Plasma protein changes in horse after prolonged physical exercise: A proteomic study

2012 ◽  
Vol 75 (14) ◽  
pp. 4494-4504 ◽  
Author(s):  
Fausto Scoppetta ◽  
Micaela Tartaglia ◽  
Giovanni Renzone ◽  
Luca Avellini ◽  
Alberto Gaiti ◽  
...  
1991 ◽  
Vol 71 (5) ◽  
pp. 1807-1812 ◽  
Author(s):  
I. Tabata ◽  
F. Ogita ◽  
M. Miyachi ◽  
H. Shibayama

The effects of low blood glucose concentration during low-intensity prolonged physical exercise on the hypothalamus-pituitary-adrenocortical axis were investigated in healthy young men. In experiment 1, six subjects who had fasted for 14 h performed bicycle exercise at 50% of their maximal O2 uptake until exhaustion. At the end of the exercise, adrenocorticotropic hormone (ACTH) and cortisol increased significantly. However, this hormonal response was totally abolished when the same subjects exercised at the same intensity while blood glucose concentrations were maintained at the preexercise level. In experiment 2, in addition to ACTH and cortisol, the possible changes in plasma concentration of corticotropin-releasing factor (CRF) were investigated during exercise of the same intensity performed by six subjects. As suggested by a previous study (Tabata et al. Clin. Physiol. Oxf. 4: 299–307, 1984), when the blood glucose concentrations decreased to less than 3.3 mM, plasma concentrations of CRF, ACTH, and cortisol showed a significant increase. At exhaustion, further increases were observed in plasma CRF, ACTH, and cortisol concentrations. These results demonstrate that decreases in blood glucose concentration trigger the pituitary-adrenocortical axis to enhance secretion of ACTH and cortisol during low-intensity prolonged exercise in humans. The data also might suggest that this activation is due to increased concentration of CRF, which was shown to increase when blood glucose concentration decreased to a critical level of 3.3 mM.


Enzyme ◽  
1985 ◽  
Vol 33 (3) ◽  
pp. 134-142 ◽  
Author(s):  
P. (a) Hespel ◽  
E. (b) Vanden Eynde ◽  
A. (a) Amery ◽  
P. (a) Lijnen

1995 ◽  
Vol 25 (1) ◽  
pp. 142-146 ◽  
Author(s):  
Alessandro Cosenzi ◽  
Ariela Sacerdote ◽  
Elena Bocin ◽  
Rossella Molino ◽  
Mariangela Mangiarotti ◽  
...  

1986 ◽  
Vol 18 (04) ◽  
pp. 278-279
Author(s):  
P. Satabin ◽  
D. Merino ◽  
B. Serrurier ◽  
C. Guezennec

1984 ◽  
Vol 52 (3) ◽  
pp. 300-304 ◽  
Author(s):  
C. Y. Guezennec ◽  
P. Ferre ◽  
B. Serrurier ◽  
D. Merino ◽  
M. Aymonod ◽  
...  

1993 ◽  
Vol 129 (2) ◽  
pp. 109-113 ◽  
Author(s):  
Tommi J Vasankari ◽  
Urho M Kujala ◽  
Olli J Heinonen ◽  
Ilpo T Huhtaniemi

The effect of several years' endurance training on hormonal changes during acute prolonged physical exercise was studied. In trial I, 13 cross-country skiers were studied before and after a 75-km ski race and 3 weeks later on a control day. In trial II, 10 trained and 8 untrained subjects bicycled for 4 h on the road with as high a performance level as possible. Venous blood samples were taken in both trials before and after the exercise. In trial I, serum concentrations of luteinizing hormone (p<0.01) and follicle-stimulating hormone (FSH, p <0.001) decreased more from morning to afternoon samples, and cortisol (p <0.001) and growth hormone (GH, p <0.001) increased more during the ski race when compared to the control day. Serum testosterone decreased during the ski race (p <0.01) but not on the control day. In trial II, a group difference was seen in serum FSH levels which was higher in the trained than untrained subjects at all three time points (F =4.66, p=0.046). A significant trial-group interaction (p =0.020) was seen in GH, the GH being lower before exercise and higher 2 h after exercise in the untrained subjects. There was a significant group contrast between pre- and post-exercise samples in testosterone (p = 0.021) and cortisol (p = 0.022). In conclusion, the higher basal FSH concentration in the trained versus untrained subjects may be a sign of compensated hypogonadism due to intensive chronic training or it may be due to dysfunction of Sertoli cells. Signs of adaptation to resist the hormonal changes caused by acute physical exercise can be seen in the trained subjects when compared to the untrained subjects.


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