Simultaneous determination of betulin and betulinic acid in white birch bark using RP-HPLC

2007 ◽  
Vol 43 (3) ◽  
pp. 959-962 ◽  
Author(s):  
Guoling Zhao ◽  
Weidong Yan ◽  
Dan Cao
Keyword(s):  
Simultaneous Determination ◽  
Betulinic Acid ◽  
Birch Bark ◽  
White Birch ◽  
Rp Hplc

RP-HPLC method development for simultaneous determination of the drugs Ramipril and Amlodipine

2012 ◽  
Vol 2 (2) ◽  
pp. 364-367 ◽  
Author(s):  
Saida Naik Dheeravath ◽  
◽  
Kasani Ramadevi ◽  
Zilla Saraswathi ◽  
Dheeravath Maniklal ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Method Development ◽  
Hplc Method ◽  
Rp Hplc ◽  
Hplc Method Development

Simultaneous Determination of Chloroquine and Pyrimethamine with Cetirizine in an Active Form and Human Serum by RP-HPLC

2021 ◽  
Author(s):  
Hina Shamshad ◽  
Ali Sayqal ◽  
Jahan Zeb ◽  
Agha Zeeshan Mirza
Keyword(s):  
Human Serum ◽  
Simultaneous Determination ◽  
Active Form ◽  
Internal Standard ◽  
Hplc Method ◽  
Serum Samples ◽  
Rp Hplc ◽  
Cetirizine Hydrochloride ◽  
Bulk Drug

Abstract A simple, accurate and precise RP-HPLC method was developed for the simultaneous determination of chloroquine, pyrimethamine and cetirizine hydrochloride concentrations in bulk drug and human serum. The assay was performed using a mobile phase of methanol: water (70:30) at pH of 2.8 ± 0.05 on the Purospher C-18 column with UV detection at 230 nm and rosuvastatin used as an internal standard. The retention times observed for chloroquine, pyrimethamine and cetirizine hydrochloride were 3.5, 2.5 and 5.5 minutes, respectively. The method was found to be specific for the assayed drugs showing a linear response in the concentration range of 1–100 μg mL−1 with coefficients of determination values of (r = 0.999). The method was developed and validated according to ICH guidelines. The method was used to monitor the serum samples and was found to be sensitive for therapeutic purposes, showing the potential to be a useful tool for routine analysis in laboratories.

Validated stability-indicating RP-HPLC UV method for simultaneous determination of metformin and repaglinide

2012 ◽  
Vol 24 (3) ◽  
pp. 419-432 ◽  
Author(s):  
S. S. Joshi ◽  
R. R. Nahire ◽  
N. R. Shastri ◽  
K. V. Surendranath ◽  
J. Satish
Keyword(s):  
Simultaneous Determination ◽  
Stability Indicating ◽  
Rp Hplc

scholarly journals SIMULTANEOUS DETERMINATION OF LEVODROPROPIZINE, METHYLPARABEN, AND PROPYLPARABEN IN ORAL CO-FORMULATED SYRUP BY RP-HPLC METHOD

2015 ◽  
Vol 60 (4) ◽  
pp. 2729-2733 ◽  
Author(s):  
SOHEIR ABD EL-FATAH WESHAHY ◽  
MAISSA SALEM YAAQOB ◽  
MARIANNE NEBSEN MORCOS ◽  
DINA WAHBA HASSAN ◽  
NADIA FAYEK YOUSSEF
Keyword(s):  
Simultaneous Determination ◽  
Hplc Method ◽  
Rp Hplc
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