Expression profiling of more than 3500 proteins of MSS-type colorectal cancer by stable isotope labeling and mass spectrometry

2012 ◽  
Vol 75 (10) ◽  
pp. 3050-3062 ◽  
Author(s):  
Un-Beom Kang ◽  
Jeonghun Yeom ◽  
Hye-Jung Kim ◽  
Hoguen Kim ◽  
Cheolju Lee
Keyword(s):  
Colorectal Cancer ◽  
Mass Spectrometry ◽  
Stable Isotope ◽  
Expression Profiling ◽  
Isotope Labeling ◽  
Stable Isotope Labeling

Methodology for the Validation of Isotopic Analyses by Mass Spectrometry in Stable-Isotope Labeling Experiments

2018 ◽  
Vol 90 (3) ◽  
pp. 1852-1860 ◽  
Author(s):  
Maud Heuillet ◽  
Floriant Bellvert ◽  
Edern Cahoreau ◽  
Fabien Letisse ◽  
Pierre Millard ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Stable Isotope ◽  
Isotope Labeling ◽  
Stable Isotope Labeling ◽  
Isotopic Analyses ◽  
Isotope Labeling Experiments

Determination of the Absolute Configuration of Peptide Natural Products by Using Stable Isotope Labeling and Mass Spectrometry

2012 ◽  
Vol 18 (8) ◽  
pp. 2342-2348 ◽  
Author(s):  
Helge B. Bode ◽  
Daniela Reimer ◽  
Sebastian W. Fuchs ◽  
Ferdinand Kirchner ◽  
Christina Dauth ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Natural Products ◽  
Stable Isotope ◽  
Absolute Configuration ◽  
Isotope Labeling ◽  
Stable Isotope Labeling ◽  
The Absolute

An Improved, Versatile, and Easily Scalable Synthesis of Sphingomyelins: Application to Stable Isotope Labeling

Synthesis ◽  
2020 ◽  
Vol 52 (14) ◽  
pp. 2106-2110
Author(s):  
Nicolas Philippe ◽  
Serge Pérard ◽  
Franck Le Strat ◽  
Jörg Blankenstein ◽  
Sébastien Roy
Keyword(s):  
Mass Spectrometry ◽  
Stable Isotope ◽  
Primary Amine ◽  
Isotope Labeling ◽  
Stable Isotope Labeling ◽  
Scalable Synthesis

With a view to make conveniently labeled mass spectrometry standards available, a set of deuterated sphingomyelins were prepared by a new expedient, flexible, robust, scalable, and high-yielding synthetic scheme starting from 2-azido-3-O-benzoylsphingosine as the key intermediate. Unlike previously published procedures, this work emphasizes the benefit arising from the choice of the azido function as a masking group for the reactive primary amine during the troublesome, though crucial, phosphorylation step.

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