RNASET2 — An autoantigen in anaplastic large cell lymphoma identified by protein array analysis

2012 ◽  
Vol 75 (17) ◽  
pp. 5279-5292 ◽  
Author(s):  
Suketu Patel ◽  
Hong Chen ◽  
Laura Monti ◽  
Edith Gould ◽  
Eugenia Haralambieva ◽  
...  
Keyword(s):  
Anaplastic Large Cell Lymphoma ◽  
Cell Lymphoma ◽  
Large Cell ◽  
Protein Array ◽  
Array Analysis ◽  
Large Cell Lymphoma ◽  
Protein Array Analysis

Current Approaches to Diagnosis and Treatment of Anaplastic Large Cell Lymphoma in Children

2015 ◽  
Vol 2 (3) ◽  
pp. 205-211
Author(s):  
A.S. Fedorova ◽  
◽  
A.M. Kustanovich ◽  
O.V. Aleinikova ◽  
◽  
...  
Keyword(s):  
Anaplastic Large Cell Lymphoma ◽  
Cell Lymphoma ◽  
Large Cell ◽  
Diagnosis And Treatment ◽  
Large Cell Lymphoma

A Case of Secondary Cutaneous CD30+ Anaplastic Large Cell Lymphoma.

1993 ◽  
Vol 55 (4) ◽  
pp. 680-685
Author(s):  
Kazufumi GOTO ◽  
Shinichi ANZAI ◽  
Kazuo ASO ◽  
Hironobu SATO ◽  
Mikio MATSUDA ◽  
...  
Keyword(s):  
Anaplastic Large Cell Lymphoma ◽  
Cell Lymphoma ◽  
Large Cell ◽  
Large Cell Lymphoma

A Case of Primary Cutaneous Anaplastic Large Cell Lymphoma Occurring on the Upper Leg.

1998 ◽  
Vol 60 (2) ◽  
pp. 169-172
Author(s):  
Shih-hong LIN ◽  
Juichiro NAKAYAMA ◽  
Tetsuo MATSUDA ◽  
Akito TOSHITANI ◽  
Shinjiro MATSUO ◽  
...  
Keyword(s):  
Anaplastic Large Cell Lymphoma ◽  
Cell Lymphoma ◽  
Large Cell ◽  
Large Cell Lymphoma

scholarly journals Usefulness of BATF3 Immunohistochemistry in Diagnosing Classical Hodgkin Lymphoma

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1123
Author(s):  
Julian Benckendorff ◽  
Johanna Kuchar ◽  
Frank Leithäuser ◽  
Malena Zahn ◽  
Peter Möller
Keyword(s):  
Transcription Factor ◽  
Western Blot ◽  
Hodgkin Lymphoma ◽  
Anaplastic Large Cell Lymphoma ◽  
Diagnostic Marker ◽  
Cell Lymphoma ◽  
Large Cell ◽  
Classical Hodgkin Lymphoma ◽  
Highly Sensitive ◽  
Large Cell Lymphoma

It is well recognized that the AP-1 transcription factor BATF3 is constitutively expressed in Hodgkin/Reed-Sternberg (HRS) cells, but its potential as a diagnostic marker for classical Hodgkin lymphoma (cHL) has not yet been addressed. In this study, we performed immunohistochemistry and analyzed the BATF3 expression in lymphoma cells on 218 lymphoma samples belonging to 14 different lymphoma entities. We observed varying degrees of BATF3 expression in nearly half of the cases (n = 100) with BATF3 expression being a constitutive feature of cHL (n = 53) and anaplastic large cell lymphoma (ALCL). By scoring BATF3 expression (BATF3-score) we observed constitutively high BATF3-scores in cHL and ALCL and low to moderate BATF3-scores in all other entities examined. Western blot analysis confirmed BATF3 protein expression in cell lysates from cHL cell lines (n = 7). Thus, BATF3 can be considered a useful IHC marker for the diagnosis of cHL as it is highly sensitive and sufficiently specific when analyzed by BATF3-scoring.

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