Proteomic analysis of zebrafish (Danio rerio) embryos exposed to cyclosporine A

2012 ◽  
Vol 75 (3) ◽  
pp. 1004-1017 ◽  
Author(s):  
Ruby P. Ponnudurai ◽  
Trayambak Basak ◽  
Shadab Ahmad ◽  
Gourav Bhardwaj ◽  
Rajendra K. Chauhan ◽  
...  
Keyword(s):  
Cyclosporine A ◽  
Danio Rerio ◽  
Proteomic Analysis ◽  
Danio Rerio Embryos

Global proteomic analysis of lysine acetylation in zebrafish (Danio rerio) embryos

2016 ◽  
Vol 37 (23-24) ◽  
pp. 3137-3145 ◽  
Author(s):  
Oh Kwang Kwon ◽  
Sunjoo Kim ◽  
Sangkyu Lee
Keyword(s):  
Danio Rerio ◽  
Proteomic Analysis ◽  
Lysine Acetylation ◽  
Danio Rerio Embryos

Neurulation in the posterior region of zebrafish, Danio rerio embryos

2021 ◽  
Author(s):  
Julia Gladysheva ◽  
Evdokia Evnukova ◽  
Ekaterina Kondakova ◽  
Milana Kulakova ◽  
Vladimir Efremov
Keyword(s):  
Danio Rerio ◽  
Posterior Region ◽  
Danio Rerio Embryos

scholarly journals Gene co-expression network analysis reveals mechanisms underlying ozone-induced carbamazepine toxicity in zebrafish (Danio rerio) embryos

Chemosphere ◽  
2021 ◽  
Vol 276 ◽  
pp. 130282
Author(s):  
Johannes Pohl ◽  
Oksana Golovko ◽  
Gunnar Carlsson ◽  
Stefan Örn ◽  
Monika Schmitz ◽  
...  
Keyword(s):  
Network Analysis ◽  
Danio Rerio ◽  
Danio Rerio Embryos

91. Studies on impact of chilling on sox gene expression in zebrafish (Danio rerio) embryos

Cryobiology ◽  
2010 ◽  
Vol 61 (3) ◽  
pp. 389
Author(s):  
K.K. Desai ◽  
E. Spikings ◽  
D.M. Rawson ◽  
T. Zhang
Keyword(s):  
Gene Expression ◽  
Danio Rerio ◽  
Sox Gene ◽  
Danio Rerio Embryos

Short exposure to glyphosate induces locomotor, craniofacial, and bone disorders in zebrafish (Danio rerio) embryos

2021 ◽  
pp. 103700
Author(s):  
Rubén D. Díaz-Martín ◽  
Ana Carvajal-Peraza ◽  
Beatriz Yáñez-Rivera ◽  
Miguel Betancourt-Lozano
Keyword(s):  
Danio Rerio ◽  
Short Exposure ◽  
Bone Disorders ◽  
Danio Rerio Embryos

Effects of the brominated flame retardant, TBCO, on development of zebrafish (Danio rerio) embryos

Chemosphere ◽  
2021 ◽  
Vol 266 ◽  
pp. 129195
Author(s):  
Darren Van Essen ◽  
Chloe Devoy ◽  
Justin Miller ◽  
Paul D. Jones ◽  
Steve Wiseman
Keyword(s):  
Flame Retardant ◽  
Danio Rerio ◽  
Brominated Flame Retardant ◽  
Danio Rerio Embryos

Simvastatin effects on detoxification mechanisms in Danio rerio embryos

2016 ◽  
Vol 23 (11) ◽  
pp. 10615-10629 ◽  
Author(s):  
V. Cunha ◽  
M. M. Santos ◽  
P. Moradas-Ferreira ◽  
M. Ferreira
Keyword(s):  
Danio Rerio ◽  
Detoxification Mechanisms ◽  
Danio Rerio Embryos

scholarly journals Morpholino-Mediated Knockdown of ERα, ERβa, and ERβb mRNAs in Zebrafish (Danio rerio) Embryos Reveals Differential Regulation of Estrogen-Inducible Genes

Endocrinology ◽  
2013 ◽  
Vol 154 (11) ◽  
pp. 4158-4169 ◽  
Author(s):  
Lucinda B. Griffin ◽  
Kathleen E. January ◽  
Karen W. Ho ◽  
Kellie A. Cotter ◽  
Gloria V. Callard
Keyword(s):  
Danio Rerio ◽  
Specific Gene ◽  
Estrogen Action ◽  
Cytochrome P450 Aromatase ◽  
Retained Intron ◽  
Inducible Genes ◽  
Hepatic Genes ◽  
Danio Rerio Embryos

Genetically distinct estrogen receptor (ER) subtypes (ERα and ERβ) play a major role in mediating estrogen actions in vertebrates, but their unique and overlapping functions are not entirely clear. Although mammals have 1 gene of each subtype (ESR1 and ESR2), teleost fish have a single esr1 (ERα) and 2 esr2 (ERβa and ERβb) genes. To determine the in vivo role of different ER isoforms in regulating estrogen-inducible transcription targets, zebrafish (Danio rerio) embryos were microinjected with esr-specific morpholino (MO) oligonucleotides to disrupt splicing of the exon III/intron III junction in the DNA-binding domain. Each MO knocked down its respective normal transcript and increased production of variants with a retained intron III (esr1 MO) or a deleted or mis-spliced exon III (esr2a and esr2b MOs). Both esr1 and esr2b MOs blocked estradiol induction of vitellogenin and ERα mRNAs, predominant hepatic genes, but esr2b was the only MO that blocked induction of cytochrome P450 aromatase B mRNA, a predominant brain gene. Knockdown of ERβa with the esr2a MO had no effect on estrogen induction of the 3 mRNAs but, when coinjected with esr1 MO, attenuated the effect of ERα knockdown. Results indicate that ERα and ERβb, acting separately or cooperatively on specific gene targets, are positive transcriptional regulators of estrogen action, but the role of ERβa, if any, is unclear. We conclude that MO technology in zebrafish embryos is an advantageous approach for investigating the interplay of ER subtypes in a true physiological context.

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