Examining associations between thought-action fusion and state mental contamination following an in vivo thought induction task

Author(s):  
Thomas A. Fergus ◽  
Wade C. Rowatt
2018 ◽  
Author(s):  
Rosemond T. Lorona ◽  
Wade C. Rowatt ◽  
Thomas A. Fergus

2011 ◽  
Vol 25 (2) ◽  
pp. 155-164 ◽  
Author(s):  
Noah C. Berman ◽  
Jonathan S. Abramowitz ◽  
Michael G. Wheaton ◽  
Caleb Pardue ◽  
Laura Fabricant

Thought–action fusion (TAF) refers to maladaptive beliefs about the relationship between mental events and behaviors, and is associated with obsessional problems. Currently, the self-report Thought–Action Fusion Scale (TAFS) is the most widely used measure of TAF, but a single assessment modality limits research that can be conducted on this phenomenon. This study evaluated the validity of an in vivo paradigm that assesses both Moral TAF (the belief that thoughts are the moral equivalent of actions) and Likelihood TAF (the belief that thinking about a negative event increases the probability of the event itself). In this paradigm, participants were asked to contemplate two negative events involving a beloved relative: (a) I hope (relative) is in a car accident today and (b) I hope I have sex with (relative). Participants then provided in vivo ratings of anxiety, estimates of likelihood, and moral wrongness related to the negative thoughts. Results provided evidence for the convergent validity of the in vivo ratings for both sentences. These findings are discussed in terms of clinical care, the assessment of TAF, and the implications for future research on this theoretically important construct.


2010 ◽  
Vol 48 (7) ◽  
pp. 670-674 ◽  
Author(s):  
Noah C. Berman ◽  
Jonathan S. Abramowitz ◽  
Caleb M. Pardue ◽  
Michael G. Wheaton

Author(s):  
S. Phyllis Steamer ◽  
Rosemarie L. Devine

The importance of radiation damage to the skin and its vasculature was recognized by the early radiologists. In more recent studies, vascular effects were shown to involve the endothelium as well as the surrounding connective tissue. Microvascular changes in the mouse pinna were studied in vivo and recorded photographically over a period of 12-18 months. Radiation treatment at 110 days of age was total body exposure to either 240 rad fission neutrons or 855 rad 60Co gamma rays. After in vivo observations in control and irradiated mice, animals were sacrificed for examination of changes in vascular fine structure. Vessels were selected from regions of specific interest that had been identified on photomicrographs. Prominent ultrastructural changes can be attributed to aging as well as to radiation treatment. Of principal concern were determinations of ultrastructural changes associated with venous dilatations, segmental arterial stenosis and tortuosities of both veins and arteries, effects that had been identified on the basis of light microscopic observations. Tortuosities and irregularly dilated vein segments were related to both aging and radiation changes but arterial stenosis was observed only in irradiated animals.


Author(s):  
E. J. Kollar

The differentiation and maintenance of many specialized epithelial structures are dependent on the underlying connective tissue stroma and on an intact basal lamina. These requirements are especially stringent in the development and maintenance of the skin and oral mucosa. The keratinization patterns of thin or thick cornified layers as well as the appearance of specialized functional derivatives such as hair and teeth can be correlated with the specific source of stroma which supports these differentiated expressions.


Author(s):  
M.J. Murphy ◽  
R.R. Price ◽  
J.C. Sloman

The in vitro human tumor cloning assay originally described by Salmon and Hamburger has been applied recently to the investigation of differential anti-tumor drug sensitivities over a broad range of human neoplasms. A major problem in the acceptance of this technique has been the question of the relationship between the cultured cells and the original patient tumor, i.e., whether the colonies that develop derive from the neoplasm or from some other cell type within the initial cell population. A study of the ultrastructural morphology of the cultured cells vs. patient tumor has therefore been undertaken to resolve this question. Direct correlation was assured by division of a common tumor mass at surgical resection, one biopsy being fixed for TEM studies, the second being rapidly transported to the laboratory for culture.


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