROGESTERONE

1968 ◽  
Vol 59 (2) ◽  
pp. 227-234 ◽  
Author(s):  
H. C. Moore ◽  
I. Cserhati ◽  
F. P. Biliczki
Keyword(s):  
Blood Pressure ◽  
Hypotensive Effect ◽  
Hypertensive Rats ◽  
Pregnant Rats ◽  
Hypertensive Rat ◽  
Equivalent Time ◽  
Metrial Gland ◽  
Blood Pressure Responses ◽  
A Minor ◽  
Maternal Decidua

ABSTRACT Experimental deciduomata and progesterone together lower the blood pressure in the steroid hypertensive rat from the 5th to 10th day of decidual growth i. e. from the 10th to 15th day of pseudopregnancy. This would suggest that the fall of blood pressure at an equivalent time of gestation in hypertensive pregnant rats could be due to the maternal decidua under the influence of progesterone. It is further considered that the metrial gland of the deciduoma is more likely to be responsible for the hypotensive effect and by comparison that the metrial gland is implicated in the hypotensive effect of pregnancy. Progesterone alone also exerts a minor hypotensive effect in those animals in which a nephrectomy forms part of the hypertension regimen and indicates one way in which a maternal renal factor could influence blood pressure responses in hypertensive pregnant rats.

scholarly journals Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization

1988 ◽  
Vol 106 (2) ◽  
pp. 441-450 ◽  
Author(s):  
S Nomura ◽  
AJ Wills ◽  
DR Edwards ◽  
JK Heath ◽  
BL Hogan
Keyword(s):  
In Situ Hybridization ◽  
Bone Development ◽  
Mouse Cell ◽  
Sensory Epithelium ◽  
Developmental Expression ◽  
Granulated Metrial Gland Cells ◽  
Metrial Gland ◽  
Temporal And Spatial

2ar has been identified as a gene inducible by tumor promoters and growth factors in a variety of cultured mouse cell lines (Smith, J. H., and D. T. Denhardt. 1987. J. Cell. Biochem. 34:13-22). Sequence analysis shows that it codes for mouse osteopontin, an RGDS-containing, phosphorylated, sialic acid-rich Ca++-binding protein originally isolated from bone (Oldberg, A., A. Franzen, and D. Heinegard. 1986. Proc. Natl. Acad. Sci. USA. 83:8819-8823; Prince, C. W., T. Oosawa, W. T. Butler, M. Tomana, A. S. Brown, and R. E. Schrohenloer. 1987. J. Biol. Chem. 262:2900-3907.). In this paper we use Northern blot analysis and in situ hybridization to localize expression of 2ar during mouse embryogenesis. 2ar RNA is first detected in developing limb bones and calvaria at 14.5 d p.c., in a population of cells distinct from those expressing SPARC (osteonectin). High levels of 2ar expression are also seen in the bone marrow-derived granulated metrial gland cells of the deciduum and placenta, and in a number of epithelial tissues, including embryonic and postnatal kidney tubules, uterine epithelium and sensory epithelium of the embryonic ear. The temporal and spatial pattern of 2ar expression seen in vivo suggests that the protein plays a wider role than previously realized, in processes which are not confined to bone development.

Characterization of cytokine production by the metrial gland and granulated metrial gland cells

1991 ◽  
Vol 19 (2) ◽  
pp. 149-166 ◽  
Author(s):  
B. Anne Croy ◽  
Larry J. Guilbert ◽  
Melissa A. Browne ◽  
Nicholas M. Gough ◽  
Dan T. Stinchcomb ◽  
...  
Keyword(s):  
Cytokine Production ◽  
Gland Cells ◽  
Granulated Metrial Gland Cells ◽  
Metrial Gland
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