Association Between Polymorphisms in Serotonin and Dopamine-Related Genes and Endogenous Pain Modulation

2011 ◽  
Vol 12 (8) ◽  
pp. 875-883 ◽  
Author(s):  
Roi Treister ◽  
Dorit Pud ◽  
Richard P. Ebstein ◽  
Efrat Laiba ◽  
Yael Raz ◽  
...  
Keyword(s):  
Pain Modulation ◽  
Endogenous Pain Modulation

scholarly journals Training volume is associated with pain sensitivity, but not with endogenous pain modulation, in competitive swimmers

2019 ◽  
Vol 37 ◽  
pp. 150-156 ◽  
Author(s):  
Kevin Kuppens ◽  
Stef Feijen ◽  
Nathalie Roussel ◽  
Jo Nijs ◽  
Patrick Cras ◽  
...  
Keyword(s):  
Pain Sensitivity ◽  
Pain Modulation ◽  
Training Volume ◽  
Endogenous Pain Modulation ◽  
Competitive Swimmers

Experimental evidence for weaker endogenous inhibition of trigeminal pain than extra-trigeminal pain in healthy individuals

Cephalalgia ◽  
2017 ◽  
Vol 38 (7) ◽  
pp. 1307-1315 ◽  
Author(s):  
Dan Levy ◽  
Lorin Abdian ◽  
Michal Dekel-Steinkeller ◽  
Ruth Defrin
Keyword(s):  
Pain Control ◽  
Pain Modulation ◽  
Primary Headaches ◽  
Healthy Individuals ◽  
Trigeminal Pain ◽  
Pain Syndromes ◽  
Body Regions ◽  
Endogenous Pain Modulation ◽  
High Prevalence ◽  
Pain Inhibition

Background and objectives The prevalence of pain syndromes that affect the territories innervated by the trigeminal nerve, such as headaches, is one of the highest and ranks second only to low back pain. A potential mechanism underlying this high prevalence may be a relatively weak endogenous pain modulation of trigeminal pain. Here, we sought to systematically compare endogenous pain modulation capabilities in the trigeminal region to those of extra-trigeminal regions in healthy subjects. Methods Healthy, pain free subjects (n = 17) underwent a battery of quantitative sensory testing to assess endogenous pain inhibition and pain enhancement efficiencies within and outside the trigeminal innervated region. Measurements included conditioned pain modulation (CPM), temporal summation of pain (TSP) and spatial summation of pain (SSP). Results Testing configurations that included trigeminal-innervated body regions displayed significantly weaker CPM when compared to extra-trigeminal innervated areas. SSP magnitude was smaller in the ophthalmic trigeminal innervation when compared to other body regions. TSP magnitude was not different between the different body regions tested. Conclusions Our findings point to regional differences in endogenous pain inhibition and suggest that in otherwise healthy individuals, the trigeminal innervation is subjected to a weaker inhibitory pain control than other body regions. Such weaker endogenous pain control could play, at least in part, a role in mediating the high prevalence of trigeminal-related pain syndromes, including primary headaches and TMD pain.

Effects of Spinal Cord and Peripheral Nerve Stimulation Reflected in Sensory Profiles and Endogenous Pain Modulation

2019 ◽  
Vol 35 (2) ◽  
pp. 111-120 ◽  
Author(s):  
Christine H. Meyer-Frießem ◽  
Theresa Wiegand ◽  
Lynn Eitner ◽  
Christoph Maier ◽  
Tina Mainka ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Peripheral Nerve ◽  
Nerve Stimulation ◽  
Pain Modulation ◽  
Peripheral Nerve Stimulation ◽  
Endogenous Pain Modulation ◽  
Sensory Profiles

Endogenous Pain Modulation Induced by Extrinsic and Intrinsic Psychological Threat in Healthy Individuals

2018 ◽  
Vol 19 (3) ◽  
pp. 330-339 ◽  
Author(s):  
William Gibson ◽  
Penny Moss ◽  
Tak Ho Cheng ◽  
Alexandre Garnier ◽  
Anthony Wright ◽  
...  
Keyword(s):  
Pain Modulation ◽  
Healthy Individuals ◽  
Endogenous Pain Modulation ◽  
Psychological Threat
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