scholarly journals Chondrogenic differentiation potential of CD56+ satellite cell and PDGFRα+ mesenchymal stem cell derived from human skeletal muscle

2012 ◽  
Vol 20 ◽  
pp. S270-S271
Author(s):  
T. Oishi ◽  
A. Uezumi ◽  
A. Kanaji ◽  
K. Tsuchida ◽  
H. Yamada
Keyword(s):  
Skeletal Muscle ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Satellite Cell ◽  
Chondrogenic Differentiation ◽  
Human Skeletal Muscle ◽  
Differentiation Potential

Mesenchymal-stem-cell-derived exosomes accelerate skeletal muscle regeneration

FEBS Letters ◽  
2015 ◽  
Vol 589 (11) ◽  
pp. 1257-1265 ◽  
Author(s):  
Yoshihiro Nakamura ◽  
Shigeru Miyaki ◽  
Hiroyuki Ishitobi ◽  
Sho Matsuyama ◽  
Tomoyuki Nakasa ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Muscle Regeneration ◽  
Skeletal Muscle Regeneration

scholarly journals Correlation Between Compositional and Mechanical Properties of Human Mesenchymal Stem Cell-Collagen Microspheres During Chondrogenic Differentiation

2011 ◽  
Vol 17 (5-6) ◽  
pp. 777-788 ◽  
Author(s):  
Chun-hei Li ◽  
Tsz-Kit Chik ◽  
Alfonso H.W. Ngan ◽  
Stanley C.H. Chan ◽  
Daisy K.Y. Shum ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Chondrogenic Differentiation ◽  
Human Mesenchymal Stem Cell

scholarly journals Isolation and Characterization of a Human Fetal Mesenchymal Stem Cell Population: Exploring the Potential for Cell Banking in Wound Healing Therapies

2019 ◽  
Vol 28 (11) ◽  
pp. 1404-1419
Author(s):  
Roger Esteban-Vives ◽  
Jenny Ziembicki ◽  
Myung Sun Choi ◽  
R. L. Thompson ◽  
Eva Schmelzer ◽  
...  
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Dermal Fibroblasts ◽  
Stem Cell Population ◽  
Differentiation Potential ◽  
Isolation And Characterization ◽  
Cell Banking ◽  
Lineage Stability

Various cell-based therapies are in development to address chronic and acute skin wound healing, for example for burns and trauma patients. An off-the-shelf source of allogeneic dermal cells could be beneficial for innovative therapies accelerating the healing in extensive wounds where the availability of a patient’s own cells is limited. Human fetal-derived dermal fibroblasts (hFDFs) show high in vitro division rates, exhibit low immunological rejection properties, and present scarless wound healing in the fetus, and previous studies on human fetal tissue-derived cell therapies have shown promising results on tissue repair. However, little is known about cell lineage stability and cell differentiation during the cell expansion process, required for any potential therapeutic use. We describe an isolation method, characterize a population, and investigate its potential for cell banking and thus suitability as a potential product for cell grafting therapies. Our results show hFDFs and a bone marrow-derived mesenchymal stem cell (BM-MSC) line shared identification markers and in vitro multilineage differentiation potential into osteogenic, chondrogenic, and adipogenic lineages. The hFDF population exhibited similar cell characteristics as BM-MSCs while producing lower pro-inflammatory cytokine IL-6 levels and higher levels of the wound healing factor hepatocyte growth factor. We demonstrate in vitro differentiation of hFDFs, which may be a problem in maintaining long-term lineage stability, potentially limiting their use for cell banking and therapy development.

scholarly journals The Skeletal Muscle Satellite Cell: The Stem Cell That Came in From the Cold

2006 ◽  
Vol 54 (11) ◽  
pp. 1177-1191 ◽  
Author(s):  
Peter S. Zammit ◽  
Terence A. Partridge ◽  
Zipora Yablonka-Reuveni
Keyword(s):  
Skeletal Muscle ◽  
Stem Cell ◽  
Satellite Cell ◽  
Muscle Satellite Cell ◽  
Skeletal Muscle Satellite Cell
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