Direct high-performance liquid chromatography method with refractometric detection designed for stability studies of treosulfan and its biologically active epoxy-transformers

2013 ◽  
Vol 72 ◽  
pp. 145-149 ◽  
Author(s):  
Franciszek K. Główka ◽  
Michał Romański ◽  
Artur Teżyk ◽  
Czesław Żaba
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Biologically Active ◽  
Stability Studies ◽  
Chromatography Method ◽  
Liquid Chromatography Method ◽  
Refractometric Detection

Fast determination of omeprazole in extemporaneous suspensions used in paediatrics and stability studies

2019 ◽  
Vol 11 (4) ◽  
pp. 517-523 ◽  
Author(s):  
Kateřina Kučerová ◽  
Veronika Reiská ◽  
František Švec ◽  
Lenka Kujovská Krčmová ◽  
Ludmila Matysová
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Internal Standard ◽  
Uv Detection ◽  
Stability Studies ◽  
Chromatography Method ◽  
Fast Determination ◽  
Liquid Chromatography Method

A simple and fast ultra-high-performance liquid chromatography method with UV detection for the separation and quantification of omeprazole and the impurities of omeprazole and methylparaben (the internal standard) in six extemporaneous suspensions has been developed and fully validated.

scholarly journals HPLC Quantification of Cytotoxic Compounds fromAspergillus niger

2017 ◽  
Vol 2017 ◽  
pp. 1-7
Author(s):  
Paula Karina S. Uchoa ◽  
Leandro Bezerra de Lima ◽  
Antonia T. A. Pimenta ◽  
Maria da Conceição F. de Oliveira ◽  
Jair Mafezoli ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Standard Deviation ◽  
High Performance ◽  
Chromatography Method ◽  
Relative Standard ◽  
Validation Parameters ◽  
Cytotoxic Compounds ◽  
Liquid Chromatography Method ◽  
Marine Strain

A high-performance liquid chromatography method was developed and validated for the quantification of the cytotoxic compounds produced by a marine strain ofAspergillus niger. The fungus was grown in malt peptone dextrose (MPD), potato dextrose yeast (PDY), and mannitol peptone yeast (MnPY) media during 7, 14, 21, and 28 days, and the natural products were identified by standard compounds. The validation parameters obtained were selectivity, linearity (coefficient of correlation > 0.99), precision (relative standard deviation below 5%), and accuracy (recovery > 96).

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